101 Best North Carolina Medical Device Companies and Startups

February 7, 2023
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This article showcases our top picks for the best North Carolina based Medical Device companies. These startups and companies are taking a variety of approaches to innovating the Medical Device industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top North Carolina Medical Device Startups

Data sourced from Crunchbase and SemRush.

Validic

Validic

Crunchbase Website Twitter Facebook Linkedin

Validic is a technology platform that offers digital health and remote care programs for healthcare organizations.

Bioventus

Bioventus

Crunchbase Website Twitter Facebook Linkedin

Bioventus delivers clinically proven, cost-effective products that help people heal quickly and safely.

Bioventus

Asensus Surgical

Crunchbase Website Twitter Facebook Linkedin

Advancing laparoscopic surgery through innovation – Senhance™ Surgical Robotic System by Asensus Surgical

Bioventus

Asklepios BioPharmaceutical

Crunchbase Website Twitter Facebook Linkedin

Asklepios BioPharmaceutical is a biotechnology company developing adeno-associated virus (AAV) gene therapies for genetic disorders.

Bioventus

Restor3d

Crunchbase Website Twitter Facebook Linkedin

Restor3d offers surgeons with biomaterials, 3D printing technologies, and artificial intelligence to repair and rebuild the human body.

Bioventus

HZO

Crunchbase Website Twitter Facebook Linkedin

HZO delivers customized protective nano and conformal coatings that safeguard electronics from the most demanding environments.

Bioventus

Baebies

Crunchbase Website Twitter Facebook Linkedin

Baebies develops early disease detection and comprehensive diagnostic solutions.

Bioventus

Spencer Health Solutions

Crunchbase Website Twitter Facebook Linkedin

Spencer Health Solutions is a transforming healthcare by moving care delivery to the home.

Bioventus

Monarch Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

Monarch Medical Technologies is a provider of precision insulin dosing technology to help improve glycemic control outcomes.

Bioventus

410 Medical

Crunchbase Website Twitter Facebook Linkedin

410 Medical is a medical device company dedicated to developing innovative products that enable frontline medical providers to improve care.

Bioventus

Arrivo BioVentures LLC

Crunchbase Website Twitter Facebook Linkedin

Arrivo BioVentures is a pharmaceutical development company which focuses on identifying biologics and molecules to improve patient care.

Bioventus

Micell Technologies

Crunchbase Website Twitter Facebook Linkedin

Micell Technologies is a biomedical device company developing interventional cardiology systems for vascular drug delivery.

Bioventus

Cone Health

Crunchbase Website Twitter Facebook Linkedin

Cone Health is a not-for-profit network of health care providers serving people in Guilford, Forsyth, Rockingham and surrounding counties.

Bioventus

Lumedica

Crunchbase Website Twitter Facebook Linkedin

Lumedica is a technology startup that makes low-cost, high-performance imaging technologies to improve disease detection across the world.

Bioventus

NuPulseCV

Crunchbase Website Twitter Facebook Linkedin

NuPulse specializes in developing technology designed to treat patients with heart failure.

Bioventus

VitalFlo

Crunchbase Website Twitter Facebook Linkedin

VitalFlo provides preventative respiratory health insights when patients need it most: before they have an asthma attack.

Bioventus

KNOW Bio

Crunchbase Website Twitter Facebook Linkedin

KNOW Bio, LLC develops and produces nitric oxide-based therapies.

Bioventus

BioMarck Pharmaceuticals

Crunchbase Website Twitter Facebook Linkedin

BioMarck Pharmaceuticals develops new drugs for the treatment of pulmonary diseases.

Bioventus

TearScience

Crunchbase Website Twitter Facebook Linkedin

TearScience develops devices that provide significant clinical identification and treatment of evaporative dry eye.

Bioventus

Surround Medical System

Crunchbase Website Twitter Facebook Linkedin

Surround Medical System develops 3D X-ray imaging medical devices featuring a carbon nanotube (CNT) X-ray source.

Bioventus

Aires Medical

Crunchbase Website Twitter Facebook Linkedin

Aires Medical is a medical device company that makes oxygen and ventilation devices for COPD patients.

Bioventus

HyperBranch Medical Technology

Crunchbase Website Twitter Facebook Linkedin

HyperBranch Medical Technology develops and commercializes products for the traumatic or surgically-induced wound market.

Bioventus

Humacyte

Crunchbase Website Twitter Facebook Linkedin

Humacyte develops products for vascular diseases and replacement of anatomical conduits.

