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101 Best Missouri Biotechnology Companies and Startups

This article showcases our top picks for the best Missouri based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top Missouri Biotechnology Startups

Data sourced from Crunchbase and SemRush.

Benson Hill

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Benson Hill is a provider of crop design platform to develop healthier and more sustainable food and ingredients.

Wugen

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Wugen is a developer of a novel CAR-T therapy platform intended for T-Cell Malignancies.

PierianDx

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PierianDx is catalyzing global adoption of genomic sequencing in healthcare

NewLeaf Symbiotics

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NewLeaf Symbiotics develops and commercializes the bacteria found in Pink Pigmented Facultative Methylotrophs.

Stereotaxis

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Stereotaxis develops robotic cardiology instrument navigation systems that enhances the treatment of arrhythmias and coronary diseases.

SentiAR

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Digital health company with holographic AR platform for intraprocedural clinical use.

Adarza BioSystems

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Adarza BioSystems develops a biological assay platform for measuring clinical and point-of-care samples.

Geneoscopy

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Geneoscopy is developing a screening methodology to noninvasively diagnose colorectal cancer using biomarkers in stool samples.

Covercress

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Covercress is a biotechnology company that manufactures an oilseed crop for food, bioenergy, and cattle feed.

MediBeacon

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MediBeacon is an optical diagnostic company providing clinicians with critical information that improve patient care.

C2N Diagnostics

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C2N Diagnostics, LLC is a privately held protein diagnostic and therapeutic discovery company.

Tioma Therapeutics

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Tioma Therapeutics is a venture-stage biopharmaceutical company.

EndoStim

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EndoStim is a medical device company developing therapeutics for gastrointestinal and urological neuro-muscular disorders.

Canopy Biosciences

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Canopy Biosciences aims to accelerate the commercialization of life science reagent tools and services through in-licensing.

Donald Danforth Plant Science Center

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Donald Danforth Plant Science Center is a non-profit research institute developing plant science solutions to improve human conditions.

NeuroLutions

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The Company seeks to develop a revolutionary platform of devices, based on Brain Computer Interface (BCI) technology

Appistry

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Appistry helps clinical labs, research institutions, and hospitals capitalize on genomics data.

Kypha

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Kypha develops technology and clinical products to improve monitoring and treatment of autoimmune and inflammatory diseases.

Nanoguard Technologies

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Nanoguard Technologies develops cold plasma technology for the treatment of grains.

Precision Virologics

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Precision Virologics is a St. Louis-based biotech startup.

BioSTL

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BioSTL builds regional capacity and fosters collaborative efforts to advance innovation,

Affigen

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A St. Louis startup developing drugs that target specific molecules in cancerous tumors.

Aptimmune

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Aptimmune is a biotechnology company that specializes on developing mucosal vaccines for swine.

Isto Technologies

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ISTO Technologies is an orthobiologics firm developing biologic products to regenerate and restore function to damaged cartilage and bone.

ImmunoPhotonics

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Minimally invasive therapeutic cancer vaccine for the treatment of metastatic solid tumors.

Keystone Bio

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Keystone Bio is a nextgen PharmaBiome biotech that has identified and is targeting a “one of a kind Inflammapath “.

Pepex Biomedical

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Pepex is a Biotechnology & Big Data Company

Euclises Pharmaceuticals

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Euclises Pharmaceuticals develops novel COX-2 inhibitors for the effective treatment of cancers in the lungs, colon, and pancreas.

RNAgri

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RNAgri is a startup that specializes in the production of ribonucleic acid and RNAi products.

Plastomics

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Plastomics is a biotech company developing a new and better way to make the next generation of biotech crops using chloroplast engineering.

ZYOMYX

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Zyomyx develops and commercializes diagnostic platforms, including a point-of-care test for HIV/AIDS.

Bacterioscan

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Bacterioscan offers an instrument for detecting and quantifying bacteria in fluid with on-board incubation.

GeneriCo

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GeneriCo is a generic drug company developing and marketing generic pharmaceuticals in the U.S.

Rex Animal Health

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Rex is take care animal health to the 21st century by making veterinary medicine and husbandry data driven.

Confluence Life Sciences

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Confluence Life Sciences is focused on rational drug designs to develop novel kinase inhibitors for use in human and animal healthcare.

Unleash Immuno Oncolytics

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Unleashing the immune response to treat cancer.

Mobius Therapeutics

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Mobius Therapeutics is an early-stage venture focused on ophthalmic surgery solutions.

Pluton Biosciences

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Pluton Biosciences is a biotech startup.

InnovaPrep

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InnovaPrep is engaged in product development, manufacturing, sales, service, and related out-licensing of collection of novel technologies.

Nanopore Diagnostics

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Developing a rapid bacterial diagnostic test to ensure physicians know exactly what they are treating before making an antibiotic decision

Vortex Surgical

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Vortex Surgical develops surgical disposables and instruments designed to improve the customer experience.

Elemental Enzymes

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Elemental Enzymes is an enzyme manufacturer based in Columbia, MO.

Akermin

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Akermin focuses on developing commercial applications in wireless sensors for military uses.

