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85 Top San Francisco Cryptocurrency Companies and Startups of 2021 - Best Startup US

85 Top San Francisco Cryptocurrency Companies and Startups of 2021

June 18, 2021

This article showcases our top picks for the best San Francisco based Cryptocurrency companies. These startups and companies are taking a variety of approaches to innovating the Cryptocurrency industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top San Francisco Cryptocurrency Startups

Data sourced from Crunchbase and SemRush.

Ripple

Ripple

Crunchbase Website Twitter Facebook Linkedin

Ripple provides one frictionless experience to send money globally using the power of blockchain.

Bitwise

Bitwise

Crunchbase Website Twitter Facebook Linkedin

Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Bitwise

Coinbase

Crunchbase Website Twitter Facebook Linkedin

Coinbase is an online platform that allows merchants, consumers, and traders to transact with digital currency.

Bitwise

Uphold

Crunchbase Website Twitter Facebook Linkedin

Uphold is a digital wallet and trading platform that enables cryptocurrencies and other assets affordable and accessible for everyone.

Bitwise

Solana

Crunchbase Website Twitter Facebook Linkedin

Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

Bitwise

FTX Exchange

Crunchbase Website Twitter Facebook Linkedin

FTX Exchange is a cryptocurrency derivatives exchange company built by traders, for traders.

Bitwise

TRM Labs

Crunchbase Website Twitter Facebook Linkedin

TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

Bitwise

dYdX

Crunchbase Website Twitter Facebook Linkedin

dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

Bitwise

Helium

Crunchbase Website Twitter Facebook Linkedin

Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

Bitwise

Stellar Development Foundation

Crunchbase Website Twitter Facebook Linkedin

A non-profit organization that supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

Bitwise

Bitski

Crunchbase Website Twitter Facebook Linkedin

Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

Bitwise

Wyre

Crunchbase Website Twitter Facebook Linkedin

Wyre develops a wide variety of payment APIs that offer a fast and cost-effective way of transferring money.

Bitwise

Chia Network

Crunchbase Website Twitter Facebook Linkedin

Chia Network is building a blockchain platform based on Proofs of Space and Time.

CoinList

Crunchbase Website Twitter Facebook Linkedin

CoinList provides a platform for digital asset companies to run their token sales.

Bitwise

Set Labs

Crunchbase Website Twitter Facebook Linkedin

Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

Bitwise

Compound

Crunchbase Website Twitter Facebook Linkedin

Compound is an open-source interest rate protocol that unlocks new financial applications.

Bitwise

TrustToken

Crunchbase Website Twitter Facebook Linkedin

TrustToken is a platform to create asset-backed tokens that can be used for buying and selling around the world.

Bitwise

Hashflow

Crunchbase Website Twitter Facebook Linkedin

Hashflow is a hybrid approach to decentralized finance (DeFi) trading.

Bitwise

Eco

Crunchbase Website Twitter Facebook Linkedin

Eco provides a digital global cryptocurrency platform that can be used as a payment tool for daily-use transactions.

Bitwise

Harbor

Crunchbase Website Twitter Facebook Linkedin

Harbor is helping to power the next big wave in capital markets – tokenized securities – by automating regulatory compliance.

Bitwise

O(1) Labs

Crunchbase Website Twitter Facebook Linkedin

O(1) Labs is a software development company working on Mina Protocol, a tiny, portable blockchain.

Bitwise

0x

Crunchbase Website Twitter Facebook Linkedin

0x is an open protocol that enables peer-to-peer trading of assets.

Bitwise

Aleo

Crunchbase Website Twitter Facebook Linkedin

Aleo is building the world’s leading developer platform for enabling absolute privacy on blockchains.

Bitwise

MobileCoin

Crunchbase Website Twitter Facebook Linkedin

MobileCoin is a cryptocurrency platform that develops P2P payment tokens and digital payment systems for mobile.

Bitwise

River Financial

Crunchbase Website Twitter Facebook Linkedin

River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

Bitwise

NuCypher

Crunchbase Website Twitter Facebook Linkedin

NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

Bitwise

SKALE Labs

Crunchbase Website Twitter Facebook Linkedin

SKALE Labs is a blockchain scalability platform that provides high speed consensus and empowers dApps to run smart contracts.

Bitwise

CoinTracker

Crunchbase Website Twitter Facebook Linkedin

CoinTracker is a portfolio and tax manager for cryptocurrency.

