101 Best Missouri Software Companies and Startups

August 9, 2021
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This article showcases our top picks for the best Missouri based Software companies. These startups and companies are taking a variety of approaches to innovating the Software industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Missouri Software Startups

Data sourced from Crunchbase and SemRush.

Balto

Balto

Crunchbase Website Twitter Facebook Linkedin

Increase conversions, deliver a world-class customer experience, and decrease ramp time with Balto’s real-time guidance for contact centers.

Mycroft

Mycroft

Crunchbase Website Twitter Facebook Linkedin

Mycroft is a developer of an open source voice assistant platform designed to handle operating systems.

Mycroft

Adalo

Crunchbase Website Twitter Facebook Linkedin

Adalo is a computer software company that specializes in the fields of Android, software, and information technology.

Mycroft

Daupler

Crunchbase Website Twitter Facebook Linkedin

Daupler simplifies the way people communicate with local government and utilities.

Mycroft

Capacity

Crunchbase Website Twitter Facebook Linkedin

Capacity is an AI-powered helpdesk that automates support for customers and employees.

Mycroft

BriteCore

Crunchbase Website Twitter Facebook Linkedin

BriteCore is an enterprise-level insurance processing suite that combines core, data, and digital solutions into a single platform.

Mycroft

Curate

Crunchbase Website Twitter Facebook Linkedin

Curate provides end-to-end event, COGS, and rental management services.

Mycroft

Bonfyre

Crunchbase Website Twitter Facebook Linkedin

Bonfyre is a workplace culture platform that builds human connections in a remote workforce.

Mycroft

Essence Group Holdings

Crunchbase Website Twitter Facebook Linkedin

Essence Group Holdings offers health insurance and software solutions necessary for health systems, health plans and provider organizations.

Mycroft

Denim Social

Crunchbase Website Twitter Facebook Linkedin

Denim Social provides social media management and marketing automation software for customers.

Mycroft

Textel

Crunchbase Website Twitter Facebook Linkedin

Textel offers a business texting technology that allows businesses to text their customers on their existing business phone numbers.

Mycroft

Coolfire

Crunchbase Website Twitter Facebook Linkedin

Coolfire provides connected workstream collaboration software to enhance real-time event awareness, control, and response.

Mycroft

Simplifyy

Crunchbase Website Twitter Facebook Linkedin

SaaS, Multifamily Technology, Proptech, RentTech

Mycroft

DisruptOps

Crunchbase Website Twitter Facebook Linkedin

DisruptOps is a cloud security operations platform that helps customers find & fix security issues before they become incidents.

Mycroft

SpiderOak

Crunchbase Website Twitter Facebook Linkedin

SpiderOak is a collaboration tool that develops a technology that eliminates entire categories of cyberattacks.

Mycroft

Paytient

Crunchbase Website Twitter Facebook Linkedin

Paytient is an employer-sponsored payer of employee out-of-pocket medical, dental, pharmacy, vision, or veterinary expenses.

Mycroft

FUGA

Crunchbase Website Twitter Facebook Linkedin

FUGA is the high-end technology partner for content owners and distributors.

Mycroft

Healthcare Fraud Shield

Crunchbase Website Twitter Facebook Linkedin

Healthcare Fraud Shield is a provider of dynamic fraud, waste and abuse detection software solution.

Mycroft

Neocova

Crunchbase Website Twitter Facebook Linkedin

Neocova is a financial services company that specializes in providing artificial intelligence, analytics, and other cloud-based systems.

Mycroft

SentiAR

Crunchbase Website Twitter Facebook Linkedin

Digital health company with holographic AR platform for intraprocedural clinical use.

Mycroft

Benchmark Email

Crunchbase Website Twitter Facebook Linkedin

Benchmark Email is a digital marketing company that specializes in email messaging and communication.

Mycroft

Boundless Spatial

Crunchbase Website Twitter Facebook Linkedin

Boundless is a provider of open source product support, training, and core development to meet geospatial requirements.

Mycroft

Aspire Software

Crunchbase Website Twitter Facebook Linkedin

Aspire Software develops business management software for landscaping, snow and ice management, and construction businesses.

Mycroft

BenchmarkONE

Crunchbase Website Twitter Facebook Linkedin

BenchmarkONE develops software that automates sales and marketing activities to enable businesses to reach and retain customers.

Mycroft

Pepper

Crunchbase Website Twitter Facebook Linkedin

Pepper offers an operating system and service delivery platform to empower enterprises to deploy sophisticated IoT marketplace solutions.