EternoGen

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EternoGen is a medical biotech company designing and manufacturing collagen scaffolds for soft tissue therapeutic applications.

MOgene

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MOgene is a provider of genomics services for academic, government, and industrial research groups and institutions.

Endevica Bio

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Endevica Bio is a biotechnology company that develops drugs to treat cachexia.

Self-screen

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Self-screen focuses on cervical cancer screening and prevention.

Kereos

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Kereos is a biotechnology company developing molecular imaging agents and therapeutics to treat cancer and cardiovascular diseases.

TSE Systems

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TSE Systems is a globally renowned manufacturer of high quality instruments for behavioral, metabolic and inhalation research.

Accuronix Therapeutics

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Accuronix Therapeutics is a biotech company that develops drug targeting technology to resolve issues in cancer therapy.

Hercules Pharmaceuticals

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Hercules Pharmaceuticals is a bio tech Start up

VaxNewMo

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VaxNewMo is an early stage biotechnological company.

MilliporeSigma

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MilliporeSigma is a technology company that develops, manufactures, and distributes various biochemicals and organic chemicals.

Opertech Bio

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Opertech Bio has developed a revolutionary approach to taste testing, a multi-billion dollar market covering the food and beverage.

Smart Diagnostics Systems

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Smart Diagnostics Systems modernizes diagnostics to accelerate advancements in the detection, interpretation, and prevention of disease.

SynerZ Medical

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SynerZ Medical is a medical device company providing treatment for obesity and type 2 diabetes.

Probiotic Holdings

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Probiotic develops bio-based products which are non-toxic, biodegradable biochemicals as replacement to synthetic, petroleum-based chemicals

Tansna Therapeutics

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Tansna Therapeutics is a developer of an oral anticonvulsant agent that reduces seizure frequency in patients with epilepsy.

GlucanBio

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GlucanBio, an early stage company that repurposes non-food biomass into high-value chemicals and biomaterials

Proviera Biotech

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Proviera Biotech is a developer and supplier of sustainable products for the leather industry.

Apertus Pharmaceuticals

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Apertus Pharmaceuticals is an API manufacturing company that provides controlled and non-controlled substance APIs.

Arch Innotek

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Arch Innotek is a biotechnology company that produces natural carotenoid antioxidants by fermentation in yeast.

DiscoveRX

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DiscoveRx is a company developing, manufacturing, and commercializing reagents.

Sinclair Research Ltd.

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Sinclair Research Ltd. is a company that offers specialty biomedical research services in a large range of species.

FutureFuel Corporation

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FutureFuel Corporation is a developer and producer of chemicals and biofuels.

Partek Inc.

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Partek is a software company that provides easy-to-use genomic data analysis solutions for scientists.

Ulrich Medical USA

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Ulrich Medical USA manufactures medical devices in the United States.

Divergence

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Divergence is a research and development company dedicated to the discovery of strategies for the control of parasites and other pests.

Companion Pharma

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Companion Pharma is an animal health product development company that develops formulations of prescription drugs for companion animals.

Children’s Mercy Hospital

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Children’s Mercy has been named one of the best places to work in Kansas City for a good reason.

BioMed Valley Discoveries, Inc.

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Scientific Discovery Development

Gallus BioPharmaceuticals

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Gallus Biopharmaceuticals, LLC, a contract manufacturer, supplies clinical and commercial bulk biologics to the biopharmaceutical industry

Sequoia Sciences

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Sequoia Sciences is a pharmaceutical company discovering and developing new medicines for the treatment of bacterial infections and cancers.

Mazen Animal Health

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Mazen Animal Health is a new company focused on developing, delivering and commercializing novel biological vaccines and therapeutics.

Array Bridge

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Array Bridge provides quality products and services for the pharmaceutical and biotechnology industry.

Tripos International

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Tripos Discovery Informatics engages in the identification and optimization of new compounds that have the potential to become drug

Jost Chemical Co.

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Jost Chemical Co. is a pharmaceutical company that provides inorganic salts products.

Lumara Health

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Lumara Health is focused on offering healthcare services to its patients.

Catapult Therapeutics

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Catapult Therapeutics is a privately held Dutch biotech company.

Viracor-IBT Laboratories

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Viracor-IBT Laboratories is dedicated to being the leading specialty diagnostics laboratory partner in allergy, immunology, and infectious

APT Therapeutics

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APT Therapeutics is a Biotechnology company located in 4041 Forest Park Ave., St. Louis, MO, United States.

OpenCell Technologies

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OpenCell Technologies provides efficient, high-throughput and scalable transfection tools to researchers in the Life Sciences.

Percayai

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Reimagining drug discovery by providing innovative augmented intelligence software

Orion Genomics

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Marketing molecular diagnostic products, epigenetics research tools and genomics and clinical research services to customers world-wide.

Dynalabs

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An analytical testing lab that tests pharmaceuticals.

BioZyme

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BioZyme develops and manufactures natural, proprietary products focused on animal nutrition, health, and microbiology.

MRIGlobal

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MRIGlobal is an independent organization performing research for government & industry on contract basis.

Scinomix

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About Scinomix provides laboratory automation solutions to customers in the Life Science Industry.

Sekisui XenoTech, LLC

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Sekisui XenