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101 Top New York City Biotechnology Companies and Startups of 2021

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This article showcases our top picks for the best New York City based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top New York City Biotechnology Startups

Data sourced from Crunchbase and SemRush.

H1

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H1 provides the largest global healthcare platform to help life sciences companies, hospitals, academic medical centers, and health systems.

Bristol-Myers Squibb

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Bristol-Myers Squibb engages in the discovery, development, licensing, manufacturing, marketing, distribution, and sale of pharmaceuticals.

Pfizer

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Pfizer provides access to safe and effective and affordable medicines and health care services.

TMRW Life Sciences

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TMRW Life Sciences provides an integrated platform for automated, software-guided cryospecimen management.

Flatiron Health

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Flatiron Health is a healthcare technology company that aims to improve lives by learning from the experience of every cancer patient.

Click Therapeutics

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Click Therapeutics deliver safe and effective digital treatments to patients in need

Roivant Sciences

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Roivant Sciences is a biopharmaceutical company focused on completing the development of promising late-stage drug candidates.

Schrödinger

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Schrödinger develops a chemical simulation software for use in pharmaceutical and biotechnology research.

Enochian BioSciences

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Enochian BioSciences is focusing on the clinical development of a dendritic cell vaccine for treatment of colorectal cancer.

Big Idea Ventures

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Investing in Great Entrepreneurs Solving the World’s Biggest Challenges

Immunai

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Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.

Zentalis Pharmaceuticals

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Zentalis is a clinical-stage biopharmaceutical company focused on developing clinically differentiated, novel small molecule therapeutics.

Imagen Technologies

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Eliminating diagnostic errors in medicine

Owkin

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Owkin is a startup that provides machine learning that allows medical researchers to test AI models on distributed data.

Elevation Oncology

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Elevation Oncology is a clinical-stage biopharmaceutical company focused on the development of precision medicines for patients.

HiberCell

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HiberCell is a biotechnology company developing treatments to prevent cancer relapse and metastasis.

LEXEO Therapeutics

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LEXEO Therapeutics is a biotechnology company.

Brooklyn ImmunoTherapeutics

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Brooklyn ImmunoTherapeutics is a clinical=stage biopharmaceutical company discovers and develops a novel cytokine-based therapy.

Axsome Therapeutics

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Axsome Therapeutics develops and commercializes therapies for the management and treatment of pain and other neurological disorders.

FORMULA

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FORMULA is a personalized nootropics company that offers nootropic supplements for peoples’ unique needs.

COTA Healthcare

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Bringing clarity to cancer. Working to ensure that everyone touched by cancer has a clear path to the right care.

Nutrafol

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Nutrafol is a nutraceutical manufacturer that formulates all-natural, drug-free products to improve hair growth.

Theseus Pharmaceuticals

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Theseus Pharmaceuticals is a technology-based company.

Iovance Biotherapeutics

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Iovance Biotherapeutics develops T-cell-based immunotherapy products for the treatment of cancer.

Anavex

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Anavex is a biopharmaceutical company developing drugs for the treatment of cancer and neurological diseases.

Stablix

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Stablix Therapeutics is a biotechnology company pioneering the field of Targeted Protein Stabilization (TPS).

Synergy Pharmaceuticals

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Synergy Pharmaceuticals is a biopharmaceutical company developing novel therapies for the treatment of gastrointestinal conditions.

Kallyope

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Kallyope is a healthcare company focusing on biotechnology business.

Tonix Pharmaceuticals Holding

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Tonix Pharmaceuticals Holding develops pharmaceutical products for central nervous system disorders.

Abeona Therapeutics

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Abeona Therapeutics develops gene therapy-based potential cures for Sanfilippo syndrome types A and B.

Nuvation Bio

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Nuvation Bio is a biopharmaceutical company.

Everest Medicines

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Everest Medicines is dedicated to its mission of developing and commercializing novel transformative pharmaceutical therapies for patients.

TG Therapeutics

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TG Therapeutics, a biopharmaceutical company, develops agents for the treatment of hematologic malignancies and autoimmune disorders.

