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101 Top Minnesota Medical Device Companies and Startups of 2021

This article showcases our top picks for the best Minnesota based Medical Device companies. These startups and companies are taking a variety of approaches to innovating the Medical Device industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top Minnesota Medical Device Startups

Data sourced from Crunchbase and SemRush.

Medtronic

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Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Miromatrix Medical

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Miromatrix Medical is engaged in the development of fully biological human organs and organ-derived biological products.

CVRx

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CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.

Inspire Medical Systems

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Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

HistoSonics

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HistoSonics specializes in developing medical devices, interventional radiology, and surgical robotics.

Monteris Medical

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Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

MIVI Neuroscience

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MIVI Neuroscience focuses on developing and commercializing clinical solutions for neurointerventional procedures.

Nuvaira

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Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases.

Respicardia

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Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

EnteroMedics

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EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Conventus Orthopaedics

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Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

NeoChord

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NeoChord is a medical device company that develops devices that allow mitral valve repair to be performed on a beating heart.

4C Medical Technologies

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4C Medical Technologies is a medical device company that develops minimally invasive therapies for structural heart disease.

Aria CV

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Aria CV is developing a medical device designed to improve the lives of patients living with the disease of pulmonary hypertension.

Biothera

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Biothera is a biotechnology company developing natural gluco polysaccharides that engage and direct natural innate immune systems.

NxThera

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NxThera develops medical technologies to treat a variety of endourology conditions, including BPH.

Cardiovascular Systems

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Cardiovascular Systems develops and markets medical devices for the treatment of cardiovascular disease.

Entellus Medical

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Entellus Medical develops technology-based treatment solutions for ENT physicians, their patients and payers.

Pops Diabetes Care

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Pops Diabetes Care offers a virtual healthcare platform to enable people to self-manage diabetes through consumer-centric sensors.

Abilitech Medical

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Abilitech Medical is a medical device company providing solutions for patients with neuromuscular conditions.

Minnetronix

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We are a medical technology and innovation company with deep expertise in electronic and electromechanical devices.

Healthsense

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Healthsense is a provider of aging services technology, offering technology-enabled care solutions for the senior care continuum.

ABS

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ABS designs and develops minimally-invasive technology that focuses on relieving pain in the knee.

Urotronic

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A Minnesota based, medical device company, making an exciting innovation in urethral stricture treatment.

ShiraTronics

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ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headache.

Tactile Medical

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Tactile Medical develops medical devices that support the treatment of edema and vascular diseases at home.

IMRIS Inc.

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IMRIS provides an image-guided therapy environment, facilitating timely information to clinicians to use during surgical procedures.

Osprey Medical

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Osprey Medical develops and commercializes its propriety CINCOR™ System designed for the prevention of contrast induced mephropathy.

Cardionomic

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Cardionomic is a medical device developer that treats reduced cardiac output.

Rotation Medical

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Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.

Spineology

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Spineology provides anatomy-conserving spine surgery technology solutions.

Imbio

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Imbio develops medical imaging software solutions that save lives and reduce costs.

Torax Medical

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Torax Medical develops an implantable device for the treatment of gastroesophageal reflux disease.

Cogentix Medical

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Cogentix Medical products have increased treatment efficiency and lowered patient risk.

Zyga Technology

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Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems.

Venture Med Group

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VMG designs, develops which enable interventionalists to cost effectively treat peripheral artery diseases.

ValenTx

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ValenTx is a development-stage medical device company that focuses on minimally-invasive methods for the treatment of morbid obesity.

Cryosa

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CryOSA is a medical device company developing novel treatments for obstructive sleep apnea.

Reprise Biomedical

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Reprise Biomedical focuses on the development and commercialization of biological medical devices.

SynerFuse

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SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

Murata Vios

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Murata Vios is a medical technology company developing wireless monitoring platform for intensive healthcare applications.

CardiaLen

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CardiaLen develops and commercializes pain-free cardioversion therapies for atrial fibrillation.

Mardil Medical

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Mardil Medical is a medical device company developing therapies for structural heart diseases and heart abnormalities.

Interrad Medical

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Interrad Medical develops innovative medical devices for use in minimally invasive interventional and surgical procedures.

Preceptis Medical

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Preceptis Medical develops surgical tools that allow ear tube procedures to be performed with less pain.

Cardio Flow

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Cardio Flow is an early-stage development company with a new approach to orbital atherectomy.

Tendyne Holdings

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Tendyne is a medical device company developing a transcatheter aortic valve implantation system.

Vergent Bioscience

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Vergent Bioscience is a biotech company leading the development of tumor-targeted molecular imaging molecules for cancer surgery.

AUM Cardiovascular

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AUM Cardiovascular is a medical device manufacturing company that specializes in the fields of biotechnology, medical, and healthcare.

Skyline Medical Inc.

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BioDrain Medical offers STREAMWAY System, a surgical fluid disposal device that eliminates exposure to blood and infectious fluids.

Vertebral Technologies

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Vertebral Technologies is a medical device company that creates breakthrough implantable spinal devices.

EmStop

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EmStop engages in the medical devices business namely embolic protection devices.

Surgical Information Sciences

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Surgical Information Sciences is a healthcare Company.

