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85 Top San Francisco Cryptocurrency Companies and Startups of 2021

This article showcases our top picks for the best San Francisco based Cryptocurrency companies. These startups and companies are taking a variety of approaches to innovating the Cryptocurrency industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top San Francisco Cryptocurrency Startups

Data sourced from Crunchbase and SemRush.

Ripple

Ripple

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Ripple provides one frictionless experience to send money globally using the power of blockchain.

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Bitwise

Crunchbase Website Twitter Facebook Linkedin

Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

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Coinbase

Crunchbase Website Twitter Facebook Linkedin

Coinbase is an online platform that allows merchants, consumers, and traders to transact with digital currency.

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Uphold

Crunchbase Website Twitter Facebook Linkedin

Uphold is a digital wallet and trading platform that enables cryptocurrencies and other assets affordable and accessible for everyone.

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Solana

Crunchbase Website Twitter Facebook Linkedin

Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

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FTX Exchange

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FTX Exchange is a cryptocurrency derivatives exchange company built by traders, for traders.

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TRM Labs

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TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

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dYdX

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dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

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Helium

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Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

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Stellar Development Foundation

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A non-profit organization that supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

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Bitski

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Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

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Wyre

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Wyre develops a wide variety of payment APIs that offer a fast and cost-effective way of transferring money.

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Chia Network

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Chia Network is building a blockchain platform based on Proofs of Space and Time.

CoinList

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CoinList provides a platform for digital asset companies to run their token sales.

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Set Labs

Crunchbase Website Twitter Facebook Linkedin

Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

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Compound

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Compound is an open-source interest rate protocol that unlocks new financial applications.

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TrustToken

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TrustToken is a platform to create asset-backed tokens that can be used for buying and selling around the world.

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Hashflow

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Hashflow is a hybrid approach to decentralized finance (DeFi) trading.

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Eco

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Eco provides a digital global cryptocurrency platform that can be used as a payment tool for daily-use transactions.

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Harbor

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Harbor is helping to power the next big wave in capital markets – tokenized securities – by automating regulatory compliance.

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O(1) Labs

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O(1) Labs is a software development company working on Mina Protocol, a tiny, portable blockchain.

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0x

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0x is an open protocol that enables peer-to-peer trading of assets.

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Aleo

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Aleo is building the world’s leading developer platform for enabling absolute privacy on blockchains.

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MobileCoin

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MobileCoin is a cryptocurrency platform that develops P2P payment tokens and digital payment systems for mobile.

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River Financial

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River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

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NuCypher

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NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

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SKALE Labs

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SKALE Labs is a blockchain scalability platform that provides high speed consensus and empowers dApps to run smart contracts.

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CoinTracker

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CoinTracker is a portfolio and tax manager for cryptocurrency.

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Securitize

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Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

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Kava Labs

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Kava Labs is a developer of Kava, is the most trusted DeFi platform by financial institutions

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Fei Protocol

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Fei Protocol is a direct incentive stable coin which is undercollateralized and fully decentralized.

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Digital Finance Group

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Diversified investment group that manages $1B in digital & blockchain assets across multiple funds, an incubator and global projects

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Omniex

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Omniex develops software infrastructure that integrates front, middle, and back-office services to simplify access and remove fragmentation.

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Opyn

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Opyn allows users to earn a premium or take views on assets by trading options on ETH and ERC20s.

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Reflexer Labs

Crunchbase Website Twitter Facebook Linkedin

Reflexer Labs is a new decentralized finance project aimed at softening volatility.

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Coinbase Ventures

Crunchbase Website Twitter Facebook Linkedin

Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

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CryptiSwap

Crunchbase Website Twitter Facebook Linkedin

CryptiSwap© is a Non-Custodial CryptoCurrency exchange/swap service | no registration | no holds | no third party

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Iron Fish

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Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

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Rare Bits

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Rare Bits is a zero-fee peer-to-peer marketplace to buy, sell, and discover crypto goods.

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Connext

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Connext is a crosschain liquidity network that enables fast, fully-noncustodial transfers between EVM-compatible chains and L2 systems.

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Snowball Money

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Snowball Money operates as a crypto investment automation platform that provides access to professionally curated portfolios.

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Saddle Finance

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Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

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BarnBridge

Crunchbase Website Twitter Facebook Linkedin

Tokenized risk protocol

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Mudrex

Crunchbase Website Twitter Facebook Linkedin

Smart crypto investment on autopilot

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Apto Payments

Crunchbase Website Twitter Facebook Linkedin

Apto Payments is a card issuance platform that helps companies issue new kinds of cards in new ways.

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Zerion

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Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

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Agoric

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Agoric provides a framework for programming smart contracts securely and with ease, beyond anything available today.

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Sperax

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Sperax builds the most secure and scalable infrastructure for decentralized financial services.

