101 Best Ohio Non Profit Companies and Startups

September 7, 2021
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This article showcases our top picks for the best Ohio based Non Profit companies. These startups and companies are taking a variety of approaches to innovating the Non Profit industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Ohio Non Profit Startups

Data sourced from Crunchbase and SemRush.

Cleveland Clinic

Cleveland Clinic

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Cleveland Clinic is a non-profit medical center that combines clinical and hospital care with research and education.

Big Lots

Big Lots

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Big Lots is a discount retailer that offers affordable solutions in the merchandise categories such as furniture, food, decor, and more.

Big Lots

Initiate Studios

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Initiate Studios is a creative programming and design outreach start-up studio.

Big Lots

FrontLine Service

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FrontLine Service is a private non-profit community.

Big Lots

The Dayton Foundation

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The Dayton Foundation, a community foundation, supports users to help people in the Greater Dayton region.

Big Lots

PlayhouseSquare

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PlayhouseSquare is a performing arts center.

Big Lots

The Cleveland Foundation

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The Cleveland Foundation is a community foundation in the U.S.

Big Lots

Dayton RTA

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The Greater Dayton RTA is the public transit agency that citizens count on in Montgomery County and western Greene County.

Big Lots

Lake Health

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Lake Health is a private, not-for-profit leader in community health care.

Big Lots

VeloSano

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VeloSano is more than a fundraising event. It’s more than simply a bike ride

Big Lots

Kids Read Now

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Kids Read Now is a non-profit organization designed to eliminate the summer reading slide for hundreds of schools from coast to coast.

Big Lots

The Greater Cincinnati Foundation

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The Greater Cincinnati Foundation helps people make the most of their giving to build a better community.

Big Lots

Big River

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Big River helps nonprofit organizations raise money by engaging donors through cloud-based targeting, promotions and social marketing.

Big Lots

CareSource

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CareSource is a leading non-profit public sector managed care company

Big Lots

Lake Erie Energy Development Corp

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Lake Erie Energy Development Corp is a financial development agency that provides wind energy, community outreach.

Big Lots

Akron Community Foundation

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They embrace and enhance the work of charitable people who make a permanent commitment to the good of the community.

Big Lots

Youngstown State University Foundation

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Youngstown State University Foundation is an independent, non-profit organization

Big Lots

Mercy Health

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Mercy Health is a mission-driven, integrated healthcare organization.

Big Lots

BRITE Energy Innovators

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BRITE empowers founders to launch energy technology solutions through entrepreneurial guidance and support services.

Big Lots

HCDC

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Hamilton County Business Center is a business incubation program helping entrepreneurs in Greater Cincinnati build successful companies.

Big Lots

Sisters of Charity Foundation of Cleveland

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The foundation works to end homelessness in Cuyahoga County and to reduce health and education disparities .

Big Lots

Mahoning Valley Economic Development Corporation

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Mahoning Valley Economic Development Corporation is a non-profit economic development corporation.

Big Lots

Saint Luke’s Foundation

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Saint Luke’s Foundation is dedicated to improving and transforming the health and well-being of individuals, families and communities.

Big Lots

Eastgate Regional Council of Governments

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Eastgate Regional Council of Governments is a voluntary association of local governments.

Big Lots

Central Clinic Behavioral Health

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Central Clinic Behavioral Health provides mental health services.

Big Lots

GiveNext

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GiveNext is an online platform that enables donors and non-profits to track and manage their charitable contributions.

Big Lots

SunDown RunDown Group

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SunDown RunDown hosts monthly business pitch events for entrepreneurs, classes, workshops, mentors, and access to capital

Big Lots

Donor Drive

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Donor Drive is the fundraising platform for enterprise nonprofits to create better fundraising experiences.

Big Lots

Dynamic Catholic

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Dynamic Catholic offers spiritual development resources, evangelization resources, and Video-based email programs.

Big Lots

TQL

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TQL is one of the largest 3PLs in North America. They arrange the movement of more than 20,000 loads of freight per week.

Big Lots

Nightlight Cinema

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Nightlight Cinema is an independent, nonprofit movie theater. Advancing cinema and community in tandem.

Big Lots

Walnut Hills Redevelopment Foundation

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Walnut Hills Redevelopment Foundation is a a non-profit community development corporation .

Big Lots

Interfaith Hospitality Network

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Interfaith Hospitality Network is a non profit organisation that provides homeless families emergency shelter and hospitality.

