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101 Top San Francisco Software Companies and Startups of 2021

This article showcases our top picks for the best San Francisco based Software companies. These startups and companies are taking a variety of approaches to innovating the Software industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top San Francisco Software Startups

Data sourced from Crunchbase and SemRush.

Plaid

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Plaid provides companies with the tools and access needed for the development of a digitally-enabled financial system.

Cruise

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Cruise builds self-driving vehicles that safely connect people to places, things, and experiences they care about.

DocuSign

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DocuSign helps small- and medium-sized businesses collect information, automate data workflows, and sign on various devices.

WalkMe

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WalkMe’s digital adoption platform enables organizations to measure, drive, and act to maximize the impact of their digital transformation.

GitLab

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GitLab is a web-based open source Git repository manager with wiki and issue tracking features and built-in CI/CD.

Fastly

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Fastly helps digital businesses keep pace with their customer expectations by delivering secure and online experiences.

Fireflies.ai

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Fireflies.ai offers an AI Meeting assistant that records, transcribes, and makes searchable meeting notes.

Iterable

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Iterable provides a marketing automation platform designed to optimize and measure every customer interaction.

Pinterest

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Pinterest is a visual bookmarking tool for saving and discovering creative ideas.

Shippo

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Shippo is a shipping platform that helps e-commerce companies manage their shipping operations more seamlessly.

Skillz

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Skillz is a marketplace platform for competition-based mobile games.

Razer

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Razer develops high-end precision gaming products by combining technology, ergonomics, and expert validation.

Docker

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Docker provides an open platform for building, shipping, and running distributed applications.

Carta

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Carta is building a global ownership management platform to help companies, investors, and employees manage their equity.

GitHub

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GitHub provides code hosting services that allow developers/people to build software for open source and private projects in organizations.

Bitwise

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Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Pipefy

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Pipefy specializes in the fields of process management, workflow, process automation, and task management.

Okta

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Okta is a management platform that secures critical resources from cloud to ground for workforce and customers.

Cloudflare

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Cloudflare is a web performance and security company that provides online services to protect and accelerate websites online.

Dropbox

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Dropbox is a smart workspace company that provides secure file sharing, collaboration, and storage solutions.

Datavant

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Datavant is a provider of a healthcare data solutions to help institutions share, protect, and match health data.

HashiCorp

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HashiCorp is a remote-first company that solves development, security, and operations challenges in infrastructure.

SpotOn

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SpotOn develops innovative software and payment solutions that help businesses increase revenue.

Aurora Solar

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Aurora Solar is a SaaS company that uses aerial imagery to assess solar installation projects.

Niantic

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Niantic builds augmented reality platform for current and future generations of AR hardware.

Snapdocs

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Snapdocs is a mortgage technology company that helps real estate participants closing work together through integration and automation.

Coda

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Coda is a new document that brings words, data, and teams together.

Embroker

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Embroker helps growing businesses save time and find the best value on the right coverage.

Contentstack

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Contentstack develops a cloud based content management system intended to power omnichannel content.

Dialpad

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Dialpad is an AI-powered cloud communications platform that turns conversations into opportunities and helps teams make smart calls.

Aclima

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Putting air pollution and greenhouse gases on the map, block by block, to reduce emissions, improve public health and advance equity.

Lattice

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Lattice is a people management platform that empowers people leaders to build engaged, high-performing teams.

Vanta

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Vanta is an automated security monitoring platform that helps companies get SOC 2, HIPAA, or ISO 27001 certified quickly.

Twilio

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Twilio is a cloud communication company that enables users to use standard web languages to build voice, VoIP, and SMS apps via a web API.

Gigster

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Gigster is the first team intelligence engine, enabling software development teams to achieve 30% higher efficiency.

Chargebee

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Chargebee provides subscription and recurring billing systems for SaaS and e-commerce businesses.

Samsara

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Samsara is the pioneer of the Connected Operations Cloud

Sitecore

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Sitecore is a customer experience management company that provides multichannel marketing automation software and web content management.

PagerDuty

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PagerDuty is an operations performance platform delivering visibility and actionable intelligence across the entire incident lifecycle.

Algolia

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Algolia is the Search-as-a-Service platform that enables companies to deliver fast and relevant digital experiences that drive real results.

People.ai

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People is an AI platform for enterprise sales, marketing, and customer success that uncovers every revenue opportunity from every customer.

App Annie

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App Annie is a mobile data and analytics platformthat delivers data and insights to succeed in the app economy.

Chorus.ai

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Chorus.ai is an AI conversation intelligence cloud platform for sales team that can transform conversations into data and insights.

MURAL

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MURAL is a digital workspace for visual collaboration

Grand Rounds Health

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Grand Rounds Health is a tech-driven healthcare company that offers an employer-based technology alternative for healthcare services.

CircleCI

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CircleCI is a continuous integration and delivery platform that automates development workflows and IT operations.

Discord

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Discord is an online voice, video and text service designed for hanging out with friends and creating communities around shared interests.

Verily

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Verily develops tools and devices to collect and analyze health data to research and manage diseases.

