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101 Top Minnesota Medical Companies and Startups of 2021 - Best Startup US

101 Top Minnesota Medical Companies and Startups of 2021

July 5, 2021
Top Companies (Navigation) show

This article showcases our top picks for the best Minnesota based Medical companies. These startups and companies are taking a variety of approaches to innovating the Medical industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Minnesota Medical Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

Crunchbase Website Twitter Facebook Linkedin

Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Mayo Clinic

Mayo Clinic

Crunchbase Website Twitter Facebook Linkedin

MayoClinic is a nonprofit medical practice and medical research group focused on integrated health care, education, and research.

Mayo Clinic

Miromatrix Medical

Crunchbase Website Twitter Facebook Linkedin

Miromatrix Medical is engaged in the development of fully biological human organs and organ-derived biological products.

Mayo Clinic

CVRx

Crunchbase Website Twitter Facebook Linkedin

CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.

Mayo Clinic

Inspire Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

Mayo Clinic

Predictive Oncology

Crunchbase Website Twitter Facebook Linkedin

Predictive Oncology is working with the pharmaceutical, diagnostic, and biotech industries to develop customizable assessment methods.

Mayo Clinic

ABILITY Network

Crunchbase Website Twitter Facebook Linkedin

ABILITY Network offers CMS-approved, secure Medicare and all-payer online access for claims processing and reimbursement.

Mayo Clinic

Zipnosis

Crunchbase Website Twitter Facebook Linkedin

Zipnosis is a hospital and healthcare company that specializes in online diagnosis and triage, telehealth, and virtual care.

Mayo Clinic

HistoSonics

Crunchbase Website Twitter Facebook Linkedin

HistoSonics specializes in developing medical devices, interventional radiology, and surgical robotics.

Mayo Clinic

Vireo Health

Crunchbase Website Twitter Facebook Linkedin

Vireo Health is a physician-led company dedicated to providing patients with best-in-class cannabis-based products and high quality care

Mayo Clinic

Monteris Medical

Crunchbase Website Twitter Facebook Linkedin

Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

Mayo Clinic

MIVI Neuroscience

Crunchbase Website Twitter Facebook Linkedin

MIVI Neuroscience focuses on developing and commercializing clinical solutions for neurointerventional procedures.

Mayo Clinic

Relievant Medsystems

Crunchbase Website Twitter Facebook Linkedin

Relievant provides patients with low risk therapy that affords the ability to alleviate their back pain.

Mayo Clinic

Nuvaira

Crunchbase Website Twitter Facebook Linkedin

Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases.

Mayo Clinic

Recombinetics

Crunchbase Website Twitter Facebook Linkedin

Recombinetics targets biomedical and regenerative medicine, opening vast new opportunities to improve and extend human life.

Mayo Clinic

Respicardia

Crunchbase Website Twitter Facebook Linkedin

Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

Mayo Clinic

HealthPartners

Crunchbase Website Twitter Facebook Linkedin

HealthPartners is a nonprofit health care provider and health insurance company providing health care services and health plan financing.

Mayo Clinic

UnitedHealth Group

Crunchbase Website Twitter Facebook Linkedin

UnitedHealth Group is a healthcare company that offers insurance products and services for everyone.

Mayo Clinic

EnteroMedics

Crunchbase Website Twitter Facebook Linkedin

EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Mayo Clinic

Conventus Orthopaedics

Crunchbase Website Twitter Facebook Linkedin

Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

Mayo Clinic

StemoniX

Crunchbase Website Twitter Facebook Linkedin

StemoniX is a biotechnology company that focuses on stem cell technologies to meet the demands of drug discovery and personalized medicine.

Mayo Clinic

NeoChord

Crunchbase Website Twitter Facebook Linkedin

NeoChord is a medical device company that develops devices that allow mitral valve repair to be performed on a beating heart.

Mayo Clinic

NovuHealth

Crunchbase Website Twitter Facebook Linkedin

NovuHealth is the leading healthcare consumer engagement company.

Mayo Clinic

4C Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

4C Medical Technologies is a medical device company that develops minimally invasive therapies for structural heart disease.

Mayo Clinic

Ativa Medical

Crunchbase Website Twitter Facebook Linkedin

Ativa Medical is working to make diagnostic test results available in moments, rather than hours and days.

Mayo Clinic

Aria CV

Crunchbase Website Twitter Facebook Linkedin

Aria CV is developing a medical device designed to improve the lives of patients living with the disease of pulmonary hypertension.

Mayo Clinic

Antares Pharma

Crunchbase Website Twitter Facebook Linkedin

Antares Pharma is a revenue-generating product focused specialty pharmaceutical company

Mayo Clinic

Lifesprk

Crunchbase Website Twitter Facebook Linkedin

Lifesprk is a hospital & health care company that offers home care management and senior living services.

Mayo Clinic

Biothera

Crunchbase Website Twitter Facebook Linkedin

Biothera is a biotechnology company developing natural gluco polysaccharides that engage and direct natural innate immune systems.

Mayo Clinic

Humanetics Corporation

Crunchbase Website Twitter Facebook Linkedin

clinical stage pharmaceutical company.

Mayo Clinic

NxThera

Crunchbase Website Twitter Facebook Linkedin

NxThera develops medical technologies to treat a variety of endourology conditions, including BPH.

Mayo Clinic

Cardiovascular Systems

Crunchbase Website Twitter Facebook Linkedin

Cardiovascular Systems develops and markets medical devices for the treatment of cardiovascular disease.

Mayo Clinic

Ambient Clinical Analytics

Crunchbase Website Twitter Facebook Linkedin

Ambient Clinical Analytics is a provider of clinical analytics solutions to health systems and hospitals,

Mayo Clinic

Entellus Medical

Crunchbase Website Twitter Facebook Linkedin

Entellus Medical develops technology-based treatment solutions for ENT physicians, their patients and payers.

Mayo Clinic

CHF Solutions

Crunchbase Website Twitter Facebook Linkedin

CHF Solutions is a medical device company that focuses on innovative cardiac assist therapy to treat patients.

Mayo Clinic

Pops Diabetes Care

Crunchbase Website Twitter Facebook Linkedin

Pops Diabetes Care offers a virtual healthcare platform to enable people to self-manage diabetes through consumer-centric sensors.

Mayo Clinic

RedBrick Health

Crunchbase Website Twitter Facebook Linkedin

RedBrick Health, a health engagement and behavior-based technology company, helps organizations optimize their health and wellness programs.

Mayo Clinic

Abilitech Medical

Crunchbase Website Twitter Facebook Linkedin

Abilitech Medical is a medical device company providing solutions for patients with neuromuscular conditions.

Mayo Clinic

Minnetronix

Crunchbase Website Twitter Facebook Linkedin

We are a medical technology and innovation company with deep expertise in electronic and electromechanical devices.

Mayo Clinic

Healthsense

Crunchbase Website Twitter Facebook Linkedin

Healthsense is a provider of aging services technology, offering technology-enabled care solutions for the senior care continuum.

Mayo Clinic

ABS

Crunchbase Website Twitter Facebook Linkedin

ABS designs and develops minimally-invasive technology that focuses on relieving pain in the knee.

Mayo Clinic

Urotronic

Crunchbase Website Twitter Facebook Linkedin

A Minnesota based, medical device company, making an exciting innovation in urethral stricture treatment.

Mayo Clinic

ShiraTronics

Crunchbase Website Twitter Facebook Linkedin

ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headache.

Mayo Clinic

Tactile Medical

Crunchbase Website Twitter Facebook Linkedin

Tactile Medical develops medical devices that support the treatment of edema and vascular diseases at home.

Mayo Clinic

IMRIS Inc.

Crunchbase Website Twitter Facebook Linkedin

IMRIS provides an image-guided therapy environment, facilitating timely information to clinicians to use during surgical procedures.

Mayo Clinic

Neuroone Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

NeuroOne is a medical technology company focused on improving surgical care for patients suffering from neurological disorders.

Mayo Clinic

Osprey Medical

Crunchbase Website Twitter Facebook Linkedin

Osprey Medical develops and commercializes its propriety CINCOR™ System designed for the prevention of contrast induced mephropathy.

Mayo Clinic

Cardionomic

Crunchbase Website Twitter Facebook Linkedin

Cardionomic is a medical device developer that treats reduced cardiac output.

Mayo Clinic

GeneMatters

Crunchbase Website Twitter Facebook Linkedin

GeneMatters delivers genetic counseling services for hospitals, health networks, academic research centers, and genetic testing labs.

Mayo Clinic

Rotation Medical

Crunchbase Website Twitter Facebook Linkedin

Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.

Mayo Clinic

Spineology

Crunchbase Website Twitter Facebook Linkedin

Spineology provides anatomy-conserving spine surgery technology solutions.

