Mark Smith
This article showcases our top picks for the best Michigan based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top Michigan Biotechnology Startups
Data sourced from Crunchbase and SemRush.
Ocuphire Pharma
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Ocuphire Pharma, a clinical-stage biopharmaceutical company, develops and commercializes therapies for patients with ophthalmic disorders.
Strata Oncology
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Strata Oncology is a precision oncology company dedicated to transforming cancer care.
Esperion Therapeutics
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Esperion Therapeutics discovers and develops pharmaceutical products for the treatment of cardiovascular and metabolic diseases.
Swift Biosciences
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Swift Biosciences develops molecular biology reagents for research and diagnostic applications.
Henry Ford Health System
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Henry Ford Health System (HFHS) is one of the nation’s leading comprehensive, integrated health systems.
OPTIMIZERx
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OPTIMIZERx offers consumer and physician platforms and strategies to help patients afford and use their medicines and healthcare products.
Vericel Corp
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Vericel Corp is engaged in the development of treatments for critical cardiovascular diseases.
Millendo Therapeutics
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Millendo Therapeutics is a biopharmaceutical company previously primarily focused on developing novel treatments for endocrine diseases.
ONL Therapeutics
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ONL Therapeutics is a biopharmaceutical company dedicated to protecting vision through the protection of photoreceptors.
Starpharma
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Starpharma Holdings Limited (ASX:SPL, OTCQX:SPHRY) is an ASX 300 company and is a world leader in the development of dendrimer products.
Delphinus Medical Technologies
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Delphinus Medical Technologies develops, commercializes, and services breast cancer screening solutions to hospitals and imaging clinics.
Shoulder Innovations
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Shoulder Innovations has developed a system that exceeds the expectations of the patient, surgeon and hospital administration.
NeuMoDx Molecular
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NeuMoDx Molecular, Inc. operates as a molecular diagnostics company. The company develops solutions for molecular diagnostic (MDx) testing
Cirius Therapeutics
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Cirius Therapeutics is a clinical-stage company that develops insulin sensitizer for the treatment of non-alcoholic steatohepatitis.
Celsee Diagnostics
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Celsee Diagnostics is an innovator of cutting-edge products in the emerging liquid-biopsy field.
Lycera
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Lycera engages in the development of small-molecule immunomodulators for the treatment of patients with autoimmune diseases.
Forever Labs
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Forever Labs banks your stem cells to help you live healthier, longer.
Akadeum Life Sciences
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Akadeum is working to fundamentally change the way that cell sorting is performed and thought about.
Grand River Aseptic Manufacturing
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Grand River Aseptic Manufacturing is a parenteral contract development and manufacturing organization.
Rockwell Medical
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Rockwell Medical is a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD).
Cayman Chemical
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Cayman Chemical is a biotechnology firm that provides assay kits, antibodies, proteins, biochemicals, and contract services.
HYGIEIA
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Hygieia is a developer of a diabetes insulin guidance system used to enhance and simplify insulin therapy.
RetroSense Therapeutics
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RetroSense Therapeutics is a biotechnology company developing gene therapy for vision restoration.
CubeWorks
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CubeWorks is accelerating the future of IoT through millimeter-scale smart sensing solutions.
Ecovia Renewables
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We create high-performing biobased ingredients and materials from sustainable processes at the best value for our customers.
Zivo Bioscience
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ZIVO Bioscience is dedicated to the study, development, and commercialization of naturally derived nutritional compounds.
Stryker
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Stryker is a medical technology company that offers products and services in orthopaedics.
Asalyxa Bio
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Asalyxa Bio is committed to developing neutrophil targeting treatments for diseases with a high unmet medical need.
First Wave Bio
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First Wave Bio develops medical solutions to address the lack of effective and safe treatments for Inflammatory Bowel Disease (IBD).
Armune BioScience
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Armune BioScience develops and commercializes molecular diagnostic and prognostic tests for prostate, lung and breast cancers.
Kraig Biocraft Laboratories
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Kraig Biocraft is a fully reporting biotechnology company, is a developer of genetically engineered spider silk based fiber technologies.
Tetra Therapeutics
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Tetra Therapeutics is a clinical stage biotechnology company developing a portfolio of therapeutic products.
Seraph Biosciences
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Seraph Biosciences is a developer of real-time pathogen detection systems used to treat infections.
LynxDx
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LynxDx offers technologies that enable early cancer detection and improvement of patient care.
AsimicA
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AsimicA focuses on developing novel technologies for improved production in Microbial Biosynthetic Factories.
Metabolic Solutions Development
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Metabolic Solutions Development develops innovative therapeutics based on a novel pharmacological method to treat type two diabetes.
MI Bioresearch
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MI Bioresearch is a contract research organization providing in vivo preclinical imaging services.
Everist Health
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Everist Health is a medicine company developing technologies focused on cancer, cardiovascular diseases and diabetes.
Aquaro Histology
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We provide solutions that improve workflow efficiency, section quality, and consistency in the histology laboratory.
GreenMark Biomedical
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GreenMark is a minimally invasive healthcare company.
Innovative Cardiovascular Solutions
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ICS develops novel solutions that offer full capture and protection from embolic material released during left-sided heart procedures.
Impact Analytical
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Provides testing services for the pharmaceutical, plastics, consumer products and specialty chemical industries.
Tolera Therapeutics
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Tolera Therapeutics is a spin-off of the Cleveland Clinic focused on bringing specific and safer therapies to treat various diseases.
3D Biomatrix
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3D Biomatrix designs and manufactures 3D culture plates and scaffolds for cellular assays in drug discovery operations.
Gemphire Therapeutics
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Gemphire Therapeutics manufactures and markets Gemcabene, an LDL cholesterol-lowering medication.
Tetra Discovery
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Tetra Discovery provides consulting services and research on drug discovery for diseases affecting the central nervous system.
Rubicon Genomics
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Rubicon Genomics was founded in 2000 by two University of Michigan faculty members, Dr. John Langmore and Dr. Vladimir Makarov, who wanted
OncoFusion Therapeutics
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OncoFusion Therapeutics is engaged in the R&D of personalized therapeutics for patients with genetically defined cancers.
Life Magnetics, Inc.
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Life Magnetics is commercializing a graphene based magnetic bead for RNA diagnostics, theraputics, and research.
Endra
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Endra, Inc. provides photoacoustic products and medical imaging technologies in the United States. It offers Nexus 128, a preclinical
Naitive Traits
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Naitive Traits develops native genetic traits that makes corn higher-yielding, resistant to drought, and tolerant of temperature extremes.
Gema
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Gema Diagnostics is a molecular diagnostics company.
Axonia Medical
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Axonia Medical develops technology to rebuild and restore damaged peripheral or central nervous systems from tissue-engineered nerve grafts.
Intrinsic4D
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Intrinsic4D develops 3D medical visualization and image analytic software to improve diagnosis, planning and treatment.
ENT Biotech Solutions
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ENT Biotech Solutions is a venture developing a novel medical device.
BioSavita
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BioSavita’s high throughput synthetic DNA technologies and yeast strains enable the rapid manufacture of fully functional antibodies,
RealBio Technology
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RealBio Technology is focused on developing biorealistic cell and tissue culture technology for research in the field of life science.
BFKW
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BFKW offers Full Sense™ Device, a temporary implantable device that induces long lasting satiety and significant weight loss.
Phrixus Pharmaceuticals
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Phrixus Pharmaceuticals develops and commercializes heart failure-related pharmaceutical products and therapies.
CureLauncher
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CureLauncher is a company focused on enabling users find suitable medical treatments based on their conditions.
TheraB Medical
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TheraB Medical develops a wearable swaddle for the treatment of infant jaundice.
Michigan Endoscopy Center
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Michigan Endoscopy Center is an operator of a non-hospital based outpatient surgery center.
GANTEC
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Gantec is a biotechnology company delivering agriculture solutions.
Medical Engineering Partners
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Medical Engineering Partners is a biomedical device company focused on sensor innovation, miniaturization, engineering, and prototyping.
American BioCare
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American BioCare offers home healthcare services that include skilled nursing, medical residential care, and homemaker and sitter services.
BAMF Health
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BAMF Health is a biotechnology company that designs, develops, and builds cyclotron-equipped radiopharmacies and clinics.
Brighton Biotech
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Brighton Biotech Ltd engages in medical research that focuses on treating a broad range of negative consequences
MMS Holdings Inc.
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MMS is an award-winning, data-focused CRO that supports the pharmaceutical and biotech industries with a proven, scientific approach.
BlueWillow Biologics
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BlueWillow Biologics operates as a clinical-stage privately-held biopharmaceutical company.
NatiMab Therapeutics
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NatiMab Therapeutics identifies and develops human antibodies (Abs) for the therapy and diagnosis of infectious diseases and cancer.
Avomeen Analytical Services
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Avomeen Analytical Services is a chemical testing laboratory that specializes in chemical testing and litigation support services.
Critical Signal Technologies
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Founded in 2006 by security and medical monitoring expert Jeffery S. Prough, Critical Signal Technologies is dedicated to helping our
FreeStride Therapeutics
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FreeStride’s drug restores bone health by preventing both inflammation and bone loss.
BioDiscovery
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BioDiscovery is a scientific software company based in El Segundo, California, focused on genetic research and genomic analysis.
Nymirum
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Nymirum is a venture-backed, privately held company that has developed the RNArchitect suite to rapidly solve high-resolution RNA 3D
Essen BioScience
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Essen BioScience is a world leader in the field of cell-based in vitro assays and instrumentation.
NOTA Labs
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NOTA Labs is a startup company that develops a face mask insert to protect individuals against viral and bacterial pathogens.
Compendia Bioscience
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Compendia Bioscience is dedicated to applying the global collection of cancer genomic data to impact patient treatment by enabling the
BioPro
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BioPro engages the design, manufacture, and distribution of assorted orthopedic implants and surgical devices.
Hibiskus Biopharma
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Hibiskus Biopharma is an early-stage pharmaceutical venture pursuing the development of small-molecule cancer therapy.
HandyLab
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HandyLab is a business that provides the world with research into medical technology.
NxGen MDx
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A women’s health company delivering highly accurate and precise genetic screening results.
Emerald BioAgriculture Corporation
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Emerald BioAgriculture Corporation is a privately held company that develops biochemical products to increase crop production.
Biosciences Research and Commercialization Center (BRCC)
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Biosciences Research and Commercialization Center (BRCC) is a venture capital investment arm of Western Michigan University (WMU).
NeuroNexus Technologies
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NeuroNexus Technologies develops and commercializes neural interface technology, components, and systems for clinical applications.
Epredia
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Epredia is a biotechnology company that provides labeling, tracking, pathology, cancer diagnostics and tissue diagnostics services.
Therapeutic Systems Research Laboratories
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Therapeutic Systems Research Laboratories is a privately-owned preclinical accelerator based in Ann Arbor, Michigan
Phenomics Health
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Phenomics Health is a bioinformatics platform-based precision medicine company.
Sentio
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Sentio, LLC has developed a smart sensor IOM technology for spinal surgery based on MMG.
MTRX
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We harness technology to make our world a healthier and safer place.
Empirical Bioscience
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Empirical Bioscience designs and manufactures molecular biology products for polymerase chain reactions of plants, animals, and human DNA.
iNDIGO Health Partners
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INDIGO Health Partners is a physician-led company committed to sustaining community healthcare.
QuatRx Pharmaceuticals
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QuatRx Pharmaceuticals Company, a biopharmaceutical company, engages in discovering, licensing, developing, and commercializing compounds
Oxford Biomedical Research
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Oxford Biomedical Research manufactures and markets assay kits, recombinant proteins and antibodies for biomedical research.
Accuri Cytometers
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Accuri Cytometers is a medical device company developing cost effective cytometers for laboratories.
DNA Software
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DNA Software provides solutions to DNA diagnostic design and analysis problems.
Genesis Genetics
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Genesis Genetics provides pre-implantation testing of embryos for inherited genetic abnormalities.
Asterand
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Asterand Bioscience is the leading global provider of high quality, well characterized human tissue & human tissue-based research solution.
OcuSciences
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OcuSciences is developing a technique, flavoprotein fluorescence (FPF), and device to detect and monitor retinal metabolic dysfunction.
