72 Best South Dakota Health Care Companies and Startups

October 3, 2021
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This article showcases our top picks for the best South Dakota based Health Care companies. These startups and companies are taking a variety of approaches to innovating the Health Care industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top South Dakota Health Care Startups

Data sourced from Crunchbase and SemRush.

DocuTAP

DocuTAP

Crunchbase Website Twitter Facebook Linkedin

DocuTAP provides urgent care EMR and practice management software for healthcare providers.

Avera eCare

Avera eCare

Crunchbase Website Twitter Facebook Linkedin

Avera eCARE is the world’s leading telehealth provider

Avera eCare

Primrose Retirement Communities

Crunchbase Website Twitter Facebook Linkedin

Primrose Retirement Communities provides quality independent senior living and assisted living care.

Avera eCare

Avera Medical Group

Crunchbase Website Twitter Facebook Linkedin

Avera Medical Group operates a network of healthcare facilities .

Avera eCare

Immutrix Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Immutrix Therapeutics is a medical tech company that has developed a medical device for cleansing the blood.

Avera eCare

Experity

Crunchbase Website Twitter Facebook Linkedin

Experity is the combination of DocuTAP and Practice Velocity and provides technology solutions.

Avera eCare

CEGA Innovations

Crunchbase Website Twitter Facebook Linkedin

CEGA provides the only product line in the market to incorporate best practices in Safe Patient Handling, every time.

Avera eCare

Carex Health Brands

Crunchbase Website Twitter Facebook Linkedin

Carex Health Brands develops, manufactures and merchandises in-home health consumer products.

Avera eCare

Avera Health Plans

Crunchbase Website Twitter Facebook Linkedin

Affordable health insurance plans in SD and IA for individuals, families, business or Medicare Supplement Insurance.

Avera eCare

Concordance Healthcare Solutions

Crunchbase Website Twitter Facebook Linkedin

Concordance Healthcare Solutions one of the independent, healthcare distributors in the U.S.

Avera eCare

Bridger Healthcare

Crunchbase Website Twitter Facebook Linkedin

Bridger Healthcare is a medical provider that offers long and short term care solutions.

Avera eCare

Monument Health

Crunchbase Website Twitter Facebook Linkedin

Monument Health is a community-based health care system that provides a wide range of treatment and medical services to various patients.

Avera eCare

North American Company for Life and Health Insurance

Crunchbase Website Twitter Facebook Linkedin

North American Company for Life and Health Insurance is an insurance company specializing in businesses and financial protection solutions.

Avera eCare

Black Hills Orthopedic and Spine Center, P.C. Inc

Crunchbase Website Twitter Facebook Linkedin

Black Hills Orthopedic & Spine Center is an orthopaedic health care firm providing expert bone, joint, and muscle care to patients.

Avera eCare

LifeScape LLC

Crunchbase Website Twitter Facebook Linkedin

LifeScape provides Children’s Care Hospital & School and South Dakota Achieve joined together.

Avera eCare

Barton Publishing

Crunchbase Website Twitter Facebook Linkedin

Barton Publishing helps people get off drugs, avoid surgery and experience vibrant health using natural home remedies!

Avera eCare

Regional Health

Crunchbase Website Twitter Facebook Linkedin

An integrated health care system with the purpose of helping patients and communities live well.

Avera eCare

Thubrikar Aortic Valve

Crunchbase Website Twitter Facebook Linkedin

Thubrikar Aortic Valve is a South Dakota-based company that operates in the healthcare sector.

Avera eCare

Fischer, Rounds & Associates Inc.

Crunchbase Website Twitter Facebook Linkedin

Fischer, Rounds & Associates is an insurance company offering commercial, health, and life insurance in South Dakota.

Avera eCare

Horizon Health Care

Crunchbase Website Twitter Facebook Linkedin

Horizon Health Care provides medical, dental and mental health care services.

Avera eCare

DAKOTACARE

Crunchbase Website Twitter Facebook Linkedin

DAKOTACARE is an insurance company providing health and wellness programs.

Avera eCare

Behavior Care Specialists

Crunchbase Website Twitter Facebook Linkedin

Behavior Care Specialists is an outpatient treatment provider of autism spectrum disorder (ASD) services.

Avera eCare

Pivotal Health Solutions

Crunchbase Website Twitter Facebook Linkedin

Pivotal Health Solutions is a Leading provider of technology-driven health and wellness products for chiropractic and the medical industry.