Mayo Clinic

Imbio

Crunchbase Website Twitter Facebook Linkedin

Imbio develops medical imaging software solutions that save lives and reduce costs.

Mayo Clinic

Torax Medical

Crunchbase Website Twitter Facebook Linkedin

Torax Medical develops an implantable device for the treatment of gastroesophageal reflux disease.

Mayo Clinic

Cogentix Medical

Crunchbase Website Twitter Facebook Linkedin

Cogentix Medical products have increased treatment efficiency and lowered patient risk.

Mayo Clinic

Zyga Technology

Crunchbase Website Twitter Facebook Linkedin

Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems.

Mayo Clinic

Venture Med Group

Crunchbase Website Twitter Facebook Linkedin

VMG designs, develops which enable interventionalists to cost effectively treat peripheral artery diseases.

Mayo Clinic

ValenTx

Crunchbase Website Twitter Facebook Linkedin

ValenTx is a development-stage medical device company that focuses on minimally-invasive methods for the treatment of morbid obesity.

Mayo Clinic

Cryosa

Crunchbase Website Twitter Facebook Linkedin

CryOSA is a medical device company developing novel treatments for obstructive sleep apnea.

Mayo Clinic

Francis Medical

Crunchbase Website Twitter Facebook Linkedin

Francis Medical is a Medical Technology Company.

Mayo Clinic

Reprise Biomedical

Crunchbase Website Twitter Facebook Linkedin

Reprise Biomedical focuses on the development and commercialization of biological medical devices.

Mayo Clinic

SynerFuse

Crunchbase Website Twitter Facebook Linkedin

SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

Mayo Clinic

Murata Vios

Crunchbase Website Twitter Facebook Linkedin

Murata Vios is a medical technology company developing wireless monitoring platform for intensive healthcare applications.

Mayo Clinic

CardiaLen

Crunchbase Website Twitter Facebook Linkedin

CardiaLen develops and commercializes pain-free cardioversion therapies for atrial fibrillation.

Mayo Clinic

Mardil Medical

Crunchbase Website Twitter Facebook Linkedin

Mardil Medical is a medical device company developing therapies for structural heart diseases and heart abnormalities.

Mayo Clinic

Interrad Medical

Crunchbase Website Twitter Facebook Linkedin

Interrad Medical develops innovative medical devices for use in minimally invasive interventional and surgical procedures.

Mayo Clinic

MicroOptx

Crunchbase Website Twitter Facebook Linkedin

MicroOptx is an early-stage medical device company that leverages academic bioengineering.

Mayo Clinic

Optum

Crunchbase Website Twitter Facebook Linkedin

OptumInsight provides analytics, technology, and consulting services to improve the performance of health systems.

Mayo Clinic

Preceptis Medical

Crunchbase Website Twitter Facebook Linkedin

Preceptis Medical develops surgical tools that allow ear tube procedures to be performed with less pain.

Mayo Clinic

Cardio Flow

Crunchbase Website Twitter Facebook Linkedin

Cardio Flow is an early-stage development company with a new approach to orbital atherectomy.

Mayo Clinic

Tendyne Holdings

Crunchbase Website Twitter Facebook Linkedin

Tendyne is a medical device company developing a transcatheter aortic valve implantation system.

Mayo Clinic

Elucent Medical

Crunchbase Website Twitter Facebook Linkedin

Elucent Medical is a new idea in breast cancer treatment that exists to bring better healthcare ideas.

Mayo Clinic

Leafline Labs

Crunchbase Website Twitter Facebook Linkedin

LeafLine Labs provides high quality medical cannabis and care to patients.

Mayo Clinic

Vergent Bioscience

Crunchbase Website Twitter Facebook Linkedin

Vergent Bioscience is a biotech company leading the development of tumor-targeted molecular imaging molecules for cancer surgery.

Mayo Clinic

AUM Cardiovascular

Crunchbase Website Twitter Facebook Linkedin

AUM Cardiovascular is a medical device manufacturing company that specializes in the fields of biotechnology, medical, and healthcare.

Mayo Clinic

Skyline Medical Inc.

Crunchbase Website Twitter Facebook Linkedin

BioDrain Medical offers STREAMWAY System, a surgical fluid disposal device that eliminates exposure to blood and infectious fluids.

Mayo Clinic

Vertebral Technologies

Crunchbase Website Twitter Facebook Linkedin

Vertebral Technologies is a medical device company that creates breakthrough implantable spinal devices.