Big Lots

Lutheran Social Services

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Lutheran Social Services is a (LSS) helps thousands of people in need throughout 27 Ohio counties.

Big Lots

Mission Essential Personnel

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Mission Essential is a global services and solutions provider to the defense and intelligence communities.

Big Lots

Lydia’s House

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Lydia’s House provides housing for women and their young children.

Big Lots

Wright-Patt Credit Union

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Wright-Patt Credit Union is a not-for-profit member-owned financial institution.

Big Lots

Ingage Partners, LLC

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Ingage Partners was founded to Inspire and Engage people to blend their professional lives with their desire to better our communities.

Big Lots

Genesis HealthCare System

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Genesis HealthCare System operates with a mission to provide quality healthcare for cancer, heart and vascular, surgical and orthopedics.

Big Lots

Clearview Federal Credit Union

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Clearview Federal Credit Union is a non-profit financial service company that offers loans, credit cards, mortgages and banking solutions.

Big Lots

STRS Ohio

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STRS Ohio is one of the nation’s premier retirement systems, serving nearly a half million active and retired Ohio public educators.

Big Lots

Pro Football Hall of Fame

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Honor the Heroes of the Game, Preserve its History, Promote its Values & Celebrate Excellence EVERYWHERE.

Big Lots

Corporate One

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Corporate One provides cash management, liquidity, investments and digital payment solutions to credit unions.

Big Lots

Battelle for Kids

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Battelle for Kids is a non-profit organization helps teachers and leaders to improve school systems.

Big Lots

Unify Labs

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Unify Labs is a nonprofit tech innovation center that transforms the hiring experience fo job seekers and employers.

Big Lots

Collective Health

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Collective Health is to improved upstream health factors that drive more than half of downstream illness and costs.

Big Lots

Equitas Health

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Equitas Health specializes in LGBTQ healthcare, advocacy, dentistry, transgender care, pharmacy, wellness and HIV/STI prevention services.

Big Lots

Day Air Credit Union

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Day Air Credit Union is a nonprofit organization that offers financial services.

Big Lots

Fidelity Charitable

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Since 1991, Fidelity Charitable has helped donors support over 190,000 nonprofit organizations with more than $19 billion in grants.

Big Lots

General Electric Credit Union

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General Electric Credit Union offers investment, real estate, legal, financial, identity theft and debt management services.

Big Lots

Drund

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Drund is a private communications platform enabling nonprofits, education institutions and families to safely share information.

Big Lots

The Rock and Roll Hall of Fame and Museum

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Is the nonprofit organization that exists to educate visitors, fans and scholars from around the world.

Big Lots

Wilson Health

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Wilson Health is a healthcare system and hospital that renders comprehensive health care services to patients.

Big Lots

Federation of State Boards of Physical Therapy

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Federation of State Boards of Physical Therapy focuses on providing services that help incompetent physical therapy practice.

Big Lots

Recovery Resources

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Recovery Resources is a nonprofit organization that provides behavioral health and addiction services.

Big Lots

Jani-King of New Orleans

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Jani-King is one of the world’s most inspiring companies and truly represents entrepreneurial spirit.

Big Lots

Safecare

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Safecare is a web-based screening service that monitors nurses’ aides and reports any act of abuse or criminal activities.

Big Lots

OKI Regional Council of Governments

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OKI Regional Council of Governments is a panel with a common objective of developing unified strategies to improve the quality of life.

Big Lots

Sun Federal Credit Union

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Sun Federal Credit Union is a full-service financial firm that serves sponsor groups and designated communities.

Big Lots

Wood County Hospital

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Wood County Hospital is a not-for-profit hospital that is dedicated to comprehensive healthcare and emergency services.

Big Lots

NorTech

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NorTech is a technology-focused organization.

Big Lots

Ohio University Credit Union

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Ohio University Credit Union is a not-for-profit financial cooperative focused on improving the financial well being of members.

Big Lots

Wayne HealthCare

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Wayne HealthCare is a non-profit hospital that delivers complete healthcare and emergency services.

Big Lots

Greater Cincinnati Behavioral Health Services

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Greater Cincinnati Behavioral Health Services is a mental health services agency.

Big Lots

Cuyahoga County Public Library

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Cuyahoga County Public Library provides knowledge online with a digital collection of books and mobile printing as well as photo services.

Big Lots

Wingspan Care Group

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Wingspan Care Group is a non-profit administrative and management organization that provides a united community-based network of services.

