101 Best Missouri Non Profit Companies and Startups

August 9, 2021
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This article showcases our top picks for the best Missouri based Non Profit companies. These startups and companies are taking a variety of approaches to innovating the Non Profit industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Missouri Non Profit Startups

Data sourced from Crunchbase and SemRush.

Donald Danforth Plant Science Center

Donald Danforth Plant Science Center

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Donald Danforth Plant Science Center is a non-profit research institute developing plant science solutions to improve human conditions.

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LaunchCode

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LaunchCode is an organization that creates pathways to economic opportunity and upward mobility.

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Water.org

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Water.org, a non-profit organization providing aid to developing countries that do not have access to safe drinking water and sanitation.

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Ascension Health

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Largest non-profit health system in the United States.

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Urban League of Metropolitan St. Louis

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The Urban League of Metropolitan St. Louis is a social service and civil rights organization.

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MathBRIX

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MathBRIX is a highly visual, concept-based approach to teaching math, backed by decades of research.

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The Muny

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The Muny is a non-profit organization whose mission is to enrich lives by producing exceptional, accessible musical theatre for all.

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St. Louis Children’s Hospital

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It is one of the best children’s hospitals in the country

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Brazen Global

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Brazen’s technology-enabled membership platform offers customized resources and a global support.

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Equis Hospitality Mangagement

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EQUIS is one of the leading hospitality firms

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BJC HealthCare

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BJC HealthCare is a non-profit health care organization based in St. Louis, Missouri.

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BioNexus KC

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BioNexus KC focuses on making the Kansas City region the world leader at the nexus of animal and human health, benefiting all citizens.

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Mercy

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Mercy is the fifth largest Catholic health care system in the U.S. serving millions of people annually.

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Meramec Regional Planning Commission

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Meramec Regional Planning Commission is a voluntary council of local governments serving the Missouri Meramec area.

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Green Hills Regional Planning Commission

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Green Hills Regional Planning Commission is operating as a sub-state planning and development agency serving the State of Missouri.

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Jewish Family Service of Western Massachusetts

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Jewish Family Service of Western Massachusetts works with individuals and families of all races and religions

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Boonslick Regional Planning Commission

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Boonslick Regional Planning Commission provides the community, economic, and workforce development initiatives.

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Habitat for Humanity of Springfield

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Habitat for Humanity of Springfield seeks to put God’s love into action by building homes, communities and hope.

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TNO

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TNO is an independent innovation organization. We connect people and knowledge to create innovations that strengthen competitiveness.

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DevelopSpringfield

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DevelopSpringfield serves as a catalyst for public and private investment and economic revitalization in the City of Springfield.

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Loop Trolley

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In 1997, a community planning group engaged in a collaborative process with the City of St.

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Southeast Missouri Regional Planning & Economic Development Commission

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Southeast Missouri Regional Planning & Economic Development Commission is offers planning and economic development services.

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Novus International

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Novus International, Inc., headquartered in metro St. Louis, Missouri, U.S.

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Equity.com

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Equity.com is a new type of technology investment fund.

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Base Academy of Music

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Base Academy of Music is a non-profit music organization.

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Mid-Missouri Regional Planning Commission

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Mid-Missouri Regional Planning Commission is delivering a variety of federal, state, and local programs.

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Generation Prodigy

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Generation Prodigy is a non-profit organization committed to developing and supporting inner-city students from low-income families.

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Pulitzer Inc.

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Pulitzer Inc. owned newspapers, television stations, and radio stations across the United States.

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Northeast Missouri Regional Planning Commission

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Northeast Missouri Regional Planning Commission is one of nineteen regional planning commissions in the State of Missouri.

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UNA Purchasing Solutions

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The nation’s fastest growing Group Purchasing Organization .

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Barnes-Jewish Hospital

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Barnes Jewish Hospital and medical center in St Louis Missouri has established a rich tradition of medical excellence

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Saint Luke’s Health System

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Saint Luke’s Health System is a faith-based, not-for-profit aligned health system

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Together CREDIT UNION

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Together CREDIT UNION is a community-based not-for-profit financial institution.

