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101 Best Missouri Software Companies and Startups

This article showcases our top picks for the best Missouri based Software companies. These startups and companies are taking a variety of approaches to innovating the Software industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top Missouri Software Startups

Data sourced from Crunchbase and SemRush.

Balto

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Increase conversions, deliver a world-class customer experience, and decrease ramp time with Balto’s real-time guidance for contact centers.

Mycroft

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Mycroft is a developer of an open source voice assistant platform designed to handle operating systems.

Adalo

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Adalo is a computer software company that specializes in the fields of Android, software, and information technology.

Daupler

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Daupler simplifies the way people communicate with local government and utilities.

Capacity

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Capacity is an AI-powered helpdesk that automates support for customers and employees.

BriteCore

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BriteCore is an enterprise-level insurance processing suite that combines core, data, and digital solutions into a single platform.

Curate

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Curate provides end-to-end event, COGS, and rental management services.

Bonfyre

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Bonfyre is a workplace culture platform that builds human connections in a remote workforce.

Essence Group Holdings

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Essence Group Holdings offers health insurance and software solutions necessary for health systems, health plans and provider organizations.

Denim Social

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Denim Social provides social media management and marketing automation software for customers.

Textel

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Textel offers a business texting technology that allows businesses to text their customers on their existing business phone numbers.

Coolfire

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Coolfire provides connected workstream collaboration software to enhance real-time event awareness, control, and response.

Simplifyy

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SaaS, Multifamily Technology, Proptech, RentTech

DisruptOps

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DisruptOps is a cloud security operations platform that helps customers find & fix security issues before they become incidents.

SpiderOak

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SpiderOak is a collaboration tool that develops a technology that eliminates entire categories of cyberattacks.

Paytient

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Paytient is an employer-sponsored payer of employee out-of-pocket medical, dental, pharmacy, vision, or veterinary expenses.

FUGA

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FUGA is the high-end technology partner for content owners and distributors.

Healthcare Fraud Shield

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Healthcare Fraud Shield is a provider of dynamic fraud, waste and abuse detection software solution.

Neocova

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Neocova is a financial services company that specializes in providing artificial intelligence, analytics, and other cloud-based systems.

SentiAR

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Digital health company with holographic AR platform for intraprocedural clinical use.

Benchmark Email

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Benchmark Email is a digital marketing company that specializes in email messaging and communication.

Boundless Spatial

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Boundless is a provider of open source product support, training, and core development to meet geospatial requirements.

Aspire Software

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Aspire Software develops business management software for landscaping, snow and ice management, and construction businesses.

BenchmarkONE

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BenchmarkONE develops software that automates sales and marketing activities to enable businesses to reach and retain customers.

Pepper

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Pepper offers an operating system and service delivery platform to empower enterprises to deploy sophisticated IoT marketplace solutions.

TopOPPS

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Artificial Intelligence for Sales Forecasting and Pipeline Management

ZAF Energy Systems

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ZAF Energy Systems develops battery technology that is safe, high in energy, low in cost and weight, and environment friendly.

Amdocs

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Amdocs is a developer and provider of customer experience systems for communications, media, and entertainment industries.

Aker Technologies

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Aker is an agriculture data company providing crop intelligence and in-season analytics.

Cerner

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Cerner Corporation is a supplier of healthcare information technology solutions, services, devices and hardware.

Homebase

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Your solution for smart apartment management and residence experience.

Tallyfy

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Tallyfy is beautiful workflow software that lets you document, track and improve all your repeatable processes

Ryvit

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Ryvit develops an integration software that delivers seamless flow of data between premise and software used in the construction industry.

Disruptel

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Disruptel is a visually-aware artificial intelligence that understands image and video content.

Mission Control

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Mission Control is a developer of an eSports platform used to create recreational gaming leagues for friends.

Strayos

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Strayos is a 3D aerial intelligence platform for Mining and Quarry blasting operations to reduce cost.

Exegy

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Exegy provides ultra-high performance, hardware-accelerated computing appliances that process market data for financial organizations.

Compatio

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Compatio is a software company that specializes in eCommerce, recommendation systems, store-branded apps, and retail software.

Advocado

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Advocado is a real-time cross-media optimization & audience platform that makes advertising perform better.

NeuroLutions

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The Company seeks to develop a revolutionary platform of devices, based on Brain Computer Interface (BCI) technology

MindMixer

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MindMixer helps communities grow their networks of engaged residents through easy-to-use online engagement software.

Well Principled

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Well Principled is an A.I. Management Consultant that predicts the buying behavior of every customer.

LendingStandard

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LendingStandard improves a lender’s ability to aquire, process, and fund a complex commercial loan transaction.

NEER

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Redefining Water Infrastructure Modeling and Asset Management through Machine Learning

TRIBUS

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TRIBUS provides technology, strategy, marketing and operations solutions for real estate brokerages around the world.

PolicyEngage

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Workflow Automation Software for Public Affairs. Connect legislative & regulatory tracking, advocate & donor engagement, & media monitoring.

Epharmix

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Epharmix is a digital healthcare company that creates clinically validated and condition-specific communication tools.

DivvyHQ

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DivvyHQ is a cloud-based, content planning, workflow, and collaboration platform.

SwipeSum

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At SwipeSum we are software-enabled payments consultants leveraging our proprietary software, Staitment. We’re your Chief Payments Officer.