Bitwise

Securitize

Crunchbase Website Twitter Facebook Linkedin

Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

Bitwise

Kava Labs

Crunchbase Website Twitter Facebook Linkedin

Kava Labs is a developer of Kava, is the most trusted DeFi platform by financial institutions

Bitwise

Fei Protocol

Crunchbase Website Twitter Facebook Linkedin

Fei Protocol is a direct incentive stable coin which is undercollateralized and fully decentralized.

Bitwise

Digital Finance Group

Crunchbase Website Twitter Facebook Linkedin

Diversified investment group that manages $1B in digital & blockchain assets across multiple funds, an incubator and global projects

Bitwise

Omniex

Crunchbase Website Twitter Facebook Linkedin

Omniex develops software infrastructure that integrates front, middle, and back-office services to simplify access and remove fragmentation.

Bitwise

Opyn

Crunchbase Website Twitter Facebook Linkedin

Opyn allows users to earn a premium or take views on assets by trading options on ETH and ERC20s.

Bitwise

Reflexer Labs

Crunchbase Website Twitter Facebook Linkedin

Reflexer Labs is a new decentralized finance project aimed at softening volatility.

Bitwise

Coinbase Ventures

Crunchbase Website Twitter Facebook Linkedin

Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

Bitwise

CryptiSwap

Crunchbase Website Twitter Facebook Linkedin

CryptiSwap© is a Non-Custodial CryptoCurrency exchange/swap service | no registration | no holds | no third party

Bitwise

Iron Fish

Crunchbase Website Twitter Facebook Linkedin

Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

Bitwise

Rare Bits

Crunchbase Website Twitter Facebook Linkedin

Rare Bits is a zero-fee peer-to-peer marketplace to buy, sell, and discover crypto goods.

Bitwise

Connext

Crunchbase Website Twitter Facebook Linkedin

Connext is a crosschain liquidity network that enables fast, fully-noncustodial transfers between EVM-compatible chains and L2 systems.

Bitwise

Snowball Money

Crunchbase Website Twitter Facebook Linkedin

Snowball Money operates as a crypto investment automation platform that provides access to professionally curated portfolios.

Bitwise

Saddle Finance

Crunchbase Website Twitter Facebook Linkedin

Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

Bitwise

BarnBridge

Crunchbase Website Twitter Facebook Linkedin

Tokenized risk protocol

Bitwise

Mudrex

Crunchbase Website Twitter Facebook Linkedin

Smart crypto investment on autopilot

Bitwise

Apto Payments

Crunchbase Website Twitter Facebook Linkedin

Apto Payments is a card issuance platform that helps companies issue new kinds of cards in new ways.

Bitwise

Zerion

Crunchbase Website Twitter Facebook Linkedin

Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

Bitwise

Agoric

Crunchbase Website Twitter Facebook Linkedin

Agoric provides a framework for programming smart contracts securely and with ease, beyond anything available today.

Bitwise

Sperax

Crunchbase Website Twitter Facebook Linkedin

Sperax builds the most secure and scalable infrastructure for decentralized financial services.

Bitwise

Polkaswitch

Crunchbase Website Twitter Facebook Linkedin

A decentralized multi-chain liquidity protocol on Polkadot, Ethereum, and top layer 1 & 2 blockchains.

Bitwise

Coinbase CBT

Crunchbase Website Twitter Facebook Linkedin

Coinbase CBT is a IEO fund raising project of Coinbase that aims to connect with millions of crypto investors around the world.

Bitwise

Async Art

Crunchbase Website Twitter Facebook Linkedin

Collect and Experience Rare Programmable Art.

Bitwise

AnchorUSD

Crunchbase Website Twitter Facebook Linkedin

AnchorUSD offers stable currency anchored 1-for-1 to the US dollar (USDX).

Bitwise

Commonwealth Labs

Crunchbase Website Twitter Facebook Linkedin

Commonwealth Labs is a governance startup offering a new twist on token airdrops.

Bitwise

Slingshot Finance

Crunchbase Website Twitter Facebook Linkedin

Next-gen decentralized trading platform

Bitwise

CASPIAN

Crunchbase Website Twitter Facebook Linkedin

CASPIAN is a full stack crypto asset management solution.

Bitwise

Multis

Crunchbase Website Twitter Facebook Linkedin

Multis provides financial services for companies holding euros, dollars, and cryptocurrencies.

