48 Top Minnesota Therapeutics Companies and Startups of 2021

July 6, 2021

This article showcases our top picks for the best Minnesota based Therapeutics companies. These startups and companies are taking a variety of approaches to innovating the Therapeutics industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Minnesota Therapeutics Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

Crunchbase Website Twitter Facebook Linkedin

Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Inspire Medical Systems

Inspire Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

Inspire Medical Systems

Respicardia

Crunchbase Website Twitter Facebook Linkedin

Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

Inspire Medical Systems

EnteroMedics

Crunchbase Website Twitter Facebook Linkedin

EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Inspire Medical Systems

CHF Solutions

Crunchbase Website Twitter Facebook Linkedin

CHF Solutions is a medical device company that focuses on innovative cardiac assist therapy to treat patients.

Inspire Medical Systems

Celcuity

Crunchbase Website Twitter Facebook Linkedin

Celcuity transform care for patients with cancer or autoimmune disease.

Inspire Medical Systems

Cardionomic

Crunchbase Website Twitter Facebook Linkedin

Cardionomic is a medical device developer that treats reduced cardiac output.

Inspire Medical Systems

Marker Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Marker Therapeutics is a clinical-stage developer of a transformative, non-genetically engineered, multi-antigen T cell therapy platform.

Inspire Medical Systems

DiaMedica

Crunchbase Website Twitter Facebook Linkedin

DiaMedica is a biopharmaceutical company focused on developing innovative treatments for stroke.

Inspire Medical Systems

SynerFuse

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SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

Inspire Medical Systems

SpineThera

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SpineThera develops novel, sustained-release, injectable drugs to treat pain.

Inspire Medical Systems

Invenshure

Crunchbase Website Twitter Facebook Linkedin

Invenshure is an incubator firm that invests in therapeutics, emerging platform technologies, and medical devices or imaging companies.

Inspire Medical Systems

Gila Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Gila Therapeutics, Inc. is a privately-held Corporation operating in the state of Florida since January 2014.

Inspire Medical Systems

Insitu Biologics

Crunchbase Website Twitter Facebook Linkedin

InSitu Biologics is a developer of a drug delivery platform designed to focus on development of new and proprietary treatments.

Inspire Medical Systems

Stimdia Medical

Crunchbase Website Twitter Facebook Linkedin

Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

Inspire Medical Systems

OX2 Therapeutics

Crunchbase Website Twitter Facebook Linkedin

OX2 Therapeutics is a healthcare therapeutics company that focuses on treating brain tumors.

Inspire Medical Systems

Celleration

Crunchbase Website Twitter Facebook Linkedin

Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

Inspire Medical Systems

GRIP Molecular Technologies

Crunchbase Website Twitter Facebook Linkedin

GRIP Molecular is a molecular detection device used at point-of-care to enable the rapid identification of chemical and biological threats.

Inspire Medical Systems

Peytant Solutions

Crunchbase Website Twitter Facebook Linkedin

Peytant Solutions is a regenerative medical device company.

Inspire Medical Systems

BRTI Life Sciences

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BRTI Life Sciences concentrates on cell research and therapeutics.

Inspire Medical Systems

Mill Creek Life Sciences

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Mill Creek Life Sciences provides tools and technologies to support the development and application of cellular and biologic therapeutics.

Inspire Medical Systems

Agitated Solutions

Crunchbase Website Twitter Facebook Linkedin

Agitated Solutions operates a healthcare company that delivers microbubble treatment for patients with hypoxemic respiratory failure.

Inspire Medical Systems

Shape Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Shape Medical Systems develops cardiopulmonary exercise testing technology to improve the early detection and treatment of heart failure.

Inspire Medical Systems

Sciadonics

Crunchbase Website Twitter Facebook Linkedin

Sciadonics is a biotech company that commercializes sciadonic acid and related fatty acids to combat their chronic inflammation epidemic.

Inspire Medical Systems

exsulin

Crunchbase Website Twitter Facebook Linkedin

Exsulin Corporation, a therapeutic development company, develops and commercializes drugs for the treatment of type 1 and type 2 diabetes.

Inspire Medical Systems

Bavia Health

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Bavia Health provides aromatherapy and therapeutic massage services to new mothers and surgical patients right in the hospital room.

