Best Startup
This article showcases our top picks for the best Massachusetts based Pharmaceutical companies. These startups and companies are taking a variety of approaches to innovating the Pharmaceutical industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top Massachusetts Pharmaceutical Startups
Data sourced from Crunchbase and SemRush.
Pear Therapeutics
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Pear Therapeutics is a software-based digital therapeutics platform designed to treat disease and enhance the efficacy of pharmaceuticals.
EQRx
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EQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.
Pyxis Oncology
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Pyxis Oncology is a developer of antibody therapeutics intended to promote the body’s immune response to cancer.
Centessa Pharmaceuticals
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Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process.
nference
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nference.inc, provides an AI based software platform that synthesizes siloed biomedical knowledge for insights and makes it computable.
Moderna Therapeutics
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Moderna Therapeutics is a biotechnology company that specializes in drug discovery and drug development based on messenger RNA.
Stealth BioTherapeutics
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Stealth BioTherapeutics is a clinical-stage biotechnology company focused on the discovery and commercialization of novel therapies.
Exo Therapeutics
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Exo Therapeutics is a small molecule drug discovery and development company.
Acceleron Pharma
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Acceleron is a biopharmaceutical company engaged in developing, manufacturing and commercializing novel biotherapeutics.
ConcertAI
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ConcertAI is an AI-powered SaaS data company in healthcare that develops medical research tool in oncology.
Axial Therapeutics
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Axial Therapeutics is a clinical stage biopharmaceutical company harnessing the gut-brain axis to develop novel Central Nervous System.
TetraScience
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TetraScience is an R&D cloud data management company that empowers transformation in life sciences and drug discovery.
Bluebird Bio
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Bluebird Bio offers products based on the transformative potential of gene therapy for patients with genetic and orphan diseases.
Repligen
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Repligen is a biopharmaceutical company developing consumable products for the manufacture of biological drugs.
Obsidian Therapeutics
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Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
Charles River Laboratories International
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Charles River Laboratories International provides research models, and outsourced preclinical services for the accelerated R&D of drugs
Quanterix
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Quanterix is a platform for single molecule analysis that supports clinical diagnostics, drug development, and life science researches.
Stoke Therapeutics
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Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for the treatment.
Seven Bridges
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Seven Bridges is the leading biomedical data science company.
XtalPi
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XtalPi is a biotech firm that uses artificial intelligence and computing to accelerate the development of new pharmaceutical drugs.
Amylyx Pharmaceuticals
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Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain.
PillPack
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PillPack is a full-service pharmacy that sorts medication by dose and offers door-to-door delivery.
TScan Therapeutics
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TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.
Alnylam Pharmaceuticals
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Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
Cerevel Therapeutics
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Cerevel Therapeutics is a biopharmaceutical company.
Lyndra Therapeutics
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Lyndra Therapeutics is a novel technology platform reinventing medicine for a healthier world.
4G Clinical
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4G Clinical provides software and services for clinical drug trials specifically in randomization and trial supply management (RTSM).
TriNetX
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TriNetX is the global health research network that revolutionizes clinical research
Dyne Therapeutics
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Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.
Apellis Pharmaceuticals
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Apellis Pharmaceuticals focuses on developing novel therapeutics and drug delivery technologies to address chronic inflammatory diseases.
Cellarity
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Cellarity’s platform digitizes the molecular information in cells to elucidate how they behave in health and disease.
Rapid Micro Biosystems
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Rapid Micro Biosystems offers tools that detect microbial contamination in manufacturing pharmaceutical, biotechnology and other products.
Rhythm Pharmaceuticals
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Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
KSQ Therapeutics
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KSQ Therapeutics is using CRISPR technology within a powerful drug discovery engine to enable high-confidence drug development.
Aura Biosciences
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Aura Biosciences is a biotechnology company that focuses on the development of drugs by using tumor targeted pseudovirions.