Bioventus

Gilero

Crunchbase Website Twitter Facebook Linkedin

Gilero specializes in designing and manufacturing devices for the medical and pharmaceutical industries.

Bioventus

Alievio

Crunchbase Website Twitter Facebook Linkedin

Alievio is a North Carolina-based innovative glaucoma medical device company.

Bioventus

Levee Medical

Crunchbase Website Twitter Facebook Linkedin

Levee Medical develops and manufactures urological devices with the focus of improving recovery outcomes for radical prostatectomy patients.

Bioventus

SonoVascular

Crunchbase Website Twitter Facebook Linkedin

SonoVascular develops a multi-mechanistic thrombectomy system for the treatment of arterial and venous diseases.

Bioventus

InnAVasc Medical

Crunchbase Website Twitter Facebook Linkedin

InnAVasc Medical is a medical device company that designs and develops products for vascular access for hemodialysis.

Bioventus

Perfusio

Crunchbase Website Twitter Facebook Linkedin

Perfuiso markets an FDA cleared non-invasive surgical imaging device.

Bioventus

Grid Therapeutics

Crunchbase Website Twitter Facebook Linkedin

Grid develops an innovative platform to develop human derived antibodies focusing on cancer therapeutics.

Bioventus

Polarean

Crunchbase Website Twitter Facebook Linkedin

Polarean is manufacturer and service provider for noble gas polarizer devices and ancillary instruments.

Bioventus

Meryx

Crunchbase Website Twitter Facebook Linkedin

Meryx is a biotechnology company that develops orally bio-available cancer drugs targeting receptor tyrosine kinases.

Bioventus

Ramona Optics

Crunchbase Website Twitter Facebook Linkedin

Ramona Optics offers computational microscope capable of large field-of-view and high-resolution imaging.

Bioventus

Tryton Medical

Crunchbase Website Twitter Facebook Linkedin

Tryton Medical manufactures and sells stent systems for the treatment of bifurcation lesions.

Bioventus

Contego Medical

Crunchbase Website Twitter Facebook Linkedin

Contego Medical develops a family of novel embolic protection devices.

Bioventus

Cellective BioTherapy

Crunchbase Website Twitter Facebook Linkedin

Cellective BioTherapy develops novel cellular and monoclonal antibody-based platforms to treat cancer, autoimmunity, and immunodeficiency.

Bioventus

Raleigh Radiology

Crunchbase Website Twitter Facebook Linkedin

Raleigh Radiology is a hospital and health care company that offers medical imaging services.

Bioventus

URO-1

Crunchbase Website Twitter Facebook Linkedin

URO1 is an early stage medical products developer for urology procedures.

Bioventus

CoLucid Pharmaceuticals

Crunchbase Website Twitter Facebook Linkedin

CoLucid Pharmaceuticals is a biotechnology company focusing on therapies for central nervous system disorders.

Bioventus

Veranex

Crunchbase Website Twitter Facebook Linkedin

Veranex is an end-to-end, global, tech-enabled, concept-through-commercialization service provider focuses on medical technology.

Bioventus

C³HealthcareRx

Crunchbase Website Twitter Facebook Linkedin

It is a Raleigh based health care company.

Bioventus

Diamond Orthopedic

Crunchbase Website Twitter Facebook Linkedin

Diamond Orthopedic is an exclusive provider of faceted threadform technology for orthopedic applications worldwide.

Bioventus

Cutting Edge Spine

Crunchbase Website Twitter Facebook Linkedin

Cutting Edge Spine is a medical device company that develops and distributes new generation spinal technologies.

Bioventus

React Innovations

Crunchbase Website Twitter Facebook Linkedin

React Innovations manufactures non-invasive neuromuscular therapy devices that use in atrophy prevention and pain management.

Bioventus

Diabetic Health

Crunchbase Website Twitter Facebook Linkedin

Diabetic Health is a startup based in Research Triangle Park.

Bioventus

AURA Technologies

Crunchbase Website Twitter Facebook Linkedin

AURA Technologies is a defense and Intelligence Technology Company.

Bioventus

Gradient Medical

Crunchbase Website Twitter Facebook Linkedin

Gradient Medical develops novel interventional oncology services to bring ACE therapy to the clinic.

Bioventus

Amissa

Crunchbase Website Twitter Facebook Linkedin

Amissa’s predictive analytics platform helps improve Alzheimer’s caregiving and recommends modified behaviors to delay the onset of disease.

Bioventus

Reselute

Crunchbase Website Twitter Facebook Linkedin

Reselute develops solutions for the treatment of orthopaedic implant related infections.

Bioventus

Ideal Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

Ideal Medical Technologies focuses on improving healthcare through technological innovation.