Mayo Clinic

SpineThera

Crunchbase Website Twitter Facebook Linkedin

SpineThera develops novel, sustained-release, injectable drugs to treat pain.

Mayo Clinic

ExceleraRx

Crunchbase Website Twitter Facebook Linkedin

Excelera is a specialty pharmacy network helping members assert control over complex patient outcomes and total cost of care.

Mayo Clinic

EmStop

Crunchbase Website Twitter Facebook Linkedin

EmStop engages in the medical devices business namely embolic protection devices.

Mayo Clinic

Thaddeus Medical

Crunchbase Website Twitter Facebook Linkedin

Connected hardware to control and track temperature for sensitive medical products.

Mayo Clinic

Surgical Information Sciences

Crunchbase Website Twitter Facebook Linkedin

Surgical Information Sciences is a healthcare Company.

Mayo Clinic

Augustine Temperature Management

Crunchbase Website Twitter Facebook Linkedin

Augustine Temperature Management develops conductive fabric patient warming systems for surgical patients in the United States.

Mayo Clinic

CoraVie Medical Inc.

Crunchbase Website Twitter Facebook Linkedin

Early stage med device co. developing a subcutaneous continuous blood pressure monitor for patients with uncontrolled hypertension.

Mayo Clinic

Stimdia Medical

Crunchbase Website Twitter Facebook Linkedin

Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

Mayo Clinic

Nirva Medical

Crunchbase Website Twitter Facebook Linkedin

Nirva Medical is a medical device start up focusing on organ-specific therapy-delivery technology for various clinical applications.

Mayo Clinic

Minnesota Medical Solutions

Crunchbase Website Twitter Facebook Linkedin

Minnesota Medical Solutions is one of only two licensed medical cannabis manufacturers .

Mayo Clinic

MetaModix

Crunchbase Website Twitter Facebook Linkedin

MetaModix manufactures surgical and medical instruments for the treatment of metabolic disease and Type II diabetes.

Mayo Clinic

Univita Health

Crunchbase Website Twitter Facebook Linkedin

Univita Health provides home-based care management programs to improve patient outcomes and lower health care costs.

Mayo Clinic

Celleration

Crunchbase Website Twitter Facebook Linkedin

Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

Mayo Clinic

RoverMed BioSciences

Crunchbase Website Twitter Facebook Linkedin

RoverMed has developed precision targeted nanocapsule technology aimed at delivering life saving drugs to the most challenging disease sites

Mayo Clinic

Cardia

Crunchbase Website Twitter Facebook Linkedin

Cardia is an innovative company engaged in developing, manufacturing and marketing transcatheter septal occluders.

Mayo Clinic

NitriCap Medical

Crunchbase Website Twitter Facebook Linkedin

NitriCap Medical develops a single-use antimicrobial catheter insert device to fight catheter-related bloodstream infections.

Mayo Clinic

Autonomix Medical

Crunchbase Website Twitter Facebook Linkedin

Autonomix Medical is a developer of a novel technology designed to bring clarity to minimally invasive renal denervation.

Mayo Clinic

Ocudyne

Crunchbase Website Twitter Facebook Linkedin

Ocudyne is based in Baltimore, Maryland.

Mayo Clinic

Alska

Crunchbase Website Twitter Facebook Linkedin

Alska provides family caregivers with the ability to store, manage and share key information.

Mayo Clinic

Marblehead Medical

Crunchbase Website Twitter Facebook Linkedin

Marblehead Medical is a developer of device intended to optimize the efficacy of mechanical thrombectomy.

Mayo Clinic

Novidan

Crunchbase Website Twitter Facebook Linkedin

Novidan is designs, engineers and source products for the hard of hearing patient.

Mayo Clinic

SuperDimension

Crunchbase Website Twitter Facebook Linkedin

SuperDimension is a medical device company developing minimally invasive pulmonology devices for the treatment of distal lung disease.

Mayo Clinic

St. Jude Medical

Crunchbase Website Twitter Facebook Linkedin

St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac,

Mayo Clinic

Phraxis

Crunchbase Website Twitter Facebook Linkedin

Phraxis is a medical device company developing solutions for patients who need vascular access to enable hemodialysis.

Mayo Clinic

Advanced Circulatory System

Crunchbase Website Twitter Facebook Linkedin

Advanced Circulatory System manufactures and markets intrathoracic pressure regulation products.

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