Mark Smith
This article showcases our top picks for the best San Francisco Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top San Francisco Biotechnology Startups
Data sourced from Crunchbase and SemRush.
Benchling
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Benchling is a cloud-based software platform for biology researchers and research and development organizations.
Twist Bioscience
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Twist Bioscience is a synthetic DNA production for specialty chemical compounds and drug development.
Invitae
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Invitae is a medical genetics company that bring comprehensive genetic information into mainstream medicine to improve healthcare.
Engine Biosciences
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Engine Biosciences is a biotech company that applies machine learning to genomics for drug discovery.
Vir Biotechnology
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Vir Biotechnology is a clinical-stage immunology company developing therapeutic products to treat and prevent serious infectious diseases.
Circle Pharma
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Circle Pharma is a provider of a macrocycle development platform intended to provide macrocyclic peptides.
Aizon
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Aizon is a cloud-based SaaS platform that helps optimize industrial processes in biotech and pharma.
PicnicHealth
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PicnicHealth helps patients easily access their medical records and gives them the opportunity to contribute data to medical research.
Mammoth Biosciences
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Mammoth Biosciences develops novel CRISPR applications for disease detection, research, agriculture, biodefense, and more.
Bluestar Genomics
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Bluestar Genomics delivers epigenomic and big data approaches to reinvent non-invasive molecular diagnostic testing.
Vineti
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Vineti is a commercial cloud-based platform that expands patient access to life-saving cells and gene therapies.
Alector
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Alector is combining state-of-the-art antibody technology and recent discoveries in neuroimmunology and human genetics to develop novel.
FibroGen
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FibroGen, a research-based biotech firm, uses its expertise CTGF and HIF biology to discover, develop, and commercialize novel therapeutics.
Denali Therapeutics
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Denali Therapeutics is a biotechnology company.
Mission Bio
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Mission Bio develops only single-cell multi-omics platform integrating genotype and phenotype for cancer research and biomarker development.
Pendulum Therapeutics
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Pendulum Therapeutics is a biotechnology company improving health through products targeting the microbiome.
Codiak Biosciences
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Codiak is a clinical-stage biopharmaceutical company focused on pioneering the development of exosome-based therapeutics.
Verge Genomics
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Verge Genomics uses machine learning and human genomics to accelerate drug discovery
Vaxart
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Vaxart is a biotechnology company that develops vaccine technology for the treatment of infectious diseases.
Better Therapeutics
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Better develops prescription software for treating cardiometabolic diseases.
Brightseed
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Brightseed features artificial intelligence that reveals powerful compounds hidden in nature.
Chronicled
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Chronicled builds trust and automation in the life science industry, powered by blockchain
Nurix Therapeutics
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Nurix develops small molecule inhibitors for the treatment of proliferative and degenerative diseases.
Brii Biosciences
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Brii Biosciences is a biotechnology company that commits to bring innovative medicines to China as a way to improve public health.
Miroculus
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Miroculus is a hands off sample-to-answer solution for molecular testing.
BlackThorn Therapeutics
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BlackThorn Therapeutics is a clinical-stage neurobehavioral health company pioneering the next generation of artificial intelligence.
Wildtype
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Wildtype is an agtech platform that aims to create clean fish and meat.
Nebula Genomics
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Nebula Genomics leverages blockchain technology to eliminate middlemen and empower people to own their personal genomic data.
Global Blood Therapeutics
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GBT is a clinical-stage biopharmaceutical company developing its lead product candidate, voxelotor, as a therapy for sickle cell disease.
Darmiyan
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Darmiyan is developing an AI-powered software platform for early detection, monitoring, and stratification of Alzheimer’s disease
Aligos Therapeutics
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Aligos Therapeutics is discovering and developing new classes of molecules that interact directly with disease-causing modalities.
Profusa
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PROFUSA is a medical devices company creating tissue-integrated sensors for chronic disease management and healthy living.
Ossium Health
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Ossium Health is building the world’s first bone marrow bank to treat blood cancers
Olema Oncology
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Olema Oncology is a preclinical biotechnology company that develops new drugs for the treatment and prevention of breast cancer.
Spruce Biosciences
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Spruce Biosciences is a biopharmaceutical company that focuses on developing therapies for rare diseases that targets endocrine system.
ALX Oncology
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ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.
Audentes Therapeutics
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Audentes is a biotechnology company that employs gene therapy technology to develop treatments for people with rare muscle diseases.
Five Prime Therapeutics
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FivePrime is a clinical-stage biotechnology company that develops treatments for cancers.
Artemys Foods
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Artemys Foods works on the next generation of meat alternatives by cultivating meat, instead of harvesting meat from animals.
Frontier Medicines
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Frontier Medicines is a developer of a chemoproteomics platform intended to further accelerate the path to drug discovery.
Feel
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Feel provides continuous monitoring and real-time personalized interventions for individuals that suffer from anxiety and depression.
Second Genome
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Second Genome offers a pipeline of microbiome modulators that impact infection, immunity and metabolic diseases.
Tenaya Therapeutics
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Tenaya Therapeutics is a developer of novel therapies designed to offer treatment for heart disease.
Asher Bio
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Asher Bio is a biotechnology company that specializes in the fields of therapeutics builds better immunotherapy for cancer.
Soteria Biotherapeutics
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Soteria is a biotechnology company that develops immunotherapies to treat cancer patients
89bio
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89Bio is a biopharmaceutical company building a pipeline of biologic and small molecule treatments for liver and metabolic disorders.
Turnstone Biologics
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Turnstone Biologics is a privately-held clinical stage biotech company.
Attralus
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Attralus is a biopharmaceutical company focusing on creating transformative medicines to improve the lives of patients.