Augustine Temperature Management

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Augustine Temperature Management develops conductive fabric patient warming systems for surgical patients in the United States.

CoraVie Medical Inc.

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Early stage med device co. developing a subcutaneous continuous blood pressure monitor for patients with uncontrolled hypertension.

Stimdia Medical

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Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

Nirva Medical

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Nirva Medical is a medical device start up focusing on organ-specific therapy-delivery technology for various clinical applications.

MetaModix

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MetaModix manufactures surgical and medical instruments for the treatment of metabolic disease and Type II diabetes.

Celleration

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Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

Cardia

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Cardia is an innovative company engaged in developing, manufacturing and marketing transcatheter septal occluders.

NitriCap Medical

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NitriCap Medical develops a single-use antimicrobial catheter insert device to fight catheter-related bloodstream infections.

Autonomix Medical

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Autonomix Medical is a developer of a novel technology designed to bring clarity to minimally invasive renal denervation.

Marblehead Medical

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Marblehead Medical is a developer of device intended to optimize the efficacy of mechanical thrombectomy.

Novidan

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Novidan is designs, engineers and source products for the hard of hearing patient.

SuperDimension

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SuperDimension is a medical device company developing minimally invasive pulmonology devices for the treatment of distal lung disease.

St. Jude Medical

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St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac,

Phraxis

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Phraxis is a medical device company developing solutions for patients who need vascular access to enable hemodialysis.

Advanced Circulatory System

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Advanced Circulatory System manufactures and markets intrathoracic pressure regulation products.

B-MoGen Biotechnologies

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B-MoGen Biotechnologies is a genome engineering startup out of Minneapolis, MN.

EmboMedics

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EmboMedics develops and commercializes resorbable and drug-loaded embolization devices for the treatment of multiple indications.

Radux Devices

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Radux Devices develops medical devices that improve the procedural performance of physicians, healthcare professionals, and hospitals.

Pursuit Vascular

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Pursuit Vascular is focused on developing innovative catheter infection reduction technologies.

Chitogen

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Chitogen is a medical device company designing, manufacturing, and selling topical hemostats and related wound care products.

Uromedica

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Uromedica is a medical device company developing an adjustable balloon device for stress urinary incontinence (SUI).

Caisson Interventional

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Caisson Interventional is a privately held clinical-stage medical device company focused on the design.

Peytant Solutions

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Peytant Solutions is a regenerative medical device company.

RespirTech

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RespirTech dedicated to improving the quality of life for those living with respiratory complications.

Sterilucent

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Sterilucent is a health care company that develops and markets vaporized (gas) hydrogen peroxide technology.

SubioMed

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SubioMed specializes in the invention and development of suspension biomechanics technology addressing gait and balance.

Egg Medical

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Egg Medical is a medical device company that offers EGGNEST, a passive protection designed to drastically reduce scatter radiation exposure.

Zurich Medical

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Zurich Medical develops proprietary medical devices.

AdrenaCard

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AdrenaCard is a pharmaceutical company that combines proven, life-saving drugs with devices that make them easier to carry.

OrthoCor Medical

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OrthoCor Medical develops and delivers medical devices for joint pain.

GT Urological

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GT Urological, LLC develops, manufactures, distributes, and markets medical devices for the urinary incontinence market.

Levity Products

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Levity Products is provides health care services.

Boston Scientific Scimed

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Boston Scientific Scimed is develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.

UroCure

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UroCure is a healthcare company that re-commercializes slings for female incontinence with IP re-acquired from AMS.

Tiumed, LLC

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Tiumed’s next-generation plasma technology platform addresses the critical gap in BPH surgery with improved effectiveness and efficiency.

NovoPulse

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NovoPulse is a thermally assisted electrical stimulation device designed for pain management and treatment of osteoarthritis.

Exostat Medical

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Exostat Medical develops MicroStat Systems, a systemic monitoring device to measure carbon dioxide in the oral mucosa.

Wound Care Technologies

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Wound Care Technologies, a medical technology company, develops and markets external tissue expansion devices for the wound care market.

Medafor

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Medafor develops novel hemostatic technology and absorbable hemostats called MPH(R), which accelerates the normal blood clotting process.

MFr Technologies

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MFr Technologies is a health care company.

Dgimed Ortho

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DGIMed Ortho is an early-stage orthopedic trauma company that develops an intramedullary nailing system and distal targeting device.

CloSys

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CloSys develops hemostatic devices used for rapid vascular closure for anti-coagulated patients.

Patterson Companies

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Patterson Companies is an industry-leading specialty distributor serving the dental, veterinary and rehabilitation supply markets.

HealtheMed

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HealtheMed is a telemedicine company targeting Medicaid Special Needs Basic Care (SNBC) patients with medication adherence.

InterValve

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InterValve develops medical devices and technology for the catheter-based treatment of calcified aortic valve stenosis.

Circle Biologics

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Circle Biologics develops and markets biologic treatments and intra-operative biologic material management systems.

Smiths Medical

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Smiths Medical is one of the world’s leading manufacturers of medical products.

Prospex Medical

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Prospex Medical is a medical device incubator focused on innovating and incubating novel medical technologies.

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