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48 Top Minnesota Therapeutics Companies and Startups of 2021

This article showcases our top picks for the best Minnesota based Therapeutics companies. These startups and companies are taking a variety of approaches to innovating the Therapeutics industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Minnesota Therapeutics Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

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Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Inspire Medical Systems

Inspire Medical Systems

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Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

Inspire Medical Systems

Respicardia

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Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

Inspire Medical Systems

EnteroMedics

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EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Inspire Medical Systems

CHF Solutions

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CHF Solutions is a medical device company that focuses on innovative cardiac assist therapy to treat patients.

Inspire Medical Systems

Celcuity

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Celcuity transform care for patients with cancer or autoimmune disease.

Inspire Medical Systems

Cardionomic

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Cardionomic is a medical device developer that treats reduced cardiac output.

Inspire Medical Systems

Marker Therapeutics

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Marker Therapeutics is a clinical-stage developer of a transformative, non-genetically engineered, multi-antigen T cell therapy platform.

Inspire Medical Systems

DiaMedica

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DiaMedica is a biopharmaceutical company focused on developing innovative treatments for stroke.

Inspire Medical Systems

SynerFuse

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SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

Inspire Medical Systems

SpineThera

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SpineThera develops novel, sustained-release, injectable drugs to treat pain.

Inspire Medical Systems

Invenshure

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Invenshure is an incubator firm that invests in therapeutics, emerging platform technologies, and medical devices or imaging companies.

Inspire Medical Systems

Gila Therapeutics

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Gila Therapeutics, Inc. is a privately-held Corporation operating in the state of Florida since January 2014.

Inspire Medical Systems

Insitu Biologics

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InSitu Biologics is a developer of a drug delivery platform designed to focus on development of new and proprietary treatments.

Inspire Medical Systems

Stimdia Medical

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Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

Inspire Medical Systems

OX2 Therapeutics

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OX2 Therapeutics is a healthcare therapeutics company that focuses on treating brain tumors.

Inspire Medical Systems

Celleration

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Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

Inspire Medical Systems

GRIP Molecular Technologies

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GRIP Molecular is a molecular detection device used at point-of-care to enable the rapid identification of chemical and biological threats.

Inspire Medical Systems

Peytant Solutions

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Peytant Solutions is a regenerative medical device company.

Inspire Medical Systems

BRTI Life Sciences

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BRTI Life Sciences concentrates on cell research and therapeutics.

Inspire Medical Systems

Mill Creek Life Sciences

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Mill Creek Life Sciences provides tools and technologies to support the development and application of cellular and biologic therapeutics.

Inspire Medical Systems

Agitated Solutions

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Agitated Solutions operates a healthcare company that delivers microbubble treatment for patients with hypoxemic respiratory failure.

Inspire Medical Systems

Shape Medical Systems

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Shape Medical Systems develops cardiopulmonary exercise testing technology to improve the early detection and treatment of heart failure.

Inspire Medical Systems

Sciadonics

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Sciadonics is a biotech company that commercializes sciadonic acid and related fatty acids to combat their chronic inflammation epidemic.

Inspire Medical Systems

exsulin

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Exsulin Corporation, a therapeutic development company, develops and commercializes drugs for the treatment of type 1 and type 2 diabetes.

Inspire Medical Systems

Bavia Health

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Bavia Health provides aromatherapy and therapeutic massage services to new mothers and surgical patients right in the hospital room.

Inspire Medical Systems

preCARDIA

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preCARDIA is a provider of inpatient partially implantable devices for treating patients with acute decompensated heart failure.

Inspire Medical Systems

Activation Life

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Activation Life offers Sonic Therapy, therapy that utilizes acoustical frequencies to treat neurological and musculoskeletal disorders.

Inspire Medical Systems

Atritech

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Atritech is a private company located in Minneapolis, Minnesota. The company was founded in 2000 and has developed proprietary technology

Inspire Medical Systems

Acuity Medical International

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Acuity Medical International, Inc. develops therapeutic devices and protocols for age related macular degeneration to treat adults

Inspire Medical Systems

Discovery Genomics

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Discovery Genomics, Inc. (DGI) was founded in 2000 and became operational in January 2002.

Inspire Medical Systems

Medisyn Technologies

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Medisyn Technologies develops pre-qualified proprietary drug compounds for breast, renal, prostate, and lung cancer treatments.

Inspire Medical Systems

Exos

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Exos is a medical device company that develops and commercializes thermoformable external musculoskeletal stabilization systems.

Inspire Medical Systems

General Probiotics

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General Probiotics develops innovative cellbots, antimicrobial probiotics that eliminate harmful pathogens in livestock.

Inspire Medical Systems

Kalypto Medical

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Kalypto Medical focuses on expanding the use of Negative Pressure Wound Therapy (NPWT) technology beyond its current reach.

Inspire Medical Systems

Impleo Medical

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Impleo Medical is a developed a proprietary bulking agent therapy for Gastroesophageal Reflux Disease in medical devices

Inspire Medical Systems

Respiratory Sciences

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Respiratory Sciences transforms respiratory care through the expansion of access to care in medical centers and in patient homes.

Inspire Medical Systems

Anatomi

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Anatomi is advancing the fundamental understanding of neurodevelopment and genuine human neural networks.

Inspire Medical Systems

Quench Medical

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Quench Medical is developing a novel aerosol platform technology to deliver medicine into deep areas of the lung.

Inspire Medical Systems

BlueAllele

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BlueAllele is a biotechnology firm that specializes in the development and commercialization of gene editing therapeutics.

Inspire Medical Systems

Children’s Therapy Center

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Children’s Therapy Center specializes in occupational, physical and speech therapy.

Inspire Medical Systems

McFerson Chiropractic

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McFerson Chiropractic provides gentle chiropractic care, soft tissue therapies, and lifestyle coaching services.

Inspire Medical Systems

Denali Medical

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Denali Medical II is a medical device incubator focused on creating new therapies for unmet and/or underserved clinical needs.

Inspire Medical Systems

AneuRx

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AneuRx provides stent-grafts for abdominal aortic aneurysm repair therapy.

Inspire Medical Systems

Acumen Counseling Services

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Acumen Counseling Services provides co-occurring disorder treatment, dialectical behavioral therapy, anxiety, and trauma services.

Inspire Medical Systems

EndoMetabolic Solutions

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EndoMetabolic Solutions develops a medical device for the surgical treatment of obesity.

Inspire Medical Systems

Motion Control Group

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Motion Control Group is a global manufacturer of highly customized motors and motion control solutions for the medical, life sciences.

Inspire Medical Systems

Sleepy Eye Medical Center Hospital

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Sleepy Eye Medical Center Hospital offers healthcare services regarding diabetes, birth, chronic pain, orthopedics and therapy services.

Written by Mark Smith

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