Mycroft

TopOPPS

Crunchbase Website Twitter Facebook Linkedin

Artificial Intelligence for Sales Forecasting and Pipeline Management

Mycroft

ZAF Energy Systems

Crunchbase Website Twitter Facebook Linkedin

ZAF Energy Systems develops battery technology that is safe, high in energy, low in cost and weight, and environment friendly.

Mycroft

Amdocs

Crunchbase Website Twitter Facebook Linkedin

Amdocs is a developer and provider of customer experience systems for communications, media, and entertainment industries.

Mycroft

Aker Technologies

Crunchbase Website Twitter Facebook Linkedin

Aker is an agriculture data company providing crop intelligence and in-season analytics.

Mycroft

Cerner

Crunchbase Website Twitter Facebook Linkedin

Cerner Corporation is a supplier of healthcare information technology solutions, services, devices and hardware.

Mycroft

Homebase

Crunchbase Website Twitter Facebook Linkedin

Your solution for smart apartment management and residence experience.

Mycroft

Tallyfy

Crunchbase Website Twitter Facebook Linkedin

Tallyfy is beautiful workflow software that lets you document, track and improve all your repeatable processes

Mycroft

Ryvit

Crunchbase Website Twitter Facebook Linkedin

Ryvit develops an integration software that delivers seamless flow of data between premise and software used in the construction industry.

Mycroft

Disruptel

Crunchbase Website Twitter Facebook Linkedin

Disruptel is a visually-aware artificial intelligence that understands image and video content.

Mycroft

Mission Control

Crunchbase Website Twitter Facebook Linkedin

Mission Control is a developer of an eSports platform used to create recreational gaming leagues for friends.

Mycroft

Strayos

Crunchbase Website Twitter Facebook Linkedin

Strayos is a 3D aerial intelligence platform for Mining and Quarry blasting operations to reduce cost.

Mycroft

Exegy

Crunchbase Website Twitter Facebook Linkedin

Exegy provides ultra-high performance, hardware-accelerated computing appliances that process market data for financial organizations.

Mycroft

Compatio

Crunchbase Website Twitter Facebook Linkedin

Compatio is a software company that specializes in eCommerce, recommendation systems, store-branded apps, and retail software.

Mycroft

Advocado

Crunchbase Website Twitter Facebook Linkedin

Advocado is a real-time cross-media optimization & audience platform that makes advertising perform better.

Mycroft

NeuroLutions

Crunchbase Website Twitter Facebook Linkedin

The Company seeks to develop a revolutionary platform of devices, based on Brain Computer Interface (BCI) technology

Mycroft

MindMixer

Crunchbase Website Twitter Facebook Linkedin

MindMixer helps communities grow their networks of engaged residents through easy-to-use online engagement software.

Mycroft

Well Principled

Crunchbase Website Twitter Facebook Linkedin

Well Principled is an A.I. Management Consultant that predicts the buying behavior of every customer.

Mycroft

LendingStandard

Crunchbase Website Twitter Facebook Linkedin

LendingStandard improves a lender’s ability to aquire, process, and fund a complex commercial loan transaction.

Mycroft

NEER

Crunchbase Website Twitter Facebook Linkedin

Redefining Water Infrastructure Modeling and Asset Management through Machine Learning

Mycroft

TRIBUS

Crunchbase Website Twitter Facebook Linkedin

TRIBUS provides technology, strategy, marketing and operations solutions for real estate brokerages around the world.

Mycroft

PolicyEngage

Crunchbase Website Twitter Facebook Linkedin

Workflow Automation Software for Public Affairs. Connect legislative & regulatory tracking, advocate & donor engagement, & media monitoring.

Mycroft

Epharmix

Crunchbase Website Twitter Facebook Linkedin

Epharmix is a digital healthcare company that creates clinically validated and condition-specific communication tools.

Mycroft

DivvyHQ

Crunchbase Website Twitter Facebook Linkedin

DivvyHQ is a cloud-based, content planning, workflow, and collaboration platform.

Mycroft

SwipeSum

Crunchbase Website Twitter Facebook Linkedin

At SwipeSum we are software-enabled payments consultants leveraging our proprietary software, Staitment. We’re your Chief Payments Officer.

Mycroft

TruQC

Crunchbase Website Twitter Facebook Linkedin

TruQC is a cloud-based industrial painting quality control and documentation application for the iPad.

