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101 Top San Francisco Blockchain Companies and Startups of 2021

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This article showcases our top picks for the best San Francisco based Blockchain companies. These startups and companies are taking a variety of approaches to innovating the Blockchain industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top San Francisco Blockchain Startups

Data sourced from Crunchbase and SemRush.

Ripple

Ripple

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Ripple provides one frictionless experience to send money globally using the power of blockchain.

Kraken

Kraken

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Kraken is a cryptocurrency exchange that provides spot and futures trading between Bitcoin, Ethereum and 40+ other digital assets.

Kraken

Figure

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Figure is a financial services company leveraging blockchain technology.

QuarkChain

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QuarkChain is a flexible, scalable, and user-oriented blockchain infrastructure by applying blockchain sharding technology. QuarkChain has proved its advanced technology and brought impact in the industry over years.

Kraken

Bitwise

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Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Kraken

Coinbase

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Coinbase is an online platform that allows merchants, consumers, and traders to transact with digital currency.

Kraken

Uphold

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Uphold is a digital wallet and trading platform that enables cryptocurrencies and other assets affordable and accessible for everyone.

Kraken

Solana

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Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

Kraken

TRM Labs

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TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

Kraken

dYdX

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dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

Kraken

Helium

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Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

Kraken

Stellar Development Foundation

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A non-profit organization that supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

Kraken

Okcoin

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One of the world’s largest cryptocurrency exchanges, Okcoin is building an inclusive future of finance for all.

Kraken

Forte

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We’re building economic technology for games using blockchain.

Kraken

Bitski

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Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

Kraken

Brave

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Brave Software focuses on increasing browsing speed and safety for users, while growing ad revenue share for content creators.

Kraken

Veem

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Veem is a payment service provider that helps simplify the way businesses send and receive funds.

Kraken

Chia Network

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Chia Network is building a blockchain platform based on Proofs of Space and Time.

CoinList

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CoinList provides a platform for digital asset companies to run their token sales.

Kraken

Set Labs

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Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

Kraken

Compound

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Compound is an open-source interest rate protocol that unlocks new financial applications.

Kraken

Celo

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Celo is an open platform that makes financial tools accessible to anyone with a mobile phone.

Kraken

Ankr

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Ankr is a Web3-native infrastructure platform.

Kraken

Rally

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Rally provides a blockchain platform for the development of video streaming and gaming apps.

Kraken

TrustToken

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TrustToken is a platform to create asset-backed tokens that can be used for buying and selling around the world.

Kraken

Oasis Labs

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Oasis Labs is a privacy-first cloud computing platform on blockchain technology.

Kraken

Unstoppable Domains

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Unstoppable Domains launches domains secured by blockchains and builds uncensorable websites.

Kraken

Proxy

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Proxy provides a smartphone-enabled digital identity that allows the user to authenticate and interact with all devices.

Kraken

Harbor

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Harbor is helping to power the next big wave in capital markets – tokenized securities – by automating regulatory compliance.

Kraken

O(1) Labs

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O(1) Labs is a software development company working on Mina Protocol, a tiny, portable blockchain.

Kraken

0x

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0x is an open protocol that enables peer-to-peer trading of assets.

Kraken

Aleo

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Aleo is building the world’s leading developer platform for enabling absolute privacy on blockchains.

Kraken

Numerai

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Numerai transforms and regularizes financial data into machine learning problems for global network of data scientists.

Kraken

Civic

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Civic is a blockchain based ecosystem gives businesses and individuals the tools to control and protect identities.

Kraken

Origin Protocol

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Origin Protocol is a blockchain platform for building decentralized marketplaces.

Kraken

River Financial

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River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

Kraken

NuCypher

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NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

Kraken

SKALE Labs

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SKALE Labs is a blockchain scalability platform that provides high speed consensus and empowers dApps to run smart contracts.

Kraken

CERE Network

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CERE Network is a blockchain customer relationship management startup.

Kraken

Chronicled

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Chronicled builds trust and automation in the life science industry, powered by blockchain

Kraken

CoinTracker

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CoinTracker is a portfolio and tax manager for cryptocurrency.

Kraken

Securitize

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Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

Kraken

Kava Labs

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Kava Labs is a developer of Kava, is the most trusted DeFi platform by financial institutions

Kraken

Digital Finance Group

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Diversified investment group that manages $1B in digital & blockchain assets across multiple funds, an incubator and global projects

Kraken

Quantstamp

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Leaders in Blockchain Security

Kraken

MakersPlace

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MakersPlace is an authentic and unique digital creation platform powered by blockchain technology for digital creators.

Kraken

Nebula Genomics

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Nebula Genomics leverages blockchain technology to eliminate middlemen and empower people to own their personal genomic data.

Kraken

Akash Network

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Akash Network, the world’s first decentralized and open-source cloud.

Kraken

High Fidelity

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High Fidelity is an open source software for shared virtual reality.

Kraken

i2Chain

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i2Chain is a SaaS platform that secures information and delivers privacy compliant clouds, folders, and files.

Kraken

Dock

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Making it simple for organizations to build, manage and present instantly verifiable digital credentials.