Avera eCare

South Dakota Department of Health

Crunchbase Website Twitter Facebook Linkedin

Department of Health for South Dakota

Avera eCare

Native American Natural Foods

Crunchbase Website Twitter Facebook Linkedin

American Natural Foods provides a category of natural healthy choices in the marketplace that currently does not exist.

Avera eCare

Brookings Health System

Crunchbase Website Twitter Facebook Linkedin

Brookings Health System serves the community with a full range of hospital, outpatient, home health care, and extended care services.

Avera eCare

Neurology Associates, P.C.

Crunchbase Website Twitter Facebook Linkedin

Neurology Associates, P.C. is an independent neurology group based in Sioux Falls, South Dakota.

Avera eCare

Black Hills Surgical Hospital

Crunchbase Website Twitter Facebook Linkedin

Black Hills Surgical Hospital is a surgical & imaging center, among the nation’s best at providing orthopedic, spine & other surgical care.

Avera eCare

Bethany Lutheran Home for the Aged

Crunchbase Website Twitter Facebook Linkedin

Bethany Lutheran Home for the Aged provides skilled nursing care, memory care, and rehabilitation services to area residents.

Avera eCare

Black Hills Works

Crunchbase Website Twitter Facebook Linkedin

Black Hills Works is a non-profit organization that provides transportation, healthcare, and education services.

Avera eCare

Push Pedal Pull

Crunchbase Website Twitter Facebook Linkedin

Push Pedal Pull is a health & wellness company specializing in exercise equipment.

Avera eCare

WellFully

Crunchbase Website Twitter Facebook Linkedin

WellFully is a nonprofit organization that offers inpatient drug rehabilitation and residential behavioral healthcare for adolescents.

Avera eCare

Dakota Financial Services

Crunchbase Website Twitter Facebook Linkedin

Dakota Financial Services offers a spectrum of insurance policies that includes automobile, home, life, health, medicare, farm and business.

Avera eCare

Kota Technology

Crunchbase Website Twitter Facebook Linkedin

Kota Technology is an IT healthcare firm that offers HIPPA compliance, networking, software, dental & ophthalmology practice specialization.

Avera eCare

eProvider Solutions

Crunchbase Website Twitter Facebook Linkedin

Provide electronic solutions for healthcare .

Avera eCare

Rural HealthCare,Inc.

Crunchbase Website Twitter Facebook Linkedin

Rural HealthCare,Inc. is a healthcare provider focus on the rural sector.

Avera eCare

Wapiti Medical Staffing

Crunchbase Website Twitter Facebook Linkedin

Wapiti Medical Staffing is a staffing agency company located in Milbank.

Avera eCare

Happy Tapper

Crunchbase Website Twitter Facebook Linkedin

Happy Tapper is a company which develops lifestyle apps for iPhone & iPad

Avera eCare

Lantis Enterprises Inc

Crunchbase Website Twitter Facebook Linkedin

Lantis Enterprises Inc is a family-oriented health care providing firm.

Avera eCare

Northern Hills Training Center

Crunchbase Website Twitter Facebook Linkedin

Northern Hills Training Center renders residential, vocational, day and medical services for adults with developmental disabilities.

Avera eCare

Creative Surfaces

Crunchbase Website Twitter Facebook Linkedin

Creative Surfaces is a construction firm dealing in counter tops, signage, lockers and fitness centers.

Avera eCare

Jenkins Living Center

Crunchbase Website Twitter Facebook Linkedin

Jenkins Living Center is a non profit organization which specializes in rehab & geriatric services for the elderly & physically challenged.

Avera eCare

XpressRules

Crunchbase Website Twitter Facebook Linkedin

XpressRules provides both security and convenience for managing access to your personal health information.

Avera eCare

Cal Ore Life Flight

Crunchbase Website Twitter Facebook Linkedin

Cal-Ore Life Flight is medical transportation that provides safe, caring ground and air transportation for people in medical emergencies.

Avera eCare

CruiseLT, Inc.

Crunchbase Website Twitter Facebook Linkedin

All-inclusive healthcare cruise line and senior living resorts. The freedom to live the rest of your life on YOUR terms…and in style.

Avera eCare

Aequitas Health

Crunchbase Website Twitter Facebook Linkedin

Aequitas Health was catalyzed by the Aspen Health Innovators Fellowship’s charge to address challenges in the US healthcare ecosystem.

Avera eCare

AQREVA

Crunchbase Website Twitter Facebook Linkedin

AQREVA offers medical billing and revenue cycle-related services.

Avera eCare

Renutra Natural Health Products

Crunchbase Website Twitter Facebook Linkedin

Renutra Natural Health Products share a tradition that runs deeper than individual knowledge, education and expertise.