Mycroft

HealthMEDX

Crunchbase Website Twitter Facebook Linkedin

HealthMEDX, Inc. offers home care, long-term care, and rehab software solutions. It offers CareMEDX, a suite of knowledge management.

Mycroft

eHawk

Crunchbase Website Twitter Facebook Linkedin

eHawk is a monitoring platform that helps supervise criminal defendants.

Mycroft

Pathfinder Health Innovations

Crunchbase Website Twitter Facebook Linkedin

Pathfinder Health Innovations is a comprehensive web-based software tool for supporting the implementation of ABA therapy.

Mycroft

homewav

Crunchbase Website Twitter Facebook Linkedin

Homewav is the leader in providing reliable revenue to detention facilities with comprehensive inmate video visitation solutions & hardware.

Mycroft

Remetrik

Crunchbase Website Twitter Facebook Linkedin

Better Royalty/Analytics/Data Software for Music Businesses

Mycroft

Banks Best Rates

Crunchbase Website Twitter Facebook Linkedin

Tech Financial Organization

Mycroft

FitBark

Crunchbase Website Twitter Facebook Linkedin

FitBark provides dog parents and pet care brands with deep, actionable insights into dog health and behavior.

Mycroft

gomingo

Crunchbase Website Twitter Facebook Linkedin

Manufacturing analytics application that analyzes data from the factory floor to provide key metrics to improve performance and uptime

Mycroft

Rovertown

Crunchbase Website Twitter Facebook Linkedin

Rovertown builds branded apps for c-stores looking to better connect with customers in an always-on world.

Mycroft

Foresite Healthcare

Crunchbase Website Twitter Facebook Linkedin

Foresite Healthcare is a provider of healthcare technology solutions to healthcare professionals.

Mycroft

Qpass

Crunchbase Website Twitter Facebook Linkedin

Qpass is a U.S.-based software provider that provides full cycle of activities for business systems and value-added data services.

Mycroft

Automotive Innovations

Crunchbase Website Twitter Facebook Linkedin

Automotive Innovations builds software in the automotive industry that gives dealers actionable intelligent information.

Mycroft

FocalCast

Crunchbase Website Twitter Facebook Linkedin

Live qualitative research platform with no downloads or plugins

Mycroft

Keybot

Crunchbase Website Twitter Facebook Linkedin

Keybot is a smart rental access Robot that automates access for rental properties.

Mycroft

Rebate Bus, Inc.

Crunchbase Website Twitter Facebook Linkedin

Rebate Bus provides software and support to business customers promoting the sale and implementation of energy-efficient products.

Mycroft

Jack Henry & Associates

Crunchbase Website Twitter Facebook Linkedin

Jack Henry & Associates, Inc. provides integrated computer systems for in-house and outsourced data processing to commercial banks.

Mycroft

Radialogica

Crunchbase Website Twitter Facebook Linkedin

Radialogica is a bioinformatics company providing software solutions for radiation oncology and the healthcare market.

Mycroft

PopBookings

Crunchbase Website Twitter Facebook Linkedin

PopBookings is a cloud-based software that automates the hiring process for temporary and promotional staffing companies.

Mycroft

PlanIT Impact

Crunchbase Website Twitter Facebook Linkedin

PlanIT Impact is a cloud-based web application that allows architects, designers, engineers, developers.

Mycroft

AppsCo Inc

Crunchbase Website Twitter Facebook Linkedin

Appsco helps you manage access to your company applications and gives you meaningful insights over sensitive data flow.

Mycroft

Emerson

Crunchbase Website Twitter Facebook Linkedin

Emerson is a global technology & engineering company providing innovative solutions for customers in industrial and residential markets.

Mycroft

HIPAAtrek

Crunchbase Website Twitter Facebook Linkedin

HIPAA compliance is a long journey. We are just the guides to help your organization on that trek!

Mycroft

Recursive Labs

Crunchbase Website Twitter Facebook Linkedin

We improve customer sales & service experiences (CX) with a fully integrated, visual customer engagement platform for web, mobile & IoT

Mycroft

FloEnvy

Crunchbase Website Twitter Facebook Linkedin

FloEnvy is the premier software for cannabis cultivation

Mycroft

RF Controls

Crunchbase Website Twitter Facebook Linkedin

RF Controls is uniquely positioned to usher in the Internet of Everything era.

