101 Best Pennsylvania Venture Capital Companies and Startups

December 31, 2021
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This article showcases our top picks for the best Pennsylvania based Venture Capital companies. These startups and companies are taking a variety of approaches to innovating the Venture Capital industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Pennsylvania Venture Capital Startups

Data sourced from Crunchbase and SemRush.

Alvin Clay Financial Advisors LLC

Alvin Clay Financial Advisors LLC

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Financial Advisor, 401(k), Investment Management, Financial Planning

Main Street Capital Holdings

Main Street Capital Holdings

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Main Street Capital Holdings is private equity firm that makes equity investments.

Main Street Capital Holdings

Valley Green Capital Partners

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Valley Green Capital Partners is an investment banking firm that provides sourcing capital, debt and equity real estate financing services.

Main Street Capital Holdings

Syntiq Ltd

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Syntiq Ltd are changing the way startups find capital by assembling a network of investors and entrepreneurs who can interact directly.

Main Street Capital Holdings

Aberdeen Israel Fund

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The Fund seeks long-term capital appreciation by investing primarily in equity securities of Israeli companies.

Main Street Capital Holdings

Green Swan Partners

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GSP is a dynamic firm that enable businesses through the deployment of transformative digital, technology solutions, and investment capital.

Main Street Capital Holdings

Florida Biomed

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Florida Biomed is a venture capital-backed biotechnology company that specializes in biomedical research.

Main Street Capital Holdings

Aberdeen Indonesia Fund

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The Fund seeks long-term capital appreciation as a primary objective and income as a secondary objective.

Main Street Capital Holdings

CrossMark Funding

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CrossMark funding is a financial management company that assists profitable businesses seeking finance for expansion and capital events.

Main Street Capital Holdings

Innovation Philadelphia

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Innovation Philadelphia offers a range of business consulting and market research services.

Main Street Capital Holdings

MVP Capital Partners

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MVP Capital Partners is an equity firm that invest in several sectors such as pharmaceutical, aviation, manufacturing and healthcare.

Main Street Capital Holdings

Hutchison Whitehead

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Hutchison Whitehead offers wealth and asset management and financial planning solutions.

Main Street Capital Holdings

Rittenhouse Ventures

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Rittenhouse Ventures provides capital & growth strategies with advanced software solutions for healthcare, financial and business services..

Main Street Capital Holdings

BNP Paribas Financial Services

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BNP Paribas Financial Services is a Pennsylvania-based financial service provider.

Main Street Capital Holdings

Hemishare

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Hemishare works with the premier venture capital firms, incubators and accelerators, and startups in Brazil.

Main Street Capital Holdings

Attalus Capital

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Attalus Capital is a asset management firm.

Main Street Capital Holdings

Arch Street Advisors

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Arch Street Advisors is an advisory firm that raises capital for private equity firms and for independent sponsors fund.

Main Street Capital Holdings

The Real Asset Investor

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The Real Asset Investor provides carbon investments, real asset investing, due diligence, and self-storage investment services.

Main Street Capital Holdings

Centra Bank

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Centra Bank is a full-service community bank based in the US.

Main Street Capital Holdings

TigerShares

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TigerShares provides an effective way to access these trends through targeted exposure to leading internet companies in China and the U.S.

Main Street Capital Holdings

EquityStar

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Alternative Investment

Main Street Capital Holdings

MSI Capital Partners

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MSI Capital Partners is an investment management company that finances mid-sized manufacturing and industrial service-related businesses.

Main Street Capital Holdings

County Savings Bank

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County Savings Bank was acquired by BankFirst National.

Main Street Capital Holdings

Nagel & Associates

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Nagel & Associates is a law firm specializing in international commercial transactions, asset protection, and estate planning.

Main Street Capital Holdings

Cloudshadow

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Cloudshadow is a next-generation consultancy and venture resources firm.

Main Street Capital Holdings

InVizion

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InVizion creates systems integration communication tools for designing and comparing project scenarios, as well as measuring the effects.

Main Street Capital Holdings

Media Capital Advisors

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Media Capital Advisors is serving companies in Media and Communications.

Main Street Capital Holdings

Rotay Capital Finance

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Rotay Capital Finance acts as a funding resource & provides business financial services to the traditional banking & credit union sectors.

Main Street Capital Holdings

Matrix Venture Capital Management

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Matrix Venture Capital Management is a venture investment management company that offers financial services.

Main Street Capital Holdings

The Greater Philadelphia Venture Group

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The GPVG’s mission is to cultivate a vibrant private equity and entrepreneurial community by providing compelling programming.

Main Street Capital Holdings

Health Start Partners

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Strategy and Management Consulting & Capital Development

Main Street Capital Holdings

Incomestore

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Income Store provides individuals, companies and private equity firms with new income streams.