Qstream
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Qstream is a microlearning platform that quantifiably improves job proficiency and changes behavior that results in teams who excel.
Infinity Pharmaceuticals
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Infinity Pharmaceuticals engages in the discovery and development of medicines for the treatment of cancer and related conditions.
Dicerna Pharmaceuticals
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Dicerna Pharmaceuticals is a biotechnology company involved in the discovery and development of innovative treatments.
Adagio Therapeutics
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Adagio Therapeutics offers research and development of therapeutic pharmaceuticals related to COVID-19.
Constellation Pharmaceuticals
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Constellation Pharmaceuticals develops drugs in the field of epigenetics focusing on selective regulators of its function.
Rubius Therapeutics
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Rubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.
Axcella
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Axcella is a biotechnology company providing therapeutics development solutions.
Cyteir Therapeutics
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Cyteir is developing the next generation of synthetic lethal therapies to treat cancer.
Ironwood Pharmaceuticals
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Ironwood Pharmaceuticals is an entrepreneurial pharmaceutical company, develops drugs for gastrointestinal and cardiovascular diseases.
Fog Pharmaceuticals
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FogPharma creates a new class of medicines that target human disease drivers currently considered undruggable.
Ultivue
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Ultivue is a biotechnology company that specializes in tissue imaging, diagnostics, and multiplexing.
X4 Pharmaceuticals
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X4 Pharmaceuticals a clinical-stage oncology company developing best-in-class oral small molecule CXCR4 antagonists for the treatment.
Akouos
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Akouos is a biotechnology company focusing on restoring and preserving hearing.
Swoop
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Swoop is a provider of artificial intelligence and machine learning solutions to find, engage, and convert the ideal patient population.
Selecta Biosciences
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Selecta Biosciences is a clinical-stage biotechnology company with an unrelenting commitment to overcoming immunogenicity.
Orna Therapeutics
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Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA (oRNA) therapeutics to treat various diseases
ROME Therapeutics
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ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.
Affinivax
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Affinivax is a biopharmaceutical company developing vaccines used to enhance the depth of protection against infectious diseases.
SmartLabs
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SmartLabs builds and operates enterprise-grade labs, including multi-use R&D labs, vivariums, process development, and manufacturing suites.
Jounce Therapeutics
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Jounce Therapeutics is developing cancer immune-therapies to harness the immune system to attack cancerous cells and tumors.
TCR2
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TCR2 is a discovery stage pharmaceutical company that developed a unique proprietary TRuC™ platform.
Kala Pharmaceuticals
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Kala Pharmaceuticals develops novel treatments for diseases that affect mucosal tissues.
Karyopharm Therapeutics
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Karyopharm Therapeutics is a clinical-stage pharmaceutical company developing drugs for the treatment of cancer and other major diseases.
Syros Pharmaceuticals
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Syros Pharmaceuticals is a life sciences company that focuses on treating diseases by mapping gene regulatory circuits.
Vor Biopharma
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Vor Biopharma is an immuno-oncology company that develops therapies for treating cancer.
Verastem Oncology
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Verastem is a biopharmaceutical company that focuses on discovering and developing novel drugs that selectively target cancer stem cells.
Anji Pharmaceuticals
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Anji Pharmaceuticals is focused on tackling high-value targets validated by human genetics.
Radius Health
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Radius Health develops drug therapies for osteoporosis and women’s health.
Arrakis Therapeutics
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Arrakis Therapeutics is a biopharmaceutical developing drugs for neurological disorders and other diseases.
RxAdvance
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RxAdvance, a national full service PBM, leverages disruptive Collaborative PBM Cloud™ to manage standard & specialty drug benefits.
FORMA Therapeutics
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FORMA Therapeutics is a biopharmaceutical company intended for the discovery, development and commercialization of transformative medicines.
Cyclerion Therapeutics
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Cyclerion Therapeutics is a clinical-stage biopharmaceutical company.
Reverie Labs
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Reverie Labs is a machine learning-driven pharma company.