Heap

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Heap is a platform that provides analytics infrastructure to reduce the annoying parts of user analytics.

New Relic

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New Relic is a digital intelligence company that delivers full-stack visibility and analytics to enterprises.

Copper

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Copper offers customer relationship management solutions for companies that use Google applications.

RudderStack

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RudderStack is the CDP for developers.

Medallia

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Medallia offers a SaaS platform that captures experience data from signal fields emitted by customers and employees.

[redacted]

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Redacted is a cybersecurity provider that disrupts customer’s adversaries and protect their businesses.

Census

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Census is a data automation platform that synchronizes customer’s data warehouses with business systems and tools.

Ironclad

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Ironclad is one of the nation’s top makers of enterprise software for managing contracts

PostHog

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PostHog provides a platform for open-source product analytics to helps software teams understand user behavior.

Grammarly

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Grammarly’s digital writing assistant helps people write more clearly and effectively.

MindTickle

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MindTickle is a software company that offers sales readiness and enablement tools for businesses.

Planet

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Planet is an aerospace and data analytics company that builds small satellites and delivers information about the changing planet.

ForgeRock

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ForgeRock is a multinational software company that develops commercial open source identity and access management products.

Bright Machines

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Bright Machines brings together flexible factory robots with intelligent software, production data and machine learning.

Forethought

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Forethought builds artificially intelligent agents to supercharge enterprise workflows, starting with Agatha, the AI for Customer Support.

Doximity

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Doximity is the leading digital platform for medical professionals

Intercom

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Conversational Relationship Platform helping businesses build customer relationships through personalized, messenger-based experiences.

Expensify

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Expensify is a financial services startup that provides an integrated expense management and corporate card product for customers worldwide.

Benchling

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Benchling is a cloud-based software platform for biology researchers and research and development organizations.

HomeLight

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HomeLight is building the future of real estate — today.

Aura Financial

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Aura is a financial service company that provides affordable, credit-building loans to working families.

Qualio

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Qualio is a quality management system helping life sciences companies bring quality products to the market.

Notion

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Notion is the all-in-one workspace for your notes, tasks, wikis, and databases

Anaplan

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Anaplan provides a connected planning platform that helps businesses make better-informed plans and decisions faster.

Crate.io

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Crate.io develops CrateDB, purpose-built to scale applications in a machine data world.

Curebase

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Curebase is a provider of decentralized clinical research software solutions and services to patients and medical providers.

Fundbox

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Fundbox is an AI-powered financial platform for small businesses.

Honeycomb

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The fastest way to visualize, understand and debug software. Find the critical issues that logs and metrics can’t see.

MuleSoft

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MuleSoft provides an integration and API platform that makes it easy to connect data from any system to create connected experiences.

Zendesk

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Zendesk is a customer service platform that develops a software to empower organization and customer relationships.

Komodo Health

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Komodo Health develops computer software that brings transparency and market intelligence to healthcare and life sciences.

Vim

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Vim is a technology company building digital infrastructure for healthcare.

Sentry

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Sentry is a developer of an application monitoring platform that helps developers monitor apps in real time to catch bugs early.

Hive

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Hive provides cloud-based enterprise AI solutions designed for intelligent automation.

MemSQL

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SingleStore is a provider of a database for operational analytics and cloud-native applications.

MaintainX

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MaintainX is a mobile-first workflow management platform that allows factory frontline teams to know what they need to do and how to do it.

Observe.AI

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Observe.AI is a software company that leverages AI, Natural Language Processing, and analytics to develop contact center software.

Prismic

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Headless CMS with an API, CDN and a Writing Room

Checkr

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Checkr seeks to automate the process of professional background checks.

SightCall

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SightCall is a live video SaaS enabling visual support for enterprises enriched by Augmented Reality and Artificial Intelligence insights.

Domino Data Lab

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Unleash the power of data science to address the world’s most important challenges.

Specto

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Specto is a mobile application performance monitoring platform that collects vital metrics and profiles with just a few lines of code.

Affinity

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Affinity is a relationship intelligence platform built to expand and evolve the traditional CRM.

Pilot

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Pilot is a platform that offers bookkeeping, tax, and CFO services for growing businesses.

OODA Health

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OODA Health is a healthcare technology company that offers a software billing platform for providers, payers, patients, and insurers.

Vercel

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Vercel is a platform that enables users to develop, preview, and ship Jamstack sites.

Sentieo

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Sentieo is a research platform that provides insights within the finance and corporate world.

Rewatch

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Rewatch offers a private and secure video channel for teams.

Pantheon

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Pantheon is the WebOps platform where marketers, designers and developers drive results with WordPress and Drupal websites.

Amplitude

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Amplitude is a product intelligence platform that provides digital product tools that help teams run and grow their businesses.

Standard Cognition

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Standard Cognition provides an autonomous checkout tool that can be installed into retailers’ existing stores.

Journal

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Journal is a place to visually organize content from every app and website.

UpGuard

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UpGuard is a cyber resilience platform, designed to proactively assess and manage the business risks posed by technology.

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