Main Street Capital Holdings

Solebury Capital

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Solebury Capita is a financing advisory and brokerage firm.

Main Street Capital Holdings

First Northern Bank & Trust Co

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First Northern Bank & Trust Co is a bank that offers commercial and consumer lending services.

Main Street Capital Holdings

Capography

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Capography is a website where users can buy and sell wearable art such as stickers and patches.

Main Street Capital Holdings

ELB Capital Management

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ELB Capital Management is a financial service-based company.

Main Street Capital Holdings

Align5

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Align5 is an advisory firm that provides investment, strategic planning and coaching services to promote market growth for organizations,

Main Street Capital Holdings

Falls Bridge Capital

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Falls Bridge Capital is a capital-raising advisory firm that provides alternative asset fundraising services for investors.

Main Street Capital Holdings

FNCB

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FNCB is a banking firm providing savings, checking, mortgage loan and banking services.

Main Street Capital Holdings

Pennstar Bank

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Pennstar Bank is a bank that serves in northeastern Pennsylvania.

Main Street Capital Holdings

American Dream Mortgage

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American Dream Mortgage is a financial services company offering direct mortgage lending services.

Main Street Capital Holdings

GreenWorld Capital

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GreenWorld Capital provides raising capital, investment banking, mergers, acquisitions, financial, and strategic services.

Main Street Capital Holdings

American Home Bank

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American Home Bank is a banking corporation headquartered in Pennsylvania.

Main Street Capital Holdings

Allegheny Valley Bank

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Allegheny Valley Bank is a Pennsylvania-based full-service community bank.

Main Street Capital Holdings

Diamond Equity Partners

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Diamond Equity Partners is into opportunity value investments in firms with a strong management team, brand equity and good market position.

Main Street Capital Holdings

American Heritage Federal Credit Union

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American Heritage Federal Credit Union is a banking firm that offers community banking services in the Philadelphia.

Main Street Capital Holdings

American Seeds

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A new holding company that will support regional seed businesses with capital, genetics and technology investments

Main Street Capital Holdings

Aberdeen Chile Fund

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The Fund seeks total return, consisting of capital appreciation and income, by investing primarily in Chilean securities.

Main Street Capital Holdings

Huntingdon Valley Bank

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Huntingdon Valley Bank has offices located across Philadelphia.

Main Street Capital Holdings

Luttner Financial Group

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Luttner Financial Group is a Pennsylvania-based wealth management firm.

Main Street Capital Holdings

BCI Technology Investments

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BCI Technology Investments renders venture capital, private equity, funding, renewable energy hardware, and logistics services.

Main Street Capital Holdings

GF Data

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GF Data provides valuation data on private-equity sponsored middle-market transactions and capital ventures.

Main Street Capital Holdings

Pacer Financial

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Pacer Financial is a financial services company that provides financial advisory and distribution services.

Main Street Capital Holdings

Apex Mortgage Corp.

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Apex Mortgage Corp. is a banking firm that deals in commercial mortgages, commercial real estate mortgages, refinancing, and funding.

Main Street Capital Holdings

Byler Holdings

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Byler Holdings invests in real estate, golf management, entertainment, material group companies besides operates those firms & properties.

Main Street Capital Holdings

The Lomax Companies

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The Lomax Companies is a private investment firm that focuses on venture capital and real estate investing.

Main Street Capital Holdings

AmeriServ Financial Bank

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AmeriServ Financial Bank is a banking firm based in Pennsylvania.

Main Street Capital Holdings

Creative Financial Group

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Creative Financial Group is a business financial services group based in Pennsylvania.

Main Street Capital Holdings

Berwind Financial Group

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Berwind Financial Group is an equity investor and investment banking firm serving middle market companies.

Main Street Capital Holdings

Eureka Equity Partners

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Eureka Equity Partners is an investment firm that specializes in venture capital and private equity investments.

Main Street Capital Holdings

Hatch Biofund Management

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Hatch Biofund Management provides venture capital services for life science and biotechnology.

Main Street Capital Holdings

Peachtree Financial Solutions

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Peachtree Financial Solutions is a Pennsylvania-based financial services firm.

Main Street Capital Holdings

The Haverford Trust Company

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The Haverford Trust Company is an investment banking company that offers wealth advisory and investment management services.

Main Street Capital Holdings

Marion Street Capital

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Management consulting firm working with early-stage growth companies to help solve their most pressing challenges.

Main Street Capital Holdings

Venturef0rth

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Venturef0rth provides tech startups and early-stage companies a physical home in Philadelphia designed for coworking.

Main Street Capital Holdings

PeoplesBank, A Codorus Valley Company

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PeoplesBank is a bank provides personal banking, mortgage banking, and wealth management services.