Bioventus

Islet Sciences

Crunchbase Website Twitter Facebook Linkedin

Islet Sciences develops a vialed suspension of micro-encapsulated porcine islets for injection into the abdominal cavity.

Bioventus

Translational Imaging Innovations

Crunchbase Website Twitter Facebook Linkedin

TII is developing software platforms that integrate imaging science workflows to shorten the timeline of ocular innovations.

Bioventus

XinVivo

Crunchbase Website Twitter Facebook Linkedin

XinVivo is a naotech firm focused on medical devices and 3D scanning technology.

Bioventus

BTI Targetry

Crunchbase Website Twitter Facebook Linkedin

BTI Targetry specializes in the development and deployment of high-performance targets for radionuclide production.

Bioventus

Carolina Lithotripsy

Crunchbase Website Twitter Facebook Linkedin

Carolina Lithotripsy is a healthcare company that provides lithotripsy services.

Bioventus

Phoenix Cardiac

Crunchbase Website Twitter Facebook Linkedin

Phoenix Cardiac, Inc. is to design, develop, and market new and innovative patented technologies in the cardiac medical device field.

Bioventus

HOLLO medical

Crunchbase Website Twitter Facebook Linkedin

HOLLO is a building product for inhaler-users who are frustrated with cumbersome valved holding chambers.

Bioventus

BiomedInnovations

Crunchbase Website Twitter Facebook Linkedin

BiomedInnovations are developing technologies for long-term storage and interaction with large tissues and organs outside of the human body.

Bioventus

NeuroVice

Crunchbase Website Twitter Facebook Linkedin

NeuroVice is an innovative company developing a new, disruptive medical device technology that improves the patient experience.

Bioventus

AthemBio

Crunchbase Website Twitter Facebook Linkedin

AthemBio develops breakthrough technologies and transform them into solutions to solve major bioprocessing challenges.

Bioventus

3i Nanotech

Crunchbase Website Twitter Facebook Linkedin

3i Nanotech develops point-of-care platform technology to track protein biomarkers in human samples.

Bioventus

LiRA Global

Crunchbase Website Twitter Facebook Linkedin

LiRA Global is a developer of lip-reading technology.

Bioventus

Vitality Robotics

Crunchbase Website Twitter Facebook Linkedin

Vitality Robotics is a medical device company that designs AI-powered devices for biomedical research and veterinary medicine.

Bioventus

Vital Motion

Crunchbase Website Twitter Facebook Linkedin

Vital Motion is a medical device company that conducted its own proprietary home-clinical study using prototype devices.

Bioventus

Syntervention

Crunchbase Website Twitter Facebook Linkedin

Syntervention designs, develops and distributes products to eliminate preventable contamination during invasive medical procedures.

Bioventus

Protect3d

Crunchbase Website Twitter Facebook Linkedin

Protect3d is a leveraging 3D technologies to bring custom protective devices to athletes and competitors everywhere.

Bioventus

MicroElastic Ultrasound Systems, Inc.

Crunchbase Website Twitter Facebook Linkedin

Bringing low-cost handheld elastography to the point-of-care

Bioventus

Luvaura

Crunchbase Website Twitter Facebook Linkedin

Luvaura develops methods and medical devices designed to treat veins.

Bioventus

Curo Health Services

Crunchbase Website Twitter Facebook Linkedin

Curo Health Services is a hospice care company offering medical care, pain management, and emotional and spiritual support to families.

Bioventus

Aeroflow

Crunchbase Website Twitter Facebook Linkedin

Aeroflow Healthcare is recognized as a premier provider of durable medical equipment (DME).

Bioventus

Chiltern International

Crunchbase Website Twitter Facebook Linkedin

Chiltern International Limited, a contract research organization, provides clinical development, scientific services.

Bioventus

A LaRue Company

Crunchbase Website Twitter Facebook Linkedin

A LaRue Company is a business that plans to create, develop, and sell medical equipment.

Bioventus

Agile EndoSurgery

Crunchbase Website Twitter Facebook Linkedin

Agile EndoSurgery is a developer of articulated surgical instruments to expand the scope of minimally invasive surgery.

Bioventus

Lucem Health

Crunchbase Website Twitter Facebook Linkedin

Lucem Health develops a remote diagnostics platform designed to connect remote patient telemetry and biosensing devices with AI algorithms.

Bioventus

HekeTiss

Crunchbase Website Twitter Facebook Linkedin

HekeTiss developed TrophiPatch, a pharma solution for patients affected by non-healing chronic wounds.