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American Optometric Association

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American Optometric Association is the acknowledged leader and recognized authority for eye and vision care in the world.

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WeCode KC

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WeCode KC focuses on creating a pipeline of future-ready professionals.

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First Hand Foundation

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First Hand Foundation, a non-profit foundation that provides assistance to children with critical health care needs.

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Concordia Plans

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Concordia Plans is a not-for-profit organization that offers employee benefit solutions covering health, disability, life and retirement.

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Enactus USA

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Enactus is an experiential learning platform dedicated to creating the next generation of entrepreneurial leaders and social innovators.

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Open Source Ecology

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Open Source Ecology is developing open-source industrial machines that can be made for a fraction of commercial costs & sharing our designs.

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National Wood Flooring Association

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National Wood Flooring Association is a trading company that deals with technical support, networking and education regarding wood flooring.

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Missouri Partnership

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Missouri Partnership is an economic development organization that offers international investments and health innovation solution services.

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Acumen Consulting

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Acumen Consulting is an information technology solutions provider to businesses, not-for-profit organizations, and government agencies.

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United Credit Union

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United Credit Union is a non-profit organization that offers its members financial support, loans, credit and assistance.

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Foundation for Intentional Community

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Foundation for Intentional Community is a nonprofit organization that supports and assists the development of intentional communities.

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Central Electric Power Cooperative

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Central Electric Power Cooperative is a nonprofit firm that specializes in electric power transmission, distribution and marketing services.

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Wired Impact

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Building websites for nonprofits and writing about how nonprofits can use the web more effectively.

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BluCurrent Credit Union

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BluCurrent Credit Union provides affordable financial services to individuals.

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Bi-State Development

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Bi-State Development is a dynamic resource for economic development.

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Western Equipment Dealers Association

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WEDA, an International trade association that represents agricultural, industrial & outdoor power equipment dealers.

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River Region Credit Union

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River Region Credit Union is a member-owned financial cooperative that provides financial assistance and education.

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Saving Sight

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Saving Sight is a nonprofit organization with a mission to change lives by saving sight.

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Ohio Tuition Trust Authority

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Ohio Tuition Trust Authority is a state government agency that provides College Savings, Financial services and 529 Plans.

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United Soybean Board

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United Soybean Board specializes on maximizing the profit opportunities for all soybean farmers.

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Liguori Publications

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Liguori Publications is a publisher of Catholic books and products for the parish.

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The Mission Continues

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The Mission Continues empowers veterans facing the challenge of adjusting to life at home to find new missions.

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Burrell Behavioral Health

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Burrell Behavioral Health is an autism & neuropsychology health center that offers mental health needs, counseling, & psychiatric services.

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Nonprofit Leadership Alliance

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Formerly American Humanics are a national alliance of colleges, universities, and nonprofit organizations.

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D and K interprises

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We are starting coin operated breathalyzers in Missouri. CNN quotes it to be the next best novelty in years. The machines are almost .

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Veterans of Foreign Wars

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Veterans of Foreign Wars is a war veterans organization.

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Nurses For Newborns

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Nurses For Newborns is a children care charity that specializes in-home nursing visits that offers healthcare services and parenting skills.

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Public School Retirement System of the City of St. Louis

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Public School Retirement System of the City of St. Louis provides retirement, disability, death, and survivor benefits for its employees.

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Lighthouse for the Blind-Saint Louis

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Lighthouse for the Blind-Saint Louis is a not-for-profit manufacturing and packaging company.

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Mosaic Life Care

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Mosaic Life Care is a nonprofit organization that expertise in healthcare, wellness, clinic care and health information management services.

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Cedar County Memorial Hospital

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Cedar County Memorial Hospital provides healthcare services in Cedar County.

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MERS Missouri Goodwill Industries

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MERS Missouri Goodwill Industries provides career counseling, skills training, education, and employment services.

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The State Bank

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The State Bank is a local bank serving the region of Michigan.

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Greater Kansas City Community Foundation

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Greater Kansas City Community Foundation is a non profit organisation.