Avera eCare

Yankton Medical Clinic

Crunchbase Website Twitter Facebook Linkedin

Yankton Medical Clinic and its network of outreach locations are proud to serve residents of South Dakota and Nebraska.

Avera eCare

Ophthalmology

Crunchbase Website Twitter Facebook Linkedin

Ophthalmology provides eye care and healthcare services.

Avera eCare

Clinical Laboratory Of The Black Hills

Crunchbase Website Twitter Facebook Linkedin

Clinical Laboratory Of The Black Hills provides the best possible anatomic pathology services to meet the needs of clients and patients.

Avera eCare

Huron Regional Medical Center

Crunchbase Website Twitter Facebook Linkedin

Huron Regional Medical Center provides general healthcare and surgery services.

Avera eCare

Hauge

Crunchbase Website Twitter Facebook Linkedin

Hauge provides debt collection, cash flow management, revenue cycle improvement and finance management in the healthcare sector.

Avera eCare

PatientX Agency

Crunchbase Website Twitter Facebook Linkedin

PatientX Agency is a company specialized in health care marketing, graphic & web design and advertising services.

Avera eCare

EZUltrasound

Crunchbase Website Twitter Facebook Linkedin

EZUltrasound provides home ultrasound therapy machines.

Avera eCare

AquaBling

Crunchbase Website Twitter Facebook Linkedin

We make products that promote health, eco-conscious living, and individuality.

Avera eCare

Philip Health Services

Crunchbase Website Twitter Facebook Linkedin

Philip Health Services is a non-profit organization that offers primary care, physical therapy, clinic and assisted living services.

Avera eCare

AntiRadical Therapeutics

Crunchbase Website Twitter Facebook Linkedin

AntiRadical Therapeutics focuses on developing drugs for the treatment of blood flow disruption.

Avera eCare

Smiles For Siouxland

Crunchbase Website Twitter Facebook Linkedin

Smilesforsiouxland is a concerned group

Avera eCare

Health Link

Crunchbase Website Twitter Facebook Linkedin

Health Link provides healthcare, point of care exchange, clinical engagement, and clinical event notification services.

Avera eCare

Healthcare Plus Federal Credit Union

Crunchbase Website Twitter Facebook Linkedin

Healthcare Plus Federal Credit Union is a financial institution that provides loans, savings, credit cards and online banking services.

Avera eCare

South Dakota Foundation for Medical Care

Crunchbase Website Twitter Facebook Linkedin

South Dakota Foundation for Medical Care specializes in providing quality development and resource for health care and stakeholders.

Avera eCare

Agape Counseling Center

Crunchbase Website Twitter Facebook Linkedin

Agape Counseling Center is a Certified Academic Institution with the National Christian Counselors Association, providing training.

Avera eCare

FitThumb

Crunchbase Website Twitter Facebook Linkedin

FitThumb is an online web-based wellness platform.

Avera eCare

Krohmer Agency

Crunchbase Website Twitter Facebook Linkedin

Krohmer is an insurance company which offers auto, home, renters, farm, crop, commercial, health & life insurance services.

Avera eCare

Omni Medical Holdings

Crunchbase Website Twitter Facebook Linkedin

Omni Medical Holdings, Inc. provides transcription, billing and collection services to healthcare providers throughout.

Avera eCare

Lifetime Eyecare

Crunchbase Website Twitter Facebook Linkedin

Lifetime Eyecare focuses on providing comprehensive eye care services along with in-demand lenses and frames.

Avera eCare

Youth and Family Services

Crunchbase Website Twitter Facebook Linkedin

Youth & Family Services is a nonprofit organization that provides youth development programs for children and families.

Avera eCare

SIOUX FALLS SPECIALTY HOSPITAL,

Crunchbase Website Twitter Facebook Linkedin

SFSH is committed to meeting the needs of their patients and is the highest-ranking hospital in Sioux Falls in patient satisfaction.

Avera eCare

Dale Animal Hospital

Crunchbase Website Twitter Facebook Linkedin

Dale Animal Hospital is a veterinary company. It provides services like wellness, surgery, critical care, dentistry, and more.

Avera eCare

Cuong Strong Personal Training & Nutrition

Crunchbase Website Twitter Facebook Linkedin

Cuong Strong provides a personal training focusing on form, technique, and exercise execution.

Avera eCare

Madison Regional Health System

Crunchbase Website Twitter Facebook Linkedin

Madison Regional Health System is a non-profit healthcare company that offers radiology, obstetrics, rehab, surgical & outpatient services.

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