Pheronym
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Pheronym is creating an all-natural highly effective insect control for agriculture.
Headlands Research
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Headlands Research is a globally integrated clinical trial site organization with a mission to improve the clinical trials process.
Celevity
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Celevity is a seed-stage company that develops drugs to help dogs live longer, healthier lives.
Prellis Biologics
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Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation.
Biome Makers
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Biome Makers is specialized in microbiome understanding to provide comprehensive analysis for agricultural and industrial processes.
Mantra Bio
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Mantra Bio is the creator of REVEAL, an exosome engineering platform combining computational biology and lab automation.
Phylagen
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Phylagen is digitizing the global microbiome to create a more transparent world
Enveda Biosciences
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Enveda Biosciences is a biotechnology company building new medicines from plants.
Orchid
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Orchid is a reproductive technology startup that is capable of detecting rare genetic disorders.
Invuity
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Invuity develops illumination and visualization products for minimally invasive surgical field applications.
LevitasBio
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LevitasBio is is advancing science and human health by providing researchers with a new and powerful method of cellular analysis.
Mekonos Inc.
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Building the Future of Cell Therapies on a Chip
ZBiotics
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ZBiotics is a synthetic biology company that bioengineers probiotic bacteria for nutraceutical and other applications.
System1 Biosciences
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System1 Biosciences is a neurotherapeutics company.
Cofactor Genomics
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Using Predictive Immune Modeling and RNA, Cofactor Genomics builds multidimensional models of disease to deliver true precision medicine.
Neurona Therapeutics
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Neurona Therapeutics is a provider of cell-based medicines dealing with neurological disorders.
goBalto
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GoBalto is a software platform that develops cloud-based solutions for drug trial sponsors and clinical research organizations.
University of California, San Francisco
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Director of the Lab for Advanced Cytometry (LAC) and the Sony Biotechnology Center at UCSF in the Department of Laboratory Medicine
Shasqi
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Shasqi develops cancer treatment intended to use bio-orthogonal chemistry for localized drug delivery.
Amgen Ventures
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Amgen Ventures is a California-based investment firm focused on early- and late-stage biotechnology companies.
PipelineRx
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PipelineRx is a clinical telepharmacy services company that offers clinical telepharmacist teams to its hospital clients.
Tempest Therapeutics
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Tempest Therapeutics is a biotechnology company that focuses on small molecule therapeutics that modulate anti-tumor pathways.
Endogena Therapeutics
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Endogena Therapeutics is a biotech company that develops endogenous regenerative medicines to repair and regenerate tissues and organs.
CASPR Biotech
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CASPR Biotech develops a CRISPR-based platform for molecular detection.
PostEra
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Medicinal Chemistry as a Service powered by Machine Learning
Channel Medsystems
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Channel Medystems is a clinical-stage medical technology engaged in the development of proprietary cryo-ablation delivery technologies.
AcertaPharma
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Acerta Pharma provides drug discovery and development services for oncology and autoimmune diseases.
Perlara
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Perlara, PBC is precision drug discovery that leaves no mutation behind.
Meissa Vaccines
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Meissa Vaccines is a pharmaceutical company focused on advancement of unmet vaccines against viruses that cause serious human diseases.
BioQ Pharma
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BioQ Pharma is a late stage specialty pharmaceutical company focused on developing.
Zephyr Health
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Zephyr Health operates as an insights-as-a-service solution built specifically for life sciences companies.
Coral Genomics
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harnessing diverse human biology to improve drug effectiveness and prior auth
AmbAgon Therapeutics
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AmbAgon Therapeutics is a developer of cancer molecule therapeutics.
Siolta Therapeutics
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Siolta Therapeutics is a developer of human microbiome therapeutics intended to prevent and treat inflammatory diseases.
Aeovian Pharmaceuticals
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Aeovian Pharmaceuticals aims to discover, develop, and commercialize therapeutics for the treatment of rare and age-related diseases.
Actym
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Actym is a biotechnology company that focuses on developing an immuno-oncology platform.
Cleave Therapeutics
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Cleave Therapeutics is focused on protein homeostasis and stress pathways in cancer and neurodegeneration.
Ligandal
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Ligandal is creating cell-specific delivery systems for gene editing tools such as CRISPR using automation and peptide-based nanoparticles.
Slope.io
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Slope.io is a provider of a healthcare software designed to offer an easy way to prevent inventory outages.
Carmot Therapeutics
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Carmot Therapeutics develops drugs to treat inflammatory, metabolic and neurological diseases.
Fountain Therapeutics
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Fountain Therapeutics is discovering and developing treatments for aging-associated diseases.
Xcell Biosciences
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Next generation development and manufacturing platform for enhanced cell therapy performance
Indee Labs
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Indee Labs is unlocking gene-modified cell therapy for the masses with scalable hardware for gene delivery.
Renewal Mill
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Renewal Mill is a next generation ingredients company that upcycles byproducts from food manufacturing into high-quality ingredients.
McKesson
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McKesson distributes medical supplies, information technology, and care management products and services.
Scribe Biosciences
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Flexible tools for single cell analysis
Huue
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Tinctorium is a provider of indigo dyeing solutions intended to reduce chemical usage in the denim supply chain.
Kuleana
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Kuleana creates plant-based alternatives for people’s seafood favorites.
Naked Biome
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Naked Biome is a microbiome-based therapeutics company, launching advanced therapies to treat and prevent skin disease.
Virus Geeks Inc.
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SaaS, Mobile App, BioHealth, Information Technology
Ionetix
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Ionetix is a pioneering end-to-end radiopharmaceutical provider for cardiac PET imaging.