TruQC

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TruQC is a cloud-based industrial painting quality control and documentation application for the iPad.

HealthMEDX

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HealthMEDX, Inc. offers home care, long-term care, and rehab software solutions. It offers CareMEDX, a suite of knowledge management.

eHawk

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eHawk is a monitoring platform that helps supervise criminal defendants.

Pathfinder Health Innovations

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Pathfinder Health Innovations is a comprehensive web-based software tool for supporting the implementation of ABA therapy.

homewav

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Homewav is the leader in providing reliable revenue to detention facilities with comprehensive inmate video visitation solutions & hardware.

Remetrik

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Better Royalty/Analytics/Data Software for Music Businesses

Banks Best Rates

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Tech Financial Organization

FitBark

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FitBark provides dog parents and pet care brands with deep, actionable insights into dog health and behavior.

gomingo

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Manufacturing analytics application that analyzes data from the factory floor to provide key metrics to improve performance and uptime

Rovertown

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Rovertown builds branded apps for c-stores looking to better connect with customers in an always-on world.

Foresite Healthcare

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Foresite Healthcare is a provider of healthcare technology solutions to healthcare professionals.

Qpass

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Qpass is a U.S.-based software provider that provides full cycle of activities for business systems and value-added data services.

Automotive Innovations

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Automotive Innovations builds software in the automotive industry that gives dealers actionable intelligent information.

FocalCast

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Live qualitative research platform with no downloads or plugins

Keybot

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Keybot is a smart rental access Robot that automates access for rental properties.

Rebate Bus, Inc.

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Rebate Bus provides software and support to business customers promoting the sale and implementation of energy-efficient products.

Jack Henry & Associates

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Jack Henry & Associates, Inc. provides integrated computer systems for in-house and outsourced data processing to commercial banks.

Radialogica

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Radialogica is a bioinformatics company providing software solutions for radiation oncology and the healthcare market.

PopBookings

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PopBookings is a cloud-based software that automates the hiring process for temporary and promotional staffing companies.

PlanIT Impact

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PlanIT Impact is a cloud-based web application that allows architects, designers, engineers, developers.

AppsCo Inc

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Appsco helps you manage access to your company applications and gives you meaningful insights over sensitive data flow.

Emerson

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Emerson is a global technology & engineering company providing innovative solutions for customers in industrial and residential markets.

HIPAAtrek

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HIPAA compliance is a long journey. We are just the guides to help your organization on that trek!

Recursive Labs

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We improve customer sales & service experiences (CX) with a fully integrated, visual customer engagement platform for web, mobile & IoT

FloEnvy

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FloEnvy is the premier software for cannabis cultivation

RF Controls

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RF Controls is uniquely positioned to usher in the Internet of Everything era.

TrackMy Solutions

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TrackMy Solutions is a software and mobile application company that provides a solution for people with medical implants.

Car-Part.com

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Provider of web solutions for auto recyclers in areas such as inventory searching, web design and hosting etc.

Cloud Commerce

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Cloud Products and Services for SMBs.

World Wide Technology

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World Wide Technology is a systems integrator, provides information technology and supply chain solutions.

AppNotch

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AppNotch provides individuals and companies with a resource to manufacture apps without software.

DSI®

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Cloud Inventory® Solutions and Mobile-First Supply Chain Apps for the Digital Economy.

pikazo

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Pikazo is at the very bleeding edge of neural network software

StockSwap

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StockSwap is a mobile app that allows users to share stock trades, thoughts, and repost news articles with friends and other users.

Brightergy

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Brightergy is a new kind of energy company that empowers organizations to take control over their energy – creation, cost, and consumption.

NOUS Imaging

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NOUS Imaging is a St. Louis-based startup has created a software-based biofeedback solution

FIRMM

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FIRMM is a real-time MRI quality metrics to reduce costs and improve quality. Jointly developed by the Fair (OHSU) & Dosenbach (WashU) labs.

HomeTraq

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HomeTraq is an online brokerage platform that connects potential homebuyer with a local real agent as well as schedules property showings.

Deep Water Software

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Email Receipt Pictures. Get Reports. Retailing Simplified.

SmashToast, Inc.

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Control your home from your phone.

BlueStrata EHR

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BlueStrata EHR provides simple and reliable solutions to long term care facilities giving them the opportunity

Bridge Software LLC

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Developer of Stagistics – cloud-based software and data aggregator connecting the home renovation industry to improve results for all

Truckily

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Truckily is a mobile application that enables users to find food trucks in their local community.

MetKnow, Inc.

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MetKnow is a patented flash card and quizzing application that helps members in organizations learn each other’s name.

Graematter

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Graematter offers a regulatory intelligence system that enables regulatory professionals to locate, analyze, and track related information.

WayLit

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WayLit provides immigration services based on Artificial Intelligence technology.

SlideBatch

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SlideBatch is an innovative new product that cuts through content overload on the web with a simple concept of a “Batch”.

Mediprocity

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Mediprocity is a mobile app that provides secure messaging services for the healthcare industry.

Blossom

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Blossom is a software company that connects all types of exchanges on the same marketplace.

Yurbuds

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Yurbuds develops a type of sport earphones that are custom fit for athletes, runners and music lovers.

GIVVER

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GIVVER provides a solution that enables users to tweet a donation to their organizations and causes.

Deck Internet Solutions

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Deck Internet Solutions is a cloud-based management platform that provides a better solution to the customer to become an eCommerce leader.

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