This article showcases our top picks for the best Missouri based Non Profit companies. These startups and companies are taking a variety of approaches to innovating the Non Profit industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top Missouri Non Profit Startups
Data sourced from Crunchbase and SemRush.
Donald Danforth Plant Science Center
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Donald Danforth Plant Science Center is a non-profit research institute developing plant science solutions to improve human conditions.
LaunchCode
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LaunchCode is an organization that creates pathways to economic opportunity and upward mobility.
Water.org
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Water.org, a non-profit organization providing aid to developing countries that do not have access to safe drinking water and sanitation.
Ascension Health
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Largest non-profit health system in the United States.
Urban League of Metropolitan St. Louis
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The Urban League of Metropolitan St. Louis is a social service and civil rights organization.
MathBRIX
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MathBRIX is a highly visual, concept-based approach to teaching math, backed by decades of research.
The Muny
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The Muny is a non-profit organization whose mission is to enrich lives by producing exceptional, accessible musical theatre for all.
St. Louis Children’s Hospital
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It is one of the best children’s hospitals in the country
Brazen Global
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Brazen’s technology-enabled membership platform offers customized resources and a global support.
Equis Hospitality Mangagement
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EQUIS is one of the leading hospitality firms
BJC HealthCare
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BJC HealthCare is a non-profit health care organization based in St. Louis, Missouri.
BioNexus KC
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BioNexus KC focuses on making the Kansas City region the world leader at the nexus of animal and human health, benefiting all citizens.
Mercy
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Mercy is the fifth largest Catholic health care system in the U.S. serving millions of people annually.
Meramec Regional Planning Commission
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Meramec Regional Planning Commission is a voluntary council of local governments serving the Missouri Meramec area.
Green Hills Regional Planning Commission
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Green Hills Regional Planning Commission is operating as a sub-state planning and development agency serving the State of Missouri.
Jewish Family Service of Western Massachusetts
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Jewish Family Service of Western Massachusetts works with individuals and families of all races and religions
Boonslick Regional Planning Commission
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Boonslick Regional Planning Commission provides the community, economic, and workforce development initiatives.
Habitat for Humanity of Springfield
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Habitat for Humanity of Springfield seeks to put God’s love into action by building homes, communities and hope.
TNO
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TNO is an independent innovation organization. We connect people and knowledge to create innovations that strengthen competitiveness.
DevelopSpringfield
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DevelopSpringfield serves as a catalyst for public and private investment and economic revitalization in the City of Springfield.
Loop Trolley
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In 1997, a community planning group engaged in a collaborative process with the City of St.
Southeast Missouri Regional Planning & Economic Development Commission
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Southeast Missouri Regional Planning & Economic Development Commission is offers planning and economic development services.
Novus International
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Novus International, Inc., headquartered in metro St. Louis, Missouri, U.S.
Equity.com
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Equity.com is a new type of technology investment fund.
Base Academy of Music
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Base Academy of Music is a non-profit music organization.
Mid-Missouri Regional Planning Commission
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Mid-Missouri Regional Planning Commission is delivering a variety of federal, state, and local programs.
Generation Prodigy
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Generation Prodigy is a non-profit organization committed to developing and supporting inner-city students from low-income families.
Pulitzer Inc.
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Pulitzer Inc. owned newspapers, television stations, and radio stations across the United States.
Northeast Missouri Regional Planning Commission
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Northeast Missouri Regional Planning Commission is one of nineteen regional planning commissions in the State of Missouri.
UNA Purchasing Solutions
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The nation’s fastest growing Group Purchasing Organization .
Barnes-Jewish Hospital
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Barnes Jewish Hospital and medical center in St Louis Missouri has established a rich tradition of medical excellence
Saint Luke’s Health System
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Saint Luke’s Health System is a faith-based, not-for-profit aligned health system
Together CREDIT UNION
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Together CREDIT UNION is a community-based not-for-profit financial institution.
American Optometric Association
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American Optometric Association is the acknowledged leader and recognized authority for eye and vision care in the world.
WeCode KC
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WeCode KC focuses on creating a pipeline of future-ready professionals.
First Hand Foundation
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First Hand Foundation, a non-profit foundation that provides assistance to children with critical health care needs.
Concordia Plans
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Concordia Plans is a not-for-profit organization that offers employee benefit solutions covering health, disability, life and retirement.
Enactus USA
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Enactus is an experiential learning platform dedicated to creating the next generation of entrepreneurial leaders and social innovators.
Open Source Ecology
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Open Source Ecology is developing open-source industrial machines that can be made for a fraction of commercial costs & sharing our designs.
National Wood Flooring Association
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National Wood Flooring Association is a trading company that deals with technical support, networking and education regarding wood flooring.
Missouri Partnership
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Missouri Partnership is an economic development organization that offers international investments and health innovation solution services.
Acumen Consulting
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Acumen Consulting is an information technology solutions provider to businesses, not-for-profit organizations, and government agencies.
United Credit Union
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United Credit Union is a non-profit organization that offers its members financial support, loans, credit and assistance.
Foundation for Intentional Community
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Foundation for Intentional Community is a nonprofit organization that supports and assists the development of intentional communities.
Central Electric Power Cooperative
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Central Electric Power Cooperative is a nonprofit firm that specializes in electric power transmission, distribution and marketing services.
Wired Impact
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Building websites for nonprofits and writing about how nonprofits can use the web more effectively.
BluCurrent Credit Union
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BluCurrent Credit Union provides affordable financial services to individuals.
Bi-State Development
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Bi-State Development is a dynamic resource for economic development.
Western Equipment Dealers Association
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WEDA, an International trade association that represents agricultural, industrial & outdoor power equipment dealers.
River Region Credit Union
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River Region Credit Union is a member-owned financial cooperative that provides financial assistance and education.
Saving Sight
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Saving Sight is a nonprofit organization with a mission to change lives by saving sight.
Ohio Tuition Trust Authority
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Ohio Tuition Trust Authority is a state government agency that provides College Savings, Financial services and 529 Plans.
United Soybean Board
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United Soybean Board specializes on maximizing the profit opportunities for all soybean farmers.
Liguori Publications
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Liguori Publications is a publisher of Catholic books and products for the parish.
The Mission Continues
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The Mission Continues empowers veterans facing the challenge of adjusting to life at home to find new missions.
Burrell Behavioral Health
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Burrell Behavioral Health is an autism & neuropsychology health center that offers mental health needs, counseling, & psychiatric services.
Nonprofit Leadership Alliance
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Formerly American Humanics are a national alliance of colleges, universities, and nonprofit organizations.
D and K interprises
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We are starting coin operated breathalyzers in Missouri. CNN quotes it to be the next best novelty in years. The machines are almost .
Veterans of Foreign Wars
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Veterans of Foreign Wars is a war veterans organization.
Nurses For Newborns
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Nurses For Newborns is a children care charity that specializes in-home nursing visits that offers healthcare services and parenting skills.
Public School Retirement System of the City of St. Louis
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Public School Retirement System of the City of St. Louis provides retirement, disability, death, and survivor benefits for its employees.
Lighthouse for the Blind-Saint Louis
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Lighthouse for the Blind-Saint Louis is a not-for-profit manufacturing and packaging company.
Mosaic Life Care
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Mosaic Life Care is a nonprofit organization that expertise in healthcare, wellness, clinic care and health information management services.
Cedar County Memorial Hospital
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Cedar County Memorial Hospital provides healthcare services in Cedar County.
MERS Missouri Goodwill Industries
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MERS Missouri Goodwill Industries provides career counseling, skills training, education, and employment services.
The State Bank
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The State Bank is a local bank serving the region of Michigan.