OncXerna Therapeutics
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OncXerna Therapeutics offers precision medicine using an innovative RNA-based biomarker platform.
Keros Therapeutics
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Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.
AVEO Oncology
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AVEO is a biopharmaceutical company that offers drug development strategies for targeted cancer therapeutics.
Deciphera Pharmaceuticals
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Deciphera Pharmaceuticals focuses on improving kinase inhibitor treatments.
Elicio Therapeutics
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Elicio Therapeutics develops an immuno-tumor vaccine to treat cancer.
Q-State Biosciences
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Q-State has developed world-leading technologies and proprietary approaches for probing rare and genetic CNS conditions.
Checkmate Pharmaceuticals
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Checkmate Pharma is a clinical stage biopharmaceutical company developing a new approach for cancer immunotherapy.
Korro Bio
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Korro Bio provides an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms.
Pieris Pharmaceuticals
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Pieris Pharmaceuticals is a clinical-stage biotechnology company applying its proprietary.
Fresenius Medical Care North America
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Fresenius Medical Care North America provides healthcare services to people with renal and other chronic conditions.
Syndax Pharmaceuticals
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Syndax Pharmaceuticals focuses on developing an HDAC inhibitor for solid tumors and hematological tumors.
Clinical Research IO
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Clinical Research IO is a health tech company that offers paper-based clinical trials with software, eSource, CTMS, and eRegulatory.
CardioFocus
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CardioFocus is a biotechnology company that focuses on the advancement of ablation treatments for cardiac disorders.
Palleon Pharmaceuticals
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Palleon Pharmaceuticals is a developer of a biotechnology platform designed to offer glycoimmune checkpoint inhibitors to treat cancer.
Pharmaron
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Pharmaron is a research and development service provider for the pharmaceutical industry.
Bantam Pharmaceutical
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Bantam Pharmaceutical has deep experience in oncology drug discovery and development including R&D and partnering.
Silicon Therapeutics
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Silicon Therapeutics is a fully integrated drug design, research, and development company.
Rational Vaccines
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Rational Vaccines is a pre-clinical stage that develops live-attenuated herpes simplex virus vaccines.
Santi Therapeutics
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Santi Therapeutics is a pharmaceutical company that focuses on the research and development of small molecule therapeutics.
Immuneering
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Immuneering is a bioinformatics company that develops new medicines unlikely to be found by traditional drug discovery methods.
Corbus Pharmaceuticals
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Corbus Pharmaceuticals is a clinical-stage pharmaceutical company focused on treating inflammatory and fibrotic diseases.
TARIS Biomedical
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TARIS Biomedical is a pharmaceutical company developing therapies for genitourinary system issues.
Entasis Therapeutics
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Entasis Therapeutics is developing a portfolio of innovative cures.
Pulmatrix
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Pulmatrix develops inhaled therapies for the treatment, prevention and transmission of infectious and progressive respiratory diseases.
Kernal Biologics
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Kernalbio creates mRNA therapies that instruct specific cells on how to make their own medicine.
Windgap Medical
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WindGap Medical is a biotech company that manufactures medical devices used to treat patients with severe allergies.
Monocl
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Monocl empowers life science professionals with the complete global expert solution for impactful outreach and strategic engagement.
Allena Pharmaceuticals
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Allena Pharmaceuticals develops and commercializes non-systemic protein therapeutics to treat metabolic and orphan diseases.
Lyra Therapeutics
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Lyra Therapeutics is a clinical-stage company developing medicines to treat ear, nose, and throat diseases.
Karuna Therapeutics
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Karuna Therapeutics is a Massachusetts-based developer of drugs for the treatment of schizophrenia.
Azurity Pharmaceuticals
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Azurity Pharmaceuticals is a developer of drug products and technologies to address the needs of patients.
HotSpot Therapeutics
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HotSpot Therapeutics is a developer of a therapy platform designed to discover medicines and provide proper treatment.