Prevail Therapeutics

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Prevail Therapeutics is a biotechnology company focused on developing novel gene therapies for patients with Parkinson’s disease.

Kadmon

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Kadmon Corporation is a biopharmaceutical company offering products and services for the treatment and management of hepatitis C.

Redesign Science

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Redesign Science is a computational chemistry company setting a new standard for early-stage, small molecule drug discovery.

SIMULATE

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SIMULATE is an early-stage biotechnology company that accelerate the transition to sustainable nutrition.

Celmatix

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Celmatix is a preclinical-stage women’s health biotech focused uniquely on ovarian biology

Gennao Bio

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Gennao Bio is a genetic medicines company that develops targeted nucleic acid therapeutics to cure muscle diseases.

UroGen Pharma

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UroGen Pharma is a clinical-stage biopharmaceutical company.

Exosome Diagnostics

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Exosome Diagnostics develops and commercializes blood-based cancer molecular diagnostics for patient stratification and disease monitoring.

Intercept Pharmaceuticals

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Intercept Pharmaceuticals develops small molecule drugs and therapeutics for the treatment of chronic fibrotic and metabolic diseases.

Fortress Biotech

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Fortress Biotech is biopharmaceutical company focused on acquiring, developing, and commercializing drugs and drug candidates.

Gilgamesh Pharmaceuticals

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Gilgamesh Pharmaceuticals provides medicines for psychedelic, novel psychotropic drugs, depression, anxiety, and stress-related disorders.

Overture Life

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Overture Life is a biotechnology company

Ziopharm oncology

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Ziopharm oncology is a biotechnology company that acquires, develops, and commercializes cancer therapies.

Intra-Cellular Therapies

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Intra-Cellular Therapies develops drugs for the treatment of neuropsychiatric and neurologic diseases, and other disorders of the CNS.

Applied Therapeutics

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Applied Therapeutics uses drug-development approach to target molecules and pathways that has roles in fatal or debilitating diseases.

Synaptogenix

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Synaptogenix is a clinical-stage biopharmaceutical company that develops novel therapies for neurodegenerative diseases.

Ovid Therapeutics

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Ovid Therapeutic’s purpose is to solve intractable medical problems.

Phosphorus

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Phosphorus provides the back-end infrastructure that enables ubiquitous integration of genetics in medicine.

Seelos Therapeutics

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Seelos Therapeutics Inc is a clinical-stage biopharmaceutical company focused on the development and advancement of novel therapeutics.

Volastra Therapeutics

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Volastra Therapeutics is a biotechnology company developing novel therapies for the treatment of metastatic cancers.

Lodo Therapeutics

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Lodo Therapeutics is a drug discovery and development company.

IN8Bio

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IN8Bio is a biotechnology company focused on delivering a novel off-the-shelf product for the treatment of cancer.

Loxo Oncology

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Loxo Oncology is a biopharmaceutical company focused on targeted cancer therapies for genetically-defined patient populations.

Mustang Bio

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Mustang Bio is a clinical-stage biopharmaceutical company .

MindMed

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MindMed is a psychedelic biotech company developing medicines and therapies to address addiction and mental illness.

Massive Bio

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Massive Bio is an AI powered oncology platform that connects patients to clinical trials while enabling pharma to get access to patients.

Sio Gene Therapies

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Sio Gene Therapies is a clinical-stage biopharmaceutical company.

US HealthVest

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US HealthVest is a behavioral healthcare firm that helps the development of psychiatric hospitals.

Emendo Biotherapeutics

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Emendo Biotherapeutics is a biotechnology company

Neurogene

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Neurogene is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.

Rgenix

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Rgenix is a biotechnology company developing drugs for the treatment of cancer.

Scopus BioPharma

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Scopus BioPharma is a biotechnology company that focuses on developing small molecule therapeutics in cannabinoid and cannabis.

BrainStorm Cell Therapeutics

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Brainstorm is a developing innovative, autologous stem cell therapies for highly debilitating neurodegenerative disorders.