Greater Kansas City Community Foundation
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Greater Kansas City Community Foundation is a non profit organisation.
PCs for People
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PCs for People is a non-profit organization that offers computer recycling, tax preparation assistance and internet solutions.
Truman Library Institute
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Truman Library Institute is the member-supported, nonprofit partner of the Truman library.
Habitat For Humanity of Kansas City
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Habitat For Humanity of Kansas City is a nonprofit organization that provides affordable homes for people within the region.
Second Harvest Heartland
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Second Harvest Heartland believes no one should ever go hungry, as our region produces more than enough food for everyone.
Missouri Highlands Health Care
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Missouri Highlands Health Care is a non-profit organization that offers dental, nutritionist, preventative care and behavioral services.
Prosperity Connection
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Prosperity Connection offers free financial coaching and money management education.
MOCSA
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MOCSA improves the lives of those impacted by sexual abuse and assault.
My Father’s World
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My Father’s World is an educational company specializes in life-transforming, academic excellence with a Christian worldview.
Cornerstones of Care
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Cornerstones of Care provide quality prevention, treatment and support services to children and families.
American Society of News Editors (ASNE)
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The American Society of News Editors focuses on leadership development and journalism-related issues.
Grand Rapids Mag
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The Grand Rapids Area Chamber of Commerce is the voice of West Michigan business and the premier business membership organization
Legal Aid of Western Missouri
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Legal Aid of Western Missouri is a nonprofit organization that offers free civil non-criminal legal services for destitute people.
Southeast Missouri Food Bank
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Southeast Missouri Food Bank is an organization that donates food for charity and disaster relief programs.
St. Louis Arc
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The St. Louis Arc is a non-profit agency that provides support to adults and children with intellectual and developmental disabilities
Kansas City Repertory Theatre
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Kansas City Repertory Theatre pursues theatrical excellence and advances the art form.
Saint Francis Healthcare
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Saint Francis Healthcare is a nonprofit community that offers surgery, emergency nursing and urgent care facility services.
Children International
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Children International is a humanitarian organization that focuses on providing high-impact programs to children and adults to end poverty.
World Federation of Orthodontists
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The goal of the World Federation of Orthodontists is to advance the art and science of orthodontics worldwide.
Prepare.ai
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Prepare.ai is a non-profit organization that brings artificial intelligence into your personal life and workplace.
First Missouri Credit Union
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First Missouri Credit Union is a non-profit financial cooperative that offers financial services to credit union members.
Nine PBS
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Nine PBS is a nonprofit organization & broadcast channel that specializes in magazine publishing, media production & entertainment services.
Varsity Esports Foundation, Inc.
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A 501(c)(3) organization established to assist schools and students to reach their potential through gaming and Esports communities.
GoodMap
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GoodMap mission is to help service providers find, organize and share community resource information.
Creative Reaction Lab
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Creative Reaction Lab is a nonprofit organization focus on community development programs and apprenticeship mentoring services.
Independence Center
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Independence Center is a nonprofit organization that provides rehabilitation programs, mental illness and behavioral healthcare services.
EducationPlus
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EducationPlus is a non-profit educational service agency that provides leadership & resources to support learning & innovation to students.
Ray County Memorial Hospital
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Ray County Memorial Hospital offers radiology, oncology, physiotherapy, out patient clinic, nutrition and cardiac rehab services.
Investigative Reporters and Editors
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Investigative Reporters and Editors is a grassroots nonprofit organization dedicated to improving the quality of investigative reporting.
White River Valley Electric
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The White River Valley Electric’s aim is straightforward: to ensure that members have safe and dependable electric service in their homes.
Kansas City Credit Union
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Kansas City Credit Union is a non-profit member-owned financial institution offering financial services.
Missouri Delta Medical Center
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Missouri Delta Medical Center provides behavioral health, cancer care, cardiology, diagnostic imaging and cardiac rehabilitation services.