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101 Top San Francisco Blockchain Companies and Startups of 2021 - Best Startup US

101 Top San Francisco Blockchain Companies and Startups of 2021

June 18, 2021
Top Companies (Navigation) show

This article showcases our top picks for the best San Francisco based Blockchain companies. These startups and companies are taking a variety of approaches to innovating the Blockchain industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top San Francisco Blockchain Startups

Data sourced from Crunchbase and SemRush.

Ripple

Ripple

Crunchbase Website Twitter Facebook Linkedin

Ripple provides one frictionless experience to send money globally using the power of blockchain.

Kraken

Kraken

Crunchbase Website Twitter Facebook Linkedin

Kraken is a cryptocurrency exchange that provides spot and futures trading between Bitcoin, Ethereum and 40+ other digital assets.

Kraken

Figure

Crunchbase Website Twitter Facebook Linkedin

Figure is a financial services company leveraging blockchain technology.

QuarkChain

Crunchbase Website Twitter Facebook Linkedin

QuarkChain is a flexible, scalable, and user-oriented blockchain infrastructure by applying blockchain sharding technology. QuarkChain has proved its advanced technology and brought impact in the industry over years.

Kraken

Bitwise

Crunchbase Website Twitter Facebook Linkedin

Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Kraken

Coinbase

Crunchbase Website Twitter Facebook Linkedin

Coinbase is an online platform that allows merchants, consumers, and traders to transact with digital currency.

Kraken

Uphold

Crunchbase Website Twitter Facebook Linkedin

Uphold is a digital wallet and trading platform that enables cryptocurrencies and other assets affordable and accessible for everyone.

Kraken

Solana

Crunchbase Website Twitter Facebook Linkedin

Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

Kraken

TRM Labs

Crunchbase Website Twitter Facebook Linkedin

TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

Kraken

dYdX

Crunchbase Website Twitter Facebook Linkedin

dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

Kraken

Helium

Crunchbase Website Twitter Facebook Linkedin

Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

Kraken

Stellar Development Foundation

Crunchbase Website Twitter Facebook Linkedin

A non-profit organization that supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

Kraken

Okcoin

Crunchbase Website Twitter Facebook Linkedin

One of the world’s largest cryptocurrency exchanges, Okcoin is building an inclusive future of finance for all.

Kraken

Forte

Crunchbase Website Twitter Facebook Linkedin

We’re building economic technology for games using blockchain.

Kraken

Bitski

Crunchbase Website Twitter Facebook Linkedin

Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

Kraken

Brave

Crunchbase Website Twitter Facebook Linkedin

Brave Software focuses on increasing browsing speed and safety for users, while growing ad revenue share for content creators.

Kraken

Veem

Crunchbase Website Twitter Facebook Linkedin

Veem is a payment service provider that helps simplify the way businesses send and receive funds.

Kraken

Chia Network

Crunchbase Website Twitter Facebook Linkedin

Chia Network is building a blockchain platform based on Proofs of Space and Time.

CoinList

Crunchbase Website Twitter Facebook Linkedin

CoinList provides a platform for digital asset companies to run their token sales.

Kraken

Set Labs

Crunchbase Website Twitter Facebook Linkedin

Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

Kraken

Compound

Crunchbase Website Twitter Facebook Linkedin

Compound is an open-source interest rate protocol that unlocks new financial applications.

Kraken

Celo

Crunchbase Website Twitter Facebook Linkedin

Celo is an open platform that makes financial tools accessible to anyone with a mobile phone.

Kraken

Ankr

Crunchbase Website Twitter Facebook Linkedin

Ankr is a Web3-native infrastructure platform.

Kraken

Rally

Crunchbase Website Twitter Facebook Linkedin

Rally provides a blockchain platform for the development of video streaming and gaming apps.

Kraken

TrustToken

Crunchbase Website Twitter Facebook Linkedin

TrustToken is a platform to create asset-backed tokens that can be used for buying and selling around the world.