Big Lots

Ohio Hospital Association

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Ohio Hospital Association engaged in the collaboration with member hospital and health systems to enhance the well being of the residents.

Big Lots

National Business Incubation Association

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National Business Incubation Association

Big Lots

OPC Foundation

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The OPC Foundation is dedicated to ensuring interoperability in automation.

Big Lots

Fairfield Medical Center

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FMC is a hospital & healthcare specializes in provides efficient, high quality healthcare for patients and their families.

Big Lots

Ohio’s Hospice

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Ohio’s Hospice is an NGO that renders superior care, hospitality, medical, patient and healthcare services for communities.

Big Lots

Koinonia Homes

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Koinonia Homes is a non-profit organization that provides services for people with intellectual and developmental disabilities.

Big Lots

COSI

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Center of Science and Industry in Columbus, OH

Big Lots

Ohio Catholic Federal Credit Union

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Ohio Catholic Federal Credit Union is a nonprofit financial services provider company.

Big Lots

Education First Credit Union

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Education First Credit Union serves the education community.

Big Lots

Team NEO

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Team NEO is an economic development organization focused on creating jobs

Big Lots

Otterbein

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Otterbein specializes in offering a wide range of assisted living, rehabilitation, nursing care and home health care services.

Big Lots

Women’s Small Business Accelerator

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Women’s Small Business Accelerator was formed to help all women business owners.

Big Lots

Jeffrey Thomas Hayden Foundation

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The Jeffrey Thomas Hayden Foundation is a registered 501(c)3 non-profit organization founded in September 2004.

Big Lots

Columbus Partnership

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The Columbus Partnership is a non-profit, membership-based CEO organization.

Big Lots

Clovernook

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Clovernook is a non-profit organization that empowers people who are blind and visually impaired to be self-sufficient in their communities.

Big Lots

Education at Work

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Education at Work is an outsourcing company that helps college students to secure their finances by rendering job opportunities.

Big Lots

The Columbus Association For The Performing Arts

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CAPA is a non-profit, award-winning performing arts organization, presenting national and international performing arts and entertainment.

Big Lots

Lima Memorial Health System

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Lima Memorial Health System offers primary care, pediatric, telehealth, women’s health, neonatal, home healthcare & rehabilitation services.

Big Lots

Genfed Financial Credit Union

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Genfed Financial Credit Union offers savings, loans, credit cards, mortgages, online banking and financial servcies.

Big Lots

Dayton Development Coalition

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Dayton Development Coalition is the regional economic development and advocacy organization.

Big Lots

Ohio Capital Corporation for Housing

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Ohio Capital Corporation for Housing is a non-profit organization that provides economic growth and affordable housing opportunities.

Big Lots

Health Recovery Services

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Health Recovery Services is a drug addiction treatment center that provides education, prevention, treatment and other supportive services.

Big Lots

Ohio Farm Bureau Federation

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The Ohio Farm Bureau Federation is a social organization that focuses on supporting agriculture and states food and farm communities.

Big Lots

Apprisen

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Apprisen is a platform that specializes in offering a wide range of services to its clients to achieve their financial health and wealth.

Big Lots

Greater Cleveland Food Bank

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Greater Cleveland Food Bank works with individuals and food manufacturers to distribute free food to schools, daycares & emergency shelters.

Big Lots

Summit Academy Management

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Summit Academy Schools, a network of K-12 tuition-free, non-profit public schools that compassionately serve students who learn differently.

Big Lots

Ohio Environmental Protection Agency

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Ohio Environmental Protection Agency protects the environment and public health.

Big Lots

Uct Property Inc.

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UCT is a non-profit financial services membership organization based in Columbus, Ohio.

Big Lots

TCN Behavioral Health Services

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TCN Behavioral Health Services is a mental health care center that expertise in behavioral health, psychiatry and prevention services.

Big Lots

The American Society for Nondestructive Testing

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The American Society for Nondestructive Testing is the technical society for nondestructive testing professionals.

Big Lots

The Center for Health Affairs

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The Center for Health Affairs is a nonprofit organization that helps in the healthcare industry.

Big Lots

Cornucopia, Inc.

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Cornucopia is a nonprofit organization that helps people with disabilities develop skills and confidence leading to sustainable employment.

Big Lots

The Ohio Masonic Home

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The Ohio Masonic Home provides family and community resources such as nursing care, assisted living, rehabilitation and therapy.

Big Lots

Emery Federal Credit Union

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Emery Federal Credit Union is a not-for-profit financial cooperative.

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