Mycroft

TrackMy Solutions

Crunchbase Website Twitter Facebook Linkedin

TrackMy Solutions is a software and mobile application company that provides a solution for people with medical implants.

Mycroft

Car-Part.com

Crunchbase Website Twitter Facebook Linkedin

Provider of web solutions for auto recyclers in areas such as inventory searching, web design and hosting etc.

Mycroft

Cloud Commerce

Crunchbase Website Twitter Facebook Linkedin

Cloud Products and Services for SMBs.

Mycroft

World Wide Technology

Crunchbase Website Twitter Facebook Linkedin

World Wide Technology is a systems integrator, provides information technology and supply chain solutions.

Mycroft

AppNotch

Crunchbase Website Twitter Facebook Linkedin

AppNotch provides individuals and companies with a resource to manufacture apps without software.

Mycroft

DSI®

Crunchbase Website Twitter Facebook Linkedin

Cloud Inventory® Solutions and Mobile-First Supply Chain Apps for the Digital Economy.

Mycroft

pikazo

Crunchbase Website Twitter Facebook Linkedin

Pikazo is at the very bleeding edge of neural network software

Mycroft

StockSwap

Crunchbase Website Twitter Facebook Linkedin

StockSwap is a mobile app that allows users to share stock trades, thoughts, and repost news articles with friends and other users.

Mycroft

Brightergy

Crunchbase Website Twitter Facebook Linkedin

Brightergy is a new kind of energy company that empowers organizations to take control over their energy – creation, cost, and consumption.

Mycroft

NOUS Imaging

Crunchbase Website Twitter Facebook Linkedin

NOUS Imaging is a St. Louis-based startup has created a software-based biofeedback solution

Mycroft

FIRMM

Crunchbase Website Twitter Facebook Linkedin

FIRMM is a real-time MRI quality metrics to reduce costs and improve quality. Jointly developed by the Fair (OHSU) & Dosenbach (WashU) labs.

Mycroft

HomeTraq

Crunchbase Website Twitter Facebook Linkedin

HomeTraq is an online brokerage platform that connects potential homebuyer with a local real agent as well as schedules property showings.

Mycroft

Deep Water Software

Crunchbase Website Twitter Facebook Linkedin

Email Receipt Pictures. Get Reports. Retailing Simplified.

Mycroft

SmashToast, Inc.

Crunchbase Website Twitter Facebook Linkedin

Control your home from your phone.

Mycroft

BlueStrata EHR

Crunchbase Website Twitter Facebook Linkedin

BlueStrata EHR provides simple and reliable solutions to long term care facilities giving them the opportunity

Mycroft

Bridge Software LLC

Crunchbase Website Twitter Facebook Linkedin

Developer of Stagistics – cloud-based software and data aggregator connecting the home renovation industry to improve results for all

Mycroft

Truckily

Crunchbase Website Twitter Facebook Linkedin

Truckily is a mobile application that enables users to find food trucks in their local community.

Mycroft

MetKnow, Inc.

Crunchbase Website Twitter Facebook Linkedin

MetKnow is a patented flash card and quizzing application that helps members in organizations learn each other’s name.

Mycroft

Graematter

Crunchbase Website Twitter Facebook Linkedin

Graematter offers a regulatory intelligence system that enables regulatory professionals to locate, analyze, and track related information.

Mycroft

WayLit

Crunchbase Website Twitter Facebook Linkedin

WayLit provides immigration services based on Artificial Intelligence technology.

Mycroft

SlideBatch

Crunchbase Website Twitter Facebook Linkedin

SlideBatch is an innovative new product that cuts through content overload on the web with a simple concept of a “Batch”.

Mycroft

Mediprocity

Crunchbase Website Twitter Facebook Linkedin

Mediprocity is a mobile app that provides secure messaging services for the healthcare industry.

Mycroft

Blossom

Crunchbase Website Twitter Facebook Linkedin

Blossom is a software company that connects all types of exchanges on the same marketplace.

Mycroft

Yurbuds

Crunchbase Website Twitter Facebook Linkedin

Yurbuds develops a type of sport earphones that are custom fit for athletes, runners and music lovers.

Mycroft

GIVVER

Crunchbase Website Twitter Facebook Linkedin

GIVVER provides a solution that enables users to tweet a donation to their organizations and causes.

Mycroft

Deck Internet Solutions

Crunchbase Website Twitter Facebook Linkedin

Deck Internet Solutions is a cloud-based management platform that provides a better solution to the customer to become an eCommerce leader.

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