Kraken

Oasis Labs

Crunchbase Website Twitter Facebook Linkedin

Oasis Labs is a privacy-first cloud computing platform on blockchain technology.

Kraken

Unstoppable Domains

Crunchbase Website Twitter Facebook Linkedin

Unstoppable Domains launches domains secured by blockchains and builds uncensorable websites.

Kraken

Proxy

Crunchbase Website Twitter Facebook Linkedin

Proxy provides a smartphone-enabled digital identity that allows the user to authenticate and interact with all devices.

Kraken

Harbor

Crunchbase Website Twitter Facebook Linkedin

Harbor is helping to power the next big wave in capital markets – tokenized securities – by automating regulatory compliance.

Kraken

O(1) Labs

Crunchbase Website Twitter Facebook Linkedin

O(1) Labs is a software development company working on Mina Protocol, a tiny, portable blockchain.

Kraken

0x

Crunchbase Website Twitter Facebook Linkedin

0x is an open protocol that enables peer-to-peer trading of assets.

Kraken

Aleo

Crunchbase Website Twitter Facebook Linkedin

Aleo is building the world’s leading developer platform for enabling absolute privacy on blockchains.

Kraken

Numerai

Crunchbase Website Twitter Facebook Linkedin

Numerai transforms and regularizes financial data into machine learning problems for global network of data scientists.

Kraken

Civic

Crunchbase Website Twitter Facebook Linkedin

Civic is a blockchain based ecosystem gives businesses and individuals the tools to control and protect identities.

Kraken

Origin Protocol

Crunchbase Website Twitter Facebook Linkedin

Origin Protocol is a blockchain platform for building decentralized marketplaces.

Kraken

River Financial

Crunchbase Website Twitter Facebook Linkedin

River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

Kraken

NuCypher

Crunchbase Website Twitter Facebook Linkedin

NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

Kraken

SKALE Labs

Crunchbase Website Twitter Facebook Linkedin

SKALE Labs is a blockchain scalability platform that provides high speed consensus and empowers dApps to run smart contracts.

Kraken

CERE Network

Crunchbase Website Twitter Facebook Linkedin

CERE Network is a blockchain customer relationship management startup.

Kraken

Chronicled

Crunchbase Website Twitter Facebook Linkedin

Chronicled builds trust and automation in the life science industry, powered by blockchain

Kraken

CoinTracker

Crunchbase Website Twitter Facebook Linkedin

CoinTracker is a portfolio and tax manager for cryptocurrency.

Kraken

Securitize

Crunchbase Website Twitter Facebook Linkedin

Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

Kraken

Kava Labs

Crunchbase Website Twitter Facebook Linkedin

Kava Labs is a developer of Kava, is the most trusted DeFi platform by financial institutions

Kraken

Digital Finance Group

Crunchbase Website Twitter Facebook Linkedin

Diversified investment group that manages $1B in digital & blockchain assets across multiple funds, an incubator and global projects

Kraken

Quantstamp

Crunchbase Website Twitter Facebook Linkedin

Leaders in Blockchain Security

Kraken

MakersPlace

Crunchbase Website Twitter Facebook Linkedin

MakersPlace is an authentic and unique digital creation platform powered by blockchain technology for digital creators.

Kraken

Nebula Genomics

Crunchbase Website Twitter Facebook Linkedin

Nebula Genomics leverages blockchain technology to eliminate middlemen and empower people to own their personal genomic data.

Kraken

Akash Network

Crunchbase Website Twitter Facebook Linkedin

Akash Network, the world’s first decentralized and open-source cloud.

Kraken

High Fidelity

Crunchbase Website Twitter Facebook Linkedin

High Fidelity is an open source software for shared virtual reality.

Kraken

i2Chain

Crunchbase Website Twitter Facebook Linkedin

i2Chain is a SaaS platform that secures information and delivers privacy compliant clouds, folders, and files.

Kraken

Dock

Crunchbase Website Twitter Facebook Linkedin

Making it simple for organizations to build, manage and present instantly verifiable digital credentials.

