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101 Top Minnesota Health Care Companies and Startups of 2021 - Best Startup US

101 Top Minnesota Health Care Companies and Startups of 2021

July 5, 2021
Top Companies (Navigation) show

This article showcases our top picks for the best Minnesota based Health Care companies. These startups and companies are taking a variety of approaches to innovating the Health Care industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Minnesota Health Care Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

Crunchbase Website Twitter Facebook Linkedin

Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Mayo Clinic

Mayo Clinic

Crunchbase Website Twitter Facebook Linkedin

MayoClinic is a nonprofit medical practice and medical research group focused on integrated health care, education, and research.

Mayo Clinic

Bright HealthCare

Crunchbase Website Twitter Facebook Linkedin

Bright HealthCare develops a health insurance service platform designed to deliver a quality healthcare experience.

Mayo Clinic

Miromatrix Medical

Crunchbase Website Twitter Facebook Linkedin

Miromatrix Medical is engaged in the development of fully biological human organs and organ-derived biological products.

Mayo Clinic

CVRx

Crunchbase Website Twitter Facebook Linkedin

CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.

Mayo Clinic

Rae Wellness

Crunchbase Website Twitter Facebook Linkedin

Rae Wellness is a wellness startup that offers a variety of vegan, non-GMO, and gluten-free supplements.

Mayo Clinic

Bind On-Demand Health Insurance

Crunchbase Website Twitter Facebook Linkedin

Bind administers health insurance for self-funded customers. Bind is health insurance rewired for our on-demand world

Mayo Clinic

Gravie

Crunchbase Website Twitter Facebook Linkedin

Gravie specializes in the fields of health insurance, health care, and employer benefits.

Mayo Clinic

Nice Healthcare

Crunchbase Website Twitter Facebook Linkedin

Nice Healthcare brings healthcare services into the patient’s home using a combination of in-person and virtual visits.

Mayo Clinic

Inspire Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

Mayo Clinic

Predictive Oncology

Crunchbase Website Twitter Facebook Linkedin

Predictive Oncology is working with the pharmaceutical, diagnostic, and biotech industries to develop customizable assessment methods.

Mayo Clinic

ABILITY Network

Crunchbase Website Twitter Facebook Linkedin

ABILITY Network offers CMS-approved, secure Medicare and all-payer online access for claims processing and reimbursement.

Mayo Clinic

Zipnosis

Crunchbase Website Twitter Facebook Linkedin

Zipnosis is a hospital and healthcare company that specializes in online diagnosis and triage, telehealth, and virtual care.

Mayo Clinic

HistoSonics

Crunchbase Website Twitter Facebook Linkedin

HistoSonics specializes in developing medical devices, interventional radiology, and surgical robotics.

Mayo Clinic

BetterYou

Crunchbase Website Twitter Facebook Linkedin

BetterYou is a digital wellness platform that helps to make better health and wellness decisions every day.

Mayo Clinic

Vireo Health

Crunchbase Website Twitter Facebook Linkedin

Vireo Health is a physician-led company dedicated to providing patients with best-in-class cannabis-based products and high quality care

Mayo Clinic

Player’s Health

Crunchbase Website Twitter Facebook Linkedin

Player’s Health is an insurance agency that protects athletes and sports organizations with a unique risk management platform.

Mayo Clinic

Monteris Medical

Crunchbase Website Twitter Facebook Linkedin

Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

Mayo Clinic

MIVI Neuroscience

Crunchbase Website Twitter Facebook Linkedin

MIVI Neuroscience focuses on developing and commercializing clinical solutions for neurointerventional procedures.

Mayo Clinic

Relievant Medsystems

Crunchbase Website Twitter Facebook Linkedin

Relievant provides patients with low risk therapy that affords the ability to alleviate their back pain.

Mayo Clinic

Nuvaira

Crunchbase Website Twitter Facebook Linkedin

Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases.

Mayo Clinic

Panbela Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Panbela Therapeutics develops small molecule pharmaceuticals for the oncology and acute care markets.

Mayo Clinic

Calyxt

Crunchbase Website Twitter Facebook Linkedin

Calyxt is an Agbiotech company focused on developing crops with healthier characteristics

Mayo Clinic

Recombinetics

Crunchbase Website Twitter Facebook Linkedin

Recombinetics targets biomedical and regenerative medicine, opening vast new opportunities to improve and extend human life.