Inspire Medical Systems

preCARDIA

Crunchbase Website Twitter Facebook Linkedin

preCARDIA is a provider of inpatient partially implantable devices for treating patients with acute decompensated heart failure.

Inspire Medical Systems

Activation Life

Crunchbase Website Twitter Facebook Linkedin

Activation Life offers Sonic Therapy, therapy that utilizes acoustical frequencies to treat neurological and musculoskeletal disorders.

Inspire Medical Systems

Atritech

Crunchbase Website Twitter Facebook Linkedin

Atritech is a private company located in Minneapolis, Minnesota. The company was founded in 2000 and has developed proprietary technology

Inspire Medical Systems

Acuity Medical International

Crunchbase Website Twitter Facebook Linkedin

Acuity Medical International, Inc. develops therapeutic devices and protocols for age related macular degeneration to treat adults

Inspire Medical Systems

Discovery Genomics

Crunchbase Website Twitter Facebook Linkedin

Discovery Genomics, Inc. (DGI) was founded in 2000 and became operational in January 2002.

Inspire Medical Systems

Medisyn Technologies

Crunchbase Website Twitter Facebook Linkedin

Medisyn Technologies develops pre-qualified proprietary drug compounds for breast, renal, prostate, and lung cancer treatments.

Inspire Medical Systems

Exos

Crunchbase Website Twitter Facebook Linkedin

Exos is a medical device company that develops and commercializes thermoformable external musculoskeletal stabilization systems.

Inspire Medical Systems

General Probiotics

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General Probiotics develops innovative cellbots, antimicrobial probiotics that eliminate harmful pathogens in livestock.

Inspire Medical Systems

Kalypto Medical

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Kalypto Medical focuses on expanding the use of Negative Pressure Wound Therapy (NPWT) technology beyond its current reach.

Inspire Medical Systems

Impleo Medical

Crunchbase Website Twitter Facebook Linkedin

Impleo Medical is a developed a proprietary bulking agent therapy for Gastroesophageal Reflux Disease in medical devices

Inspire Medical Systems

Respiratory Sciences

Crunchbase Website Twitter Facebook Linkedin

Respiratory Sciences transforms respiratory care through the expansion of access to care in medical centers and in patient homes.

Inspire Medical Systems

Anatomi

Crunchbase Website Twitter Facebook Linkedin

Anatomi is advancing the fundamental understanding of neurodevelopment and genuine human neural networks.

Inspire Medical Systems

Quench Medical

Crunchbase Website Twitter Facebook Linkedin

Quench Medical is developing a novel aerosol platform technology to deliver medicine into deep areas of the lung.

Inspire Medical Systems

BlueAllele

Crunchbase Website Twitter Facebook Linkedin

BlueAllele is a biotechnology firm that specializes in the development and commercialization of gene editing therapeutics.

Inspire Medical Systems

Children’s Therapy Center

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Children’s Therapy Center specializes in occupational, physical and speech therapy.

Inspire Medical Systems

McFerson Chiropractic

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McFerson Chiropractic provides gentle chiropractic care, soft tissue therapies, and lifestyle coaching services.

Inspire Medical Systems

Denali Medical

Crunchbase Website Twitter Facebook Linkedin

Denali Medical II is a medical device incubator focused on creating new therapies for unmet and/or underserved clinical needs.

Inspire Medical Systems

AneuRx

Crunchbase Website Twitter Facebook Linkedin

AneuRx provides stent-grafts for abdominal aortic aneurysm repair therapy.

Inspire Medical Systems

Acumen Counseling Services

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Acumen Counseling Services provides co-occurring disorder treatment, dialectical behavioral therapy, anxiety, and trauma services.

Inspire Medical Systems

EndoMetabolic Solutions

Crunchbase Website Twitter Facebook Linkedin

EndoMetabolic Solutions develops a medical device for the surgical treatment of obesity.

Inspire Medical Systems

Motion Control Group

Crunchbase Website Twitter Facebook Linkedin

Motion Control Group is a global manufacturer of highly customized motors and motion control solutions for the medical, life sciences.

Inspire Medical Systems

Sleepy Eye Medical Center Hospital

Crunchbase Website Twitter Facebook Linkedin

Sleepy Eye Medical Center Hospital offers healthcare services regarding diabetes, birth, chronic pain, orthopedics and therapy services.

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