Aceto

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Aceto is a global virtual manufacturer supplying niche, differentiated specialty materials in life sciences and advanced technology.

Re-Nuble

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Re-Nuble is an agtech company that transforms unrecoverable vegetative food into a platform of sustainable technologies for soilless farming

MeiraGTx

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Meira Gene Therapy is a clinical-stage company developing novel treatments for inherited and acquired genetic disorders.

TARA Biosystems

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TARA Biosystems Harnessing Human Biology + Data to Transform Cardiac Drug Discovery

Ozette Technologies

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Ozette is a life sciences data startup company that develops an artificial intelligence-enabled immune monitoring platform.

BioVaxys

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BioVaxys is a clinical stage biotechnology company developing immunotherapeutic cancer vaccines targeting melanoma.

RenBio

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RenBio develops antibody-based therapeutic solutions for the treatment of cancer and inflammatory diseases.

Gencove

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Industrial-scale genome sequencing

Envisagenics

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Envisagenics seeks to reduce the complexity of biomedical data to accelerate the development of innovative therapeutic solutions.

Flame Biosciences

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Flame Biosciences develops value-added medicines in the emerging area of inflammasome science.

Hilma

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Hilma creates quality products and natural remedies to support health when needed it most.

AlgiKnit

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AlgiKnit is a biomaterials company integrating science and design into textile production.

Eyenovia

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Eyenovia is a biopharmaceutical company that provides a portfolio of next generation topical eye treatments.

Protara Therapeutics

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Protara Therapeutics develops transformative therapies for people with cancer and rare diseases with limited treatment options.

Clarapath

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We are a medical robotics company developing the SectionStar, a platform to mimic the human histotechnician.

SolveBio

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SolveBio deploys technology and on-demand expertise to drive precision medicine. We monitor, gather, and secure Genomic Intelligence.

Quentis Therapeutics

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Quentis Therapeutics is a developer of immuno-therapeutics designed to address ER stress in multiple diseases.

Apos Therapy

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Apos Therapy is a medical technology company providing treatment for various orthopedic conditions.

Xalud Therapeutics

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Xalud Therapeutics is a biotech company that develops therapies for the treatment of neuro-inflammatory diseases.

Hoth Therapeutics

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Hoth Therapeutics is a clinical-stage biopharmaceutical company focused on developing new generation therapies for dermatological disorders.

Allelica

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Allelica is a genomics software company driving the transition of Polygenic Risk Score from Genomic research to clinical application.

Gotham Therapeutics

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Gotham Therapeutics is discovering a novel drug class targeting the epitranscriptomics machinery.

Treadwell Therapeutics

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Treadwell Therapeutics is a clinical-stage oncology company.

OneThree Biotech

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OneThree Biotech redesigns drug discovery with biology-driven artificial intelligence.

Starton Therapeutics

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Starton Therapeutics is a biotechnology company focused on transforming standard of care therapeutics.

Actinium Pharmaceuticals

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Actinium Pharmaceuticals develops alpha particle linked antibodies to treat cancer.

Artizan Biosciences

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Artizan Biosciences focuses on drug discovery and development for diseases involving the human intestinal microbiota.

Oramed Pharmaceuticals

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Oramed Pharmaceuticals develops proprietary Protein Oral Delivery technology for the delivery of drugs.

GenePeeks

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GenePeeks is a genetic information company

Delcath Systems

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Delcath Systems and its proprietary targeted drug delivery system are at the forefront of the regional treatment of cancer.

SIGA Technologies

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At SIGA, we specialize in developing therapeutic solutions for some of the most lethal pathogens – smallpox.

Genoplan

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Genoplan helps reshape your future by utilizing cutting-edge medical technology and scientific innovation.

Redpin Therapeutics

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Redpin Therapeutics is a preclinical stage gene therapy company that develops chemogenetics platform designed for nervous system diseases.

BioDigital

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BioDigital offers BioDigital Human Platform, a tool that simplifies complex health concepts through visualization.

Nine Square Therapeutics

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Nine Square Therapeutics is a developer of novel therapies for movement disorders.

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