Mayo Clinic

Respicardia

Crunchbase Website Twitter Facebook Linkedin

Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

Mayo Clinic

HealthPartners

Crunchbase Website Twitter Facebook Linkedin

HealthPartners is a nonprofit health care provider and health insurance company providing health care services and health plan financing.

Mayo Clinic

ANI Pharmaceuticals

Crunchbase Website Twitter Facebook Linkedin

ANI Pharmaceuticals manufactures oral solid dose products, as well as liquids and topicals.

Mayo Clinic

Datica

Crunchbase Website Twitter Facebook Linkedin

Datica brings the cloud to healthcare and helps highly regulated industries.

Mayo Clinic

Central Logic

Crunchbase Website Twitter Facebook Linkedin

Central Logic is a provider of innovative transfer center and bed management solutions in the healthcare industry.

Mayo Clinic

UnitedHealth Group

Crunchbase Website Twitter Facebook Linkedin

UnitedHealth Group is a healthcare company that offers insurance products and services for everyone.

Mayo Clinic

EnteroMedics

Crunchbase Website Twitter Facebook Linkedin

EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Mayo Clinic

Emerging Therapy Solutions

Crunchbase Website Twitter Facebook Linkedin

Emerging Therapy Solutions is an insurance company that specializes in full management of gene and cell therapy for payers.

Mayo Clinic

NeoChord

Crunchbase Website Twitter Facebook Linkedin

NeoChord is a medical device company that develops devices that allow mitral valve repair to be performed on a beating heart.

Mayo Clinic

NovuHealth

Crunchbase Website Twitter Facebook Linkedin

NovuHealth is the leading healthcare consumer engagement company.

Mayo Clinic

4C Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

4C Medical Technologies is a medical device company that develops minimally invasive therapies for structural heart disease.

Mayo Clinic

Hidrate

Crunchbase Website Twitter Facebook Linkedin

Hidrate is an online community creating a smart water bottle that tracks users’ hydration over time and syncs with their phones.

Mayo Clinic

Ativa Medical

Crunchbase Website Twitter Facebook Linkedin

Ativa Medical is working to make diagnostic test results available in moments, rather than hours and days.

Mayo Clinic

Aria CV

Crunchbase Website Twitter Facebook Linkedin

Aria CV is developing a medical device designed to improve the lives of patients living with the disease of pulmonary hypertension.

Mayo Clinic

Learn to Live

Crunchbase Website Twitter Facebook Linkedin

Learn to Live provides an online CBT-based programs to address psychological problems such as depression, stress, anxiety, and others.

Mayo Clinic

Antares Pharma

Crunchbase Website Twitter Facebook Linkedin

Antares Pharma is a revenue-generating product focused specialty pharmaceutical company

Mayo Clinic

Lifesprk

Crunchbase Website Twitter Facebook Linkedin

Lifesprk is a hospital & health care company that offers home care management and senior living services.

Mayo Clinic

Rebiotix

Crunchbase Website Twitter Facebook Linkedin

Rebiotix is a development-stage biotechnology company focusing on the treatment of GI diseases by developing human microbiome.

Mayo Clinic

NxThera

Crunchbase Website Twitter Facebook Linkedin

NxThera develops medical technologies to treat a variety of endourology conditions, including BPH.

Mayo Clinic

Cardiovascular Systems

Crunchbase Website Twitter Facebook Linkedin

Cardiovascular Systems develops and markets medical devices for the treatment of cardiovascular disease.

Mayo Clinic

Ambient Clinical Analytics

Crunchbase Website Twitter Facebook Linkedin

Ambient Clinical Analytics is a provider of clinical analytics solutions to health systems and hospitals,

Mayo Clinic

Entellus Medical

Crunchbase Website Twitter Facebook Linkedin

Entellus Medical develops technology-based treatment solutions for ENT physicians, their patients and payers.

Mayo Clinic

CHF Solutions

Crunchbase Website Twitter Facebook Linkedin

CHF Solutions is a medical device company that focuses on innovative cardiac assist therapy to treat patients.

Mayo Clinic

Pops Diabetes Care

Crunchbase Website Twitter Facebook Linkedin

Pops Diabetes Care offers a virtual healthcare platform to enable people to self-manage diabetes through consumer-centric sensors.

Mayo Clinic

Omcare

Crunchbase Website Twitter Facebook Linkedin

Omcare is a digital health company that enables remote care and medication adherence.