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PCs for People

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PCs for People is a non-profit organization that offers computer recycling, tax preparation assistance and internet solutions.

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Truman Library Institute

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Truman Library Institute is the member-supported, nonprofit partner of the Truman library.

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GlobalHack

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Drives social impact through technology.

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Habitat For Humanity of Kansas City

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Habitat For Humanity of Kansas City is a nonprofit organization that provides affordable homes for people within the region.

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Second Harvest Heartland

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Second Harvest Heartland believes no one should ever go hungry, as our region produces more than enough food for everyone.

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Missouri Highlands Health Care

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Missouri Highlands Health Care is a non-profit organization that offers dental, nutritionist, preventative care and behavioral services.

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Prosperity Connection

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Prosperity Connection offers free financial coaching and money management education.

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MOCSA

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MOCSA improves the lives of those impacted by sexual abuse and assault.

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My Father’s World

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My Father’s World is an educational company specializes in life-transforming, academic excellence with a Christian worldview.

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Cornerstones of Care

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Cornerstones of Care provide quality prevention, treatment and support services to children and families.

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American Society of News Editors (ASNE)

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The American Society of News Editors focuses on leadership development and journalism-related issues.

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Grand Rapids Mag

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The Grand Rapids Area Chamber of Commerce is the voice of West Michigan business and the premier business membership organization

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Legal Aid of Western Missouri

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Legal Aid of Western Missouri is a nonprofit organization that offers free civil non-criminal legal services for destitute people.

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SocioDB

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Your Community At Your Fingertips.

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Southeast Missouri Food Bank

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Southeast Missouri Food Bank is an organization that donates food for charity and disaster relief programs.

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St. Louis Arc

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The St. Louis Arc is a non-profit agency that provides support to adults and children with intellectual and developmental disabilities

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Kansas City Repertory Theatre

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Kansas City Repertory Theatre pursues theatrical excellence and advances the art form.

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Saint Francis Healthcare

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Saint Francis Healthcare is a nonprofit community that offers surgery, emergency nursing and urgent care facility services.

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Children International

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Children International is a humanitarian organization that focuses on providing high-impact programs to children and adults to end poverty.

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World Federation of Orthodontists

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The goal of the World Federation of Orthodontists is to advance the art and science of orthodontics worldwide.

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Prepare.ai

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Prepare.ai is a non-profit organization that brings artificial intelligence into your personal life and workplace.

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First Missouri Credit Union

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First Missouri Credit Union is a non-profit financial cooperative that offers financial services to credit union members.

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Nine PBS

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Nine PBS is a nonprofit organization & broadcast channel that specializes in magazine publishing, media production & entertainment services.

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Varsity Esports Foundation, Inc.

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A 501(c)(3) organization established to assist schools and students to reach their potential through gaming and Esports communities.

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GoodMap

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GoodMap mission is to help service providers find, organize and share community resource information.

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Creative Reaction Lab

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Creative Reaction Lab is a nonprofit organization focus on community development programs and apprenticeship mentoring services.

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Independence Center

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Independence Center is a nonprofit organization that provides rehabilitation programs, mental illness and behavioral healthcare services.

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Givable

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Givable is a nonprofit organization.

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EducationPlus

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EducationPlus is a non-profit educational service agency that provides leadership & resources to support learning & innovation to students.

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Ray County Memorial Hospital

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Ray County Memorial Hospital offers radiology, oncology, physiotherapy, out patient clinic, nutrition and cardiac rehab services.

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Investigative Reporters and Editors

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Investigative Reporters and Editors is a grassroots nonprofit organization dedicated to improving the quality of investigative reporting.

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White River Valley Electric

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The White River Valley Electric’s aim is straightforward: to ensure that members have safe and dependable electric service in their homes.

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Kansas City Credit Union

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Kansas City Credit Union is a non-profit member-owned financial institution offering financial services.

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Missouri Delta Medical Center

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Missouri Delta Medical Center provides behavioral health, cancer care, cardiology, diagnostic imaging and cardiac rehabilitation services.

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