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Polkaswitch

Crunchbase Website Twitter Facebook Linkedin

A decentralized multi-chain liquidity protocol on Polkadot, Ethereum, and top layer 1 & 2 blockchains.

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Coinbase CBT

Crunchbase Website Twitter Facebook Linkedin

Coinbase CBT is a IEO fund raising project of Coinbase that aims to connect with millions of crypto investors around the world.

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Async Art

Crunchbase Website Twitter Facebook Linkedin

Collect and Experience Rare Programmable Art.

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AnchorUSD

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AnchorUSD offers stable currency anchored 1-for-1 to the US dollar (USDX).

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Commonwealth Labs

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Commonwealth Labs is a governance startup offering a new twist on token airdrops.

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Slingshot Finance

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Next-gen decentralized trading platform

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CASPIAN

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CASPIAN is a full stack crypto asset management solution.

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Multis

Crunchbase Website Twitter Facebook Linkedin

Multis provides financial services for companies holding euros, dollars, and cryptocurrencies.

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Anchorage

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Anchorage is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

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Provenance Blockchain

Crunchbase Website Twitter Facebook Linkedin

Provenance Blockchain combines the distributed, trustless, and immutable characteristics of blockchain.

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Risk Harbor

Crunchbase Website Twitter Facebook Linkedin

The only objective risk management marketplace for decentralized finance (DeFi).

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Linen App

Crunchbase Website Twitter Facebook Linkedin

New experience that allows our members to earn high yield on their cash.

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Round Finance Inc.

Crunchbase Website Twitter Facebook Linkedin

Building an aggregator of digital assets and experiences

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BLADE

Crunchbase Website Twitter Facebook Linkedin

BLADE is a cryptocurrency derivatives exchange

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Idex.io

Crunchbase Website Twitter Facebook Linkedin

Idex.io is a decentralized cryptocurrency exchange.

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Purse

Crunchbase Website Twitter Facebook Linkedin

Purse provides real incentive to use Bitcoin to the largest selection at the lowest price points.

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SureRemit

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SureRemit is an ecosystem for global non-cash remittances.

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Bitnet Technologies

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Bitnet Technologies is a digital commerce platform that helps enterprise scale merchants to accept bitcoin payments.

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gumi Cryptos Capital (gCC)

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gumi Cryptos Capital is a blockchain and cryptographic asset venture fund

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Yours

Crunchbase Website Twitter Facebook Linkedin

Yours is a blockchain-based social network where users can earn bitcoin.

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DCEX

Crunchbase Website Twitter Facebook Linkedin

DCEX is a US based digital currency exchange with OTC desk, digital dollar DCEX$ and a Digital currency news site

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ZeFi

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ZeFi develops a neobanking platform that provides a permission less financial ecosystem without a central authority.

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TokenInsight

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TokenInsight is dedicated towards providing accurate data and ratings for cryptocurrency companies through transparency.

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Layer1

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Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

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Picks & Shovels

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The Picks & Shovels Co. crafting tools for investors and traders of digital currencies and crypto assets.

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Beanstalk Network

Crunchbase Website Twitter Facebook Linkedin

Beanstalk Network is a research and development company for privacy preserving financial transactions.

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MetaMask

Crunchbase Website Twitter Facebook Linkedin

MetaMask is a crypto wallet and gateway to blockchain apps.

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Apifiny

Crunchbase Website Twitter Facebook Linkedin

A global digital asset trading network unifying fragmented markets, providing superior liquidity and trade execution for professionals.

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StudentCoin

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StudentCoin is a universal cryptocurrency for students where the users owns 100% of the company.

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Hexel

Crunchbase Website Twitter Facebook Linkedin

Hexel is a startup that wants to make it easy for anyone to use Ethereum-based tokens to engage their hyperlocal community.

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Satochi

Crunchbase Website Twitter Facebook Linkedin

Fintech, Investing, Cryptocurrency, Consumer

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LoopX

Crunchbase Website Twitter Facebook Linkedin

LoopX is helps to find the Best Worldwide Online Casino and provides information.

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Bitbutter

Crunchbase Website Twitter Facebook Linkedin

Crypto-asset account aggregation API for fintechs and financial institutions.

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Volt Capital

Crunchbase Website Twitter Facebook Linkedin

Volt Capital is a research and community driven crypto fund.

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ChangeTip

Crunchbase Website Twitter Facebook Linkedin

ChangeTip facilitates global micropayments across every social media or digital platform.

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Dapps

Crunchbase Website Twitter Facebook Linkedin

Enterprise Blockchain Computing (EBC)

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Portal

Crunchbase Website Twitter Facebook Linkedin

Portal is a financial services company that trades crypto without putting coins at risk.

Written by Mark Smith

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