Bitwise

Anchorage

Crunchbase Website Twitter Facebook Linkedin

Anchorage is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

Bitwise

Provenance Blockchain

Crunchbase Website Twitter Facebook Linkedin

Provenance Blockchain combines the distributed, trustless, and immutable characteristics of blockchain.

Bitwise

Risk Harbor

Crunchbase Website Twitter Facebook Linkedin

The only objective risk management marketplace for decentralized finance (DeFi).

Bitwise

Linen App

Crunchbase Website Twitter Facebook Linkedin

New experience that allows our members to earn high yield on their cash.

Bitwise

Round Finance Inc.

Crunchbase Website Twitter Facebook Linkedin

Building an aggregator of digital assets and experiences

Bitwise

BLADE

Crunchbase Website Twitter Facebook Linkedin

BLADE is a cryptocurrency derivatives exchange

Bitwise

Idex.io

Crunchbase Website Twitter Facebook Linkedin

Idex.io is a decentralized cryptocurrency exchange.

Bitwise

Purse

Crunchbase Website Twitter Facebook Linkedin

Purse provides real incentive to use Bitcoin to the largest selection at the lowest price points.

Bitwise

SureRemit

Crunchbase Website Twitter Facebook Linkedin

SureRemit is an ecosystem for global non-cash remittances.

Bitwise

Bitnet Technologies

Crunchbase Website Twitter Facebook Linkedin

Bitnet Technologies is a digital commerce platform that helps enterprise scale merchants to accept bitcoin payments.

Bitwise

gumi Cryptos Capital (gCC)

Crunchbase Website Twitter Facebook Linkedin

gumi Cryptos Capital is a blockchain and cryptographic asset venture fund

Bitwise

Yours

Crunchbase Website Twitter Facebook Linkedin

Yours is a blockchain-based social network where users can earn bitcoin.

Bitwise

DCEX

Crunchbase Website Twitter Facebook Linkedin

DCEX is a US based digital currency exchange with OTC desk, digital dollar DCEX$ and a Digital currency news site

Bitwise

ZeFi

Crunchbase Website Twitter Facebook Linkedin

ZeFi develops a neobanking platform that provides a permission less financial ecosystem without a central authority.

Bitwise

TokenInsight

Crunchbase Website Twitter Facebook Linkedin

TokenInsight is dedicated towards providing accurate data and ratings for cryptocurrency companies through transparency.

Bitwise

Layer1

Crunchbase Website Twitter Facebook Linkedin

Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

Bitwise

Picks & Shovels

Crunchbase Website Twitter Facebook Linkedin

The Picks & Shovels Co. crafting tools for investors and traders of digital currencies and crypto assets.

Bitwise

Beanstalk Network

Crunchbase Website Twitter Facebook Linkedin

Beanstalk Network is a research and development company for privacy preserving financial transactions.

Bitwise

MetaMask

Crunchbase Website Twitter Facebook Linkedin

MetaMask is a crypto wallet and gateway to blockchain apps.

Bitwise

Apifiny

Crunchbase Website Twitter Facebook Linkedin

A global digital asset trading network unifying fragmented markets, providing superior liquidity and trade execution for professionals.

Bitwise

StudentCoin

Crunchbase Website Twitter Facebook Linkedin

StudentCoin is a universal cryptocurrency for students where the users owns 100% of the company.

Bitwise

Hexel

Crunchbase Website Twitter Facebook Linkedin

Hexel is a startup that wants to make it easy for anyone to use Ethereum-based tokens to engage their hyperlocal community.

Bitwise

Satochi

Crunchbase Website Twitter Facebook Linkedin

Fintech, Investing, Cryptocurrency, Consumer

Bitwise

LoopX

Crunchbase Website Twitter Facebook Linkedin

LoopX is helps to find the Best Worldwide Online Casino and provides information.

Bitwise

Bitbutter

Crunchbase Website Twitter Facebook Linkedin

Crypto-asset account aggregation API for fintechs and financial institutions.

Bitwise

Volt Capital

Crunchbase Website Twitter Facebook Linkedin

Volt Capital is a research and community driven crypto fund.

Bitwise

ChangeTip

Crunchbase Website Twitter Facebook Linkedin

ChangeTip facilitates global micropayments across every social media or digital platform.

Bitwise

Dapps

Crunchbase Website Twitter Facebook Linkedin

Enterprise Blockchain Computing (EBC)

Bitwise

Portal

Crunchbase Website Twitter Facebook Linkedin

Portal is a financial services company that trades crypto without putting coins at risk.

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