Kraken

Omniex

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Omniex develops software infrastructure that integrates front, middle, and back-office services to simplify access and remove fragmentation.

Kraken

Alchemy

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Alchemy is a developer platform that helps companies to build reliable decentralized applications.

Kraken

Reflexer Labs

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Reflexer Labs is a new decentralized finance project aimed at softening volatility.

Kraken

Coinbase Ventures

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Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

Kraken

CryptiSwap

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CryptiSwap© is a Non-Custodial CryptoCurrency exchange/swap service | no registration | no holds | no third party

Kraken

Iron Fish

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Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

Kraken

Sifchain Finance

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Sifchain is the world’s first omni-chain decentralized exchange (DEX) for digital assets.

Kraken

Rare Bits

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Rare Bits is a zero-fee peer-to-peer marketplace to buy, sell, and discover crypto goods.

Kraken

Snowball Money

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Snowball Money operates as a crypto investment automation platform that provides access to professionally curated portfolios.

Kraken

Saddle Finance

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Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

Kraken

GlobaliD

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Create and manage your own portable, digital identity with globaliD.

Kraken

Zerion

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Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

Kraken

Sommelier

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The new coprocessor for Ethereum. Move your DeFi assets into higher yields faster and cheaper.

Kraken

Agoric

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Agoric provides a framework for programming smart contracts securely and with ease, beyond anything available today.

Kraken

Sperax

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Sperax builds the most secure and scalable infrastructure for decentralized financial services.

Kraken

Polkaswitch

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A decentralized multi-chain liquidity protocol on Polkadot, Ethereum, and top layer 1 & 2 blockchains.

Kraken

AnchorUSD

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AnchorUSD offers stable currency anchored 1-for-1 to the US dollar (USDX).

Kraken

Slingshot Finance

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Next-gen decentralized trading platform

Kraken

TokenSoft

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TokenSoft is a technology and security platform that automates the asset management and fundraising experience.

Kraken

Multis

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Multis provides financial services for companies holding euros, dollars, and cryptocurrencies.

Kraken

Blocknative

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Real-time blockchain transaction management and monitoring.

Kraken

Anchorage

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Anchorage is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

Kraken

District0x

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District0x is a network of decentralized markets and communities.

Kraken

Chain

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Chain built cryptographic ledger systems to make financial services smarter, more secure, and more connected.

Kraken

Provenance Blockchain

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Provenance Blockchain combines the distributed, trustless, and immutable characteristics of blockchain.

Kraken

Beenest

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Beenest is a home sharing platform for hosts to list their homes and for guests to find accommodations.

Kraken

Risk Harbor

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The only objective risk management marketplace for decentralized finance (DeFi).

Kraken

Unum ID

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Unum ID provides sharified — shared, verified — identity, helping companies to instantly know who is who online.

Kraken

Linen App

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New experience that allows our members to earn high yield on their cash.

Kraken

Wilder World

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Wilder World is a decentralized NFT market and artist guild.

Kraken

Round Finance Inc.

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Building an aggregator of digital assets and experiences

Kraken

Aikon

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Aikon provides API-based Blockchain as a Service for top public blockchains including EOS, Ethereum and Libra

Kraken

Jointer

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World’s first COMMERCIAL REAL ESTATE BACKED DeFi

Kraken

Geer™

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Premier NFTs platform for blue-chip brands

Kraken

Metaverse AI

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Bridging Web 3.0, VR/AR & the Metaverse

Kraken

Stream Token

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Stream is a blockchain-based token that allows livestreamers to accept payments with low transaction fees and no platform lock-in.

Kraken

Abacus

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Abacus streamlines customer onboarding for financial services companies.

Kraken

Arise Travel

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Modern infrastructure for the travel industry.

Kraken

RocketFuel

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RocketFuel is a global provider of 1-click payment option using Bitcoin & other cryptocurrencies with no card & bank fees & chargeback costs

Kraken

SureRemit

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SureRemit is an ecosystem for global non-cash remittances.

Kraken

gumi Cryptos Capital (gCC)

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gumi Cryptos Capital is a blockchain and cryptographic asset venture fund

Kraken

CrowdForce

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CrowdForce is an offline distribution network for market research and financial services.

Kraken

Alluva

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Alluva is a blockchain-based, contributor-model product that incentivises participants for their predictions and ratings.

Kraken

Yours

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Yours is a blockchain-based social network where users can earn bitcoin.

Kraken

DCEX

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DCEX is a US based digital currency exchange with OTC desk, digital dollar DCEX$ and a Digital currency news site

Kraken

Bodhi

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Bodhi is a decentralized prediction market platform focusing on Chinese market.

Kraken

Wivity Inc.

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Distributed database that holds security-critial information on cyrptographic private keys. Standardized by the SunSpec Alliance.

Kraken

Audius

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Audius is creating a fully decentralized community of artists, developers, and listeners collaborating to share and defend music.

Kraken

Layer1

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Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

Kraken

NEAR Protocol

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NEAR Protocol is a blockchain designed to provide the performance and UX to get to mainstream adoption of decentralized applications

Kraken

Chainlink Labs

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Chainlink Labs provides open-source blockchain oracle solutions and specializes in the development and integration of chainlink.

Written by Mark Smith

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