Mayo Clinic

Joshin

Crunchbase Website Twitter Facebook Linkedin

Joshin offers a disability care app that connects individuals to a network of experienced and screened caregivers.

Mayo Clinic

RedBrick Health

Crunchbase Website Twitter Facebook Linkedin

RedBrick Health, a health engagement and behavior-based technology company, helps organizations optimize their health and wellness programs.

Mayo Clinic

Silk Technologies

Crunchbase Website Twitter Facebook Linkedin

SILKTECH focuses on innovating and developing silk-derived protein (SDP) products for ophthalmic applications

Mayo Clinic

Celcuity

Crunchbase Website Twitter Facebook Linkedin

Celcuity transform care for patients with cancer or autoimmune disease.

Mayo Clinic

Abilitech Medical

Crunchbase Website Twitter Facebook Linkedin

Abilitech Medical is a medical device company providing solutions for patients with neuromuscular conditions.

Mayo Clinic

Minnetronix

Crunchbase Website Twitter Facebook Linkedin

We are a medical technology and innovation company with deep expertise in electronic and electromechanical devices.

Mayo Clinic

Healthsense

Crunchbase Website Twitter Facebook Linkedin

Healthsense is a provider of aging services technology, offering technology-enabled care solutions for the senior care continuum.

Mayo Clinic

Mednet

Crunchbase Website Twitter Facebook Linkedin

Clinical Trial Management Solutions

Mayo Clinic

Netgain Technology

Crunchbase Website Twitter Facebook Linkedin

Netgain’s mission is to improve the patient experience by managing the IT operations of healthcare providers nationwide.

Mayo Clinic

ABS

Crunchbase Website Twitter Facebook Linkedin

ABS designs and develops minimally-invasive technology that focuses on relieving pain in the knee.

Mayo Clinic

OneOme

Crunchbase Website Twitter Facebook Linkedin

OneOme is a collaborative concern between the business builder .

Mayo Clinic

Urotronic

Crunchbase Website Twitter Facebook Linkedin

A Minnesota based, medical device company, making an exciting innovation in urethral stricture treatment.

Mayo Clinic

ShiraTronics

Crunchbase Website Twitter Facebook Linkedin

ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headache.

Mayo Clinic

Tactile Medical

Crunchbase Website Twitter Facebook Linkedin

Tactile Medical develops medical devices that support the treatment of edema and vascular diseases at home.

Mayo Clinic

IMRIS Inc.

Crunchbase Website Twitter Facebook Linkedin

IMRIS provides an image-guided therapy environment, facilitating timely information to clinicians to use during surgical procedures.

Mayo Clinic

Neuroone Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

NeuroOne is a medical technology company focused on improving surgical care for patients suffering from neurological disorders.

Mayo Clinic

Osprey Medical

Crunchbase Website Twitter Facebook Linkedin

Osprey Medical develops and commercializes its propriety CINCOR™ System designed for the prevention of contrast induced mephropathy.

Mayo Clinic

Cardionomic

Crunchbase Website Twitter Facebook Linkedin

Cardionomic is a medical device developer that treats reduced cardiac output.

Mayo Clinic

Apothecary Products

Crunchbase Website Twitter Facebook Linkedin

Apothecary Products has been the Pharmacist’s partner, providing a full line of quality pharmacy supplies and home healthcare products.

Mayo Clinic

GeneMatters

Crunchbase Website Twitter Facebook Linkedin

GeneMatters delivers genetic counseling services for hospitals, health networks, academic research centers, and genetic testing labs.

Mayo Clinic

Branch Basics

Crunchbase Website Twitter Facebook Linkedin

Branch Basics is to revolutionize the health of homes by helping people remove harmful chemicals from their daily lives.

Mayo Clinic

Rotation Medical

Crunchbase Website Twitter Facebook Linkedin

Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.

Mayo Clinic

Spineology

Crunchbase Website Twitter Facebook Linkedin

Spineology provides anatomy-conserving spine surgery technology solutions.

Mayo Clinic

Metavention

Crunchbase Website Twitter Facebook Linkedin

Metavention develops medical devices to help with interventional therapies for Type 2 diabetes.

Mayo Clinic

Sansoro Health

Crunchbase Website Twitter Facebook Linkedin

Sansoro Health is a healthcare information technology company

Mayo Clinic

Torax Medical

Crunchbase Website Twitter Facebook Linkedin

Torax Medical develops an implantable device for the treatment of gastroesophageal reflux disease.

Mayo Clinic

Cogentix Medical

Crunchbase Website Twitter Facebook Linkedin

Cogentix Medical products have increased treatment efficiency and lowered patient risk.

Mayo Clinic

Marani

Crunchbase Website Twitter Facebook Linkedin

Prenatal Care Solutions

Mayo Clinic

Zyga Technology

Crunchbase Website Twitter Facebook Linkedin

Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems.

Mayo Clinic

Imricor Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Imricor Medical Systems develops magnetic resonance imaging compatible electrophysiology tools for the treatment of cardiac arrhythmias.

Mayo Clinic

Venture Med Group

Crunchbase Website Twitter Facebook Linkedin

VMG designs, develops which enable interventionalists to cost effectively treat peripheral artery diseases.

Mayo Clinic

ValenTx

Crunchbase Website Twitter Facebook Linkedin

ValenTx is a development-stage medical device company that focuses on minimally-invasive methods for the treatment of morbid obesity.

Mayo Clinic

Cryosa

Crunchbase Website Twitter Facebook Linkedin

CryOSA is a medical device company developing novel treatments for obstructive sleep apnea.

Mayo Clinic

Treatment.com

Crunchbase Website Twitter Facebook Linkedin

Treatment.com is a healthcare technology startup that uses AI to improve health through personalized recommendations and insights.

Mayo Clinic

SupDoc

Crunchbase Website Twitter Facebook Linkedin

Virtual access to local doctors

Mayo Clinic

Murata Vios

Crunchbase Website Twitter Facebook Linkedin

Murata Vios is a medical technology company developing wireless monitoring platform for intensive healthcare applications.

Mayo Clinic

Luminary Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Luminary Therapeutic is a cancer research center that develops pre-clinical stage cell therapy for cancer and autoimmune diseases.

Mayo Clinic

Mardil Medical

Crunchbase Website Twitter Facebook Linkedin

Mardil Medical is a medical device company developing therapies for structural heart diseases and heart abnormalities.

Mayo Clinic

NightWare

Crunchbase Website Twitter Facebook Linkedin

NightWare is a digital therapeutic platform that helps people suffering from traumatic nightmares to get a more restful night’s sleep.

Mayo Clinic

The Big Know

Crunchbase Website Twitter Facebook Linkedin

The Big Know delivers video courses and podcasts taught by renowned experts.

Mayo Clinic

Interrad Medical

Crunchbase Website Twitter Facebook Linkedin

Interrad Medical develops innovative medical devices for use in minimally invasive interventional and surgical procedures.

Mayo Clinic

Clinician Nexus

Crunchbase Website Twitter Facebook Linkedin

Collaborative Clinical Education Management

Mayo Clinic

MicroOptx

Crunchbase Website Twitter Facebook Linkedin

MicroOptx is an early-stage medical device company that leverages academic bioengineering.

Mayo Clinic

Optum

Crunchbase Website Twitter Facebook Linkedin

OptumInsight provides analytics, technology, and consulting services to improve the performance of health systems.

Mayo Clinic

Sonex Health

Crunchbase Website Twitter Facebook Linkedin

To be the World Leader in ultrasound-guided surgery

Mayo Clinic

Boka

Crunchbase Website Twitter Facebook Linkedin

Modern oral care powered by nature + science.

Mayo Clinic

Prevent Biometrics

Crunchbase Website Twitter Facebook Linkedin

Prevent’s patented technology was developed at Cleveland Clinic by top neurosurgeons

Mayo Clinic

Preceptis Medical

Crunchbase Website Twitter Facebook Linkedin

Preceptis Medical develops surgical tools that allow ear tube procedures to be performed with less pain.

Mayo Clinic

Cardio Flow

Crunchbase Website Twitter Facebook Linkedin

Cardio Flow is an early-stage development company with a new approach to orbital atherectomy.

Mayo Clinic

Elucent Medical

Crunchbase Website Twitter Facebook Linkedin

Elucent Medical is a new idea in breast cancer treatment that exists to bring better healthcare ideas.

Mayo Clinic

Leafline Labs

Crunchbase Website Twitter Facebook Linkedin

LeafLine Labs provides high quality medical cannabis and care to patients.

Mayo Clinic

LogicStream Health

Crunchbase Website Twitter Facebook Linkedin

LogicStream Health provides Hospitals and Health Systems with Strategic Clinical Decision Support Management Solutions.

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