Kraken

Omniex

Crunchbase Website Twitter Facebook Linkedin

Omniex develops software infrastructure that integrates front, middle, and back-office services to simplify access and remove fragmentation.

Kraken

Alchemy

Crunchbase Website Twitter Facebook Linkedin

Alchemy is a developer platform that helps companies to build reliable decentralized applications.

Kraken

Reflexer Labs

Crunchbase Website Twitter Facebook Linkedin

Reflexer Labs is a new decentralized finance project aimed at softening volatility.

Kraken

Coinbase Ventures

Crunchbase Website Twitter Facebook Linkedin

Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

Kraken

CryptiSwap

Crunchbase Website Twitter Facebook Linkedin

CryptiSwap© is a Non-Custodial CryptoCurrency exchange/swap service | no registration | no holds | no third party

Kraken

Iron Fish

Crunchbase Website Twitter Facebook Linkedin

Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

Kraken

Sifchain Finance

Crunchbase Website Twitter Facebook Linkedin

Sifchain is the world’s first omni-chain decentralized exchange (DEX) for digital assets.

Kraken

Rare Bits

Crunchbase Website Twitter Facebook Linkedin

Rare Bits is a zero-fee peer-to-peer marketplace to buy, sell, and discover crypto goods.

Kraken

Snowball Money

Crunchbase Website Twitter Facebook Linkedin

Snowball Money operates as a crypto investment automation platform that provides access to professionally curated portfolios.

Kraken

Saddle Finance

Crunchbase Website Twitter Facebook Linkedin

Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

Kraken

GlobaliD

Crunchbase Website Twitter Facebook Linkedin

Create and manage your own portable, digital identity with globaliD.

Kraken

Zerion

Crunchbase Website Twitter Facebook Linkedin

Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

Kraken

Sommelier

Crunchbase Website Twitter Facebook Linkedin

The new coprocessor for Ethereum. Move your DeFi assets into higher yields faster and cheaper.

Kraken

Agoric

Crunchbase Website Twitter Facebook Linkedin

Agoric provides a framework for programming smart contracts securely and with ease, beyond anything available today.

Kraken

Sperax

Crunchbase Website Twitter Facebook Linkedin

Sperax builds the most secure and scalable infrastructure for decentralized financial services.

Kraken

Polkaswitch

Crunchbase Website Twitter Facebook Linkedin

A decentralized multi-chain liquidity protocol on Polkadot, Ethereum, and top layer 1 & 2 blockchains.

Kraken

AnchorUSD

Crunchbase Website Twitter Facebook Linkedin

AnchorUSD offers stable currency anchored 1-for-1 to the US dollar (USDX).

Kraken

Slingshot Finance

Crunchbase Website Twitter Facebook Linkedin

Next-gen decentralized trading platform

Kraken

TokenSoft

Crunchbase Website Twitter Facebook Linkedin

TokenSoft is a technology and security platform that automates the asset management and fundraising experience.

Kraken

Multis

Crunchbase Website Twitter Facebook Linkedin

Multis provides financial services for companies holding euros, dollars, and cryptocurrencies.

Kraken

Blocknative

Crunchbase Website Twitter Facebook Linkedin

Real-time blockchain transaction management and monitoring.

Kraken

Anchorage

Crunchbase Website Twitter Facebook Linkedin

Anchorage is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

Kraken

District0x

Crunchbase Website Twitter Facebook Linkedin

District0x is a network of decentralized markets and communities.

Kraken

Chain

Crunchbase Website Twitter Facebook Linkedin

Chain built cryptographic ledger systems to make financial services smarter, more secure, and more connected.

Kraken

Provenance Blockchain

Crunchbase Website Twitter Facebook Linkedin

Provenance Blockchain combines the distributed, trustless, and immutable characteristics of blockchain.

Kraken

Beenest

Crunchbase Website Twitter Facebook Linkedin

Beenest is a home sharing platform for hosts to list their homes and for guests to find accommodations.

Kraken

Risk Harbor

Crunchbase Website Twitter Facebook Linkedin

The only objective risk management marketplace for decentralized finance (DeFi).

Kraken

Unum ID

Crunchbase Website Twitter Facebook Linkedin

Unum ID provides sharified — shared, verified — identity, helping companies to instantly know who is who online.

Kraken

Linen App

Crunchbase Website Twitter Facebook Linkedin

New experience that allows our members to earn high yield on their cash.

Kraken

Wilder World

Crunchbase Website Twitter Facebook Linkedin

Wilder World is a decentralized NFT market and artist guild.

Kraken

Round Finance Inc.

Crunchbase Website Twitter Facebook Linkedin

Building an aggregator of digital assets and experiences

Kraken

Aikon

Crunchbase Website Twitter Facebook Linkedin

Aikon provides API-based Blockchain as a Service for top public blockchains including EOS, Ethereum and Libra

Kraken

Jointer

Crunchbase Website Twitter Facebook Linkedin

World’s first COMMERCIAL REAL ESTATE BACKED DeFi

Kraken

Geer™

Crunchbase Website Twitter Facebook Linkedin

Premier NFTs platform for blue-chip brands

Kraken

Metaverse AI

Crunchbase Website Twitter Facebook Linkedin

Bridging Web 3.0, VR/AR & the Metaverse

Kraken

Stream Token

Crunchbase Website Twitter Facebook Linkedin

Stream is a blockchain-based token that allows livestreamers to accept payments with low transaction fees and no platform lock-in.

Kraken

Abacus

Crunchbase Website Twitter Facebook Linkedin

Abacus streamlines customer onboarding for financial services companies.

Kraken

Arise Travel

Crunchbase Website Twitter Facebook Linkedin

Modern infrastructure for the travel industry.

Kraken

RocketFuel

Crunchbase Website Twitter Facebook Linkedin

RocketFuel is a global provider of 1-click payment option using Bitcoin & other cryptocurrencies with no card & bank fees & chargeback costs

Kraken

SureRemit

Crunchbase Website Twitter Facebook Linkedin

SureRemit is an ecosystem for global non-cash remittances.

Kraken

gumi Cryptos Capital (gCC)

Crunchbase Website Twitter Facebook Linkedin

gumi Cryptos Capital is a blockchain and cryptographic asset venture fund

Kraken

CrowdForce

Crunchbase Website Twitter Facebook Linkedin

CrowdForce is an offline distribution network for market research and financial services.

Kraken

Alluva

Crunchbase Website Twitter Facebook Linkedin

Alluva is a blockchain-based, contributor-model product that incentivises participants for their predictions and ratings.

Kraken

Yours

Crunchbase Website Twitter Facebook Linkedin

Yours is a blockchain-based social network where users can earn bitcoin.

Kraken

DCEX

Crunchbase Website Twitter Facebook Linkedin

DCEX is a US based digital currency exchange with OTC desk, digital dollar DCEX$ and a Digital currency news site

Kraken

Bodhi

Crunchbase Website Twitter Facebook Linkedin

Bodhi is a decentralized prediction market platform focusing on Chinese market.

Kraken

Wivity Inc.

Crunchbase Website Twitter Facebook Linkedin

Distributed database that holds security-critial information on cyrptographic private keys. Standardized by the SunSpec Alliance.

Kraken

Audius

Crunchbase Website Twitter Facebook Linkedin

Audius is creating a fully decentralized community of artists, developers, and listeners collaborating to share and defend music.

Kraken

Layer1

Crunchbase Website Twitter Facebook Linkedin

Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

Kraken

NEAR Protocol

Crunchbase Website Twitter Facebook Linkedin

NEAR Protocol is a blockchain designed to provide the performance and UX to get to mainstream adoption of decentralized applications

Kraken

Chainlink Labs

Crunchbase Website Twitter Facebook Linkedin

Chainlink Labs provides open-source blockchain oracle solutions and specializes in the development and integration of chainlink.

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