Main Street Capital Holdings

Rockwell Venture Capital

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RVC has provided funding as well as management oversight to a variety of technologists with a keen understanding of business opportunities.

Main Street Capital Holdings

Lifetime Financial Growth

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Lifetime Financial Growth is a financial services firm based in Pennsylvania, Ohio, Kentucky, and West Virginia.

Main Street Capital Holdings

Mars National Bank

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Mars National Bank is a bank that provides retail banking and wealth management services.

Main Street Capital Holdings

Arca Group Inc

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Arca Group Inc is a venture capital firm engaged in publishing and consulting.

Main Street Capital Holdings

NexTier Bank

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NexTier Bank is a bank that offers community banking services.

Main Street Capital Holdings

Fidelity Deposit and Discount Bank

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Fidelity Deposit and Discount Bank is a community bank with offices across Lackawanna and Luzerne Counties.

Main Street Capital Holdings

Singh Ventures

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Singh Ventures is a Philadelphia-based venture capital firm investing in early-stage technology companies, and develops their brand.

Main Street Capital Holdings

Context Capital Partners

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A seeding firm focused on alternative investment strategies .

Main Street Capital Holdings

JM Search

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JM Search is a premier retained executive search firm that delivers high performance leaders and transformational leadership teams.

Main Street Capital Holdings

LawCoin

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LawCoin is a litigation finance and digital assets company.

Main Street Capital Holdings

Fox Chase Bank

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Fox Chase Bancorp, Inc. is a holding company for Fox Chase Bank (the Bank).

Main Street Capital Holdings

Greater Philadelphia Alliance for Capital and Technologies (PACT)

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The Greater Philadelphia Alliance for Capital and Technologies (PACT) connects investors, entrepreneurs and professional advisors.

Main Street Capital Holdings

Mdm Equity Partners

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Mdm Equity Partners, an investment company, provides entrepreneurs with capital and business support to help them grow their companies.

Main Street Capital Holdings

Marks Baughan Securities

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Provides investment banking services to growth companies.

Main Street Capital Holdings

Coastal Credit LLC

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Coastal Credit LLC is a financial services firm based in Indiana.

Main Street Capital Holdings

Emerald Park Capital

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Emerald Park Capital provides debt and equity for emerging growth companies.

Main Street Capital Holdings

Carnegie Foundry

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Carnegie Foundry is an autonomous robotics and AI company manufacturing and developing mission-critical vehicles and essential equipment.

Main Street Capital Holdings

AJO

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AJO is an investment management company that provides investment management and quantitative investing services.

Main Street Capital Holdings

Closed Loop Capital

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Closed Loop Capital is an early-stage venture capital platform investing in exceptional agricultural entrepreneurs.

Main Street Capital Holdings

SEI

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SEI provides asset management, investment processing, and investment operation solutions.

Main Street Capital Holdings

Dollar Bank

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Dollar Bank is a full service, regional bank providing banking services

Main Street Capital Holdings

Archetype Solutions Group

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Archetype Solutions Group grows extraordinary businesses by operationalizing innovation.

Main Street Capital Holdings

Best Money Decisions

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Best Money Decisions LLC was founded by Bruce Scott DeHaven, Sr. in 1995.

Main Street Capital Holdings

Adams Capital Management

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Adams Capital Management, Inc. (ACM) is a national venture capital firm specializing in early-stage applied technology investments.

Main Street Capital Holdings

Brandywine Global Investment Management

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Brandywine Global Investment Management is an investment management company that provides investment and asset performance solutions.

Main Street Capital Holdings

Brainchild Holdings

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Kal Vepuri’s personal investment vehicle.

Main Street Capital Holdings

Karlani Capital

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Karlani Capital is an operating fund that builds, buys, and invests in fast-growing, technology companies that serve and enrich humanity.

Main Street Capital Holdings

Juno Capital

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Juno Capital is an early-stage venture capital firm.

Main Street Capital Holdings

Private Venture

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High Risk High Returns

Main Street Capital Holdings

1315 Capital

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1315 Capital provides expansion and growth capital to commercial stage pharmaceuticals, medical technologies, and healthcare services.

Main Street Capital Holdings

NewSpring

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NewSpring Capital is focused on leveraging operational expertise and capital to build market leading companies.

Main Street Capital Holdings

Dorm Room Fund

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Dorm Room Fund is the strongest community of entrepreneurial students in the nation.

Main Street Capital Holdings

Safeguard Scientifics

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Safeguard Scientifics provides capital and operational support to growth-stage health care and technology companies.

Main Street Capital Holdings

Susquehanna International Group (SIG)

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SIG is a global quantitative trading firm committing its own capital to trade financial products around the world.

Main Street Capital Holdings

Osage Venture Partners

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Osage Venture Partners is a venture capital fund specializing in early stage, B2B software companies on the East Coast.

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