Bioventus

Caia

Crunchbase Website Twitter Facebook Linkedin

Caia is a hand-held medical device company that simplifies breast self exams.

Bioventus

Physicians Own Pharmacy

Crunchbase Website Twitter Facebook Linkedin

Physicians Own Pharmacy develops medical devices and pharmaceuticals for the healthcare industry.

Bioventus

No Mess SPF

Crunchbase Website Twitter Facebook Linkedin

No Mess SPF is a medical device company that provides automatic sun protection solutions.

Bioventus

Global Medical Imaging

Crunchbase Website Twitter Facebook Linkedin

A Charlotte, N.C.-based provider of ultrasound and nuclear medicine sales and services

Bioventus

US Radiology Specialists

Crunchbase Website Twitter Facebook Linkedin

US Radiology is one of the largest and most progressive radiology groups in the country.

Bioventus

Blur

Crunchbase Website Twitter Facebook Linkedin

Blur is an innovation and product development consulting firm.

Bioventus

MxBiodevices

Crunchbase Website Twitter Facebook Linkedin

Mx Biodevices develops and commercializes an injectable nanoscaffold for the treatment of diabetic foot ulcers and other chronic wounds.

Bioventus

Medical Manufacturing Technologies

Crunchbase Website Twitter Facebook Linkedin

Medical Manufacturing Technologies designs, manufactures, and services medical product machinery.

Bioventus

Avioq

Crunchbase Website Twitter Facebook Linkedin

Avioq dedicated to creating medical products and providing highly flexible contract manufacturing services.

Bioventus

SunTech Medical

Crunchbase Website Twitter Facebook Linkedin

SunTech Medical provides blood pressure monitoring products and technologies.

Bioventus

Saebo

Crunchbase Website Twitter Facebook Linkedin

Saebo is a global provider of evidenced-based therapy solutions.

Bioventus

ATEX Technologies

Crunchbase Website Twitter Facebook Linkedin

ATEX Technologies designs, develop and manufactures implantable textiles components for medical devices in the healthcare industry.

Bioventus

Polyzen

Crunchbase Website Twitter Facebook Linkedin

Polyzen is a developer and manufacturer of customized polymer-based materials, films, components, and assemblies.

Bioventus

ecoTEKindustries

Crunchbase Website Twitter Facebook Linkedin

EcoTEKindustries is a manufacturer of carbon fiber and fiberglass in prosthetic and orthotic devices using natural materials.

Bioventus

FaceTouchUp

Crunchbase Website Twitter Facebook Linkedin

FaceTouchUp is an easy-to-use, affordable Plastic Surgery Simulator that helps surgeons visualize before-and-after surgery results.

Bioventus

mign

Crunchbase Website Twitter Facebook Linkedin

Mign is a medical device design for precision and sensitivity.

Bioventus

AccuMED Corp.

Crunchbase Website Twitter Facebook Linkedin

AccuMED Corp. is a medical devices company offering surgery devices and primary care equipment.

Bioventus

Precision Concepts Group

Crunchbase Website Twitter Facebook Linkedin

Precision Concepts Group is an engineering based single source provider of precision metal stampings located in Winston Salem.

Bioventus

InstantGMP

Crunchbase Website Twitter Facebook Linkedin

InstantGMP provides manufacturing and compliance solutions to companies within certain industries regulated by the FDA.

Bioventus

MyKare

Crunchbase Website Twitter Facebook Linkedin

MyKare is an intuitive suction device allowing users to easily irrigate and remove secretions from a baby’s nostrils.

Bioventus

Kapstone Medical

Crunchbase Website Twitter Facebook Linkedin

Kapstone is a medical device focused service provider for engineering, quality, regulatory, IP strategy, and manufacturing.

Bioventus

Pattons Medical

Crunchbase Website Twitter Facebook Linkedin

Pattons Medical manufactures air and vacuum systems for healthcare.

Bioventus

CS Medical

Crunchbase Website Twitter Facebook Linkedin

CS Medical is a developer, manufacturer, and marketer of medical devices.

Bioventus

CMP Pharma

Crunchbase Website Twitter Facebook Linkedin

CMP Pharma is a pharmaceutical company that provides niche solid and liquid drugs for acute health care treatment.

Bioventus

AmeriGlide

Crunchbase Website Twitter Facebook Linkedin

AmeriGlide is a leading distributor of home medical equipment. They offer a complete line of quality stair lifts, wheelchair lifts,

Bioventus

Hemo bioscience

Crunchbase Website Twitter Facebook Linkedin

Hemo bioscience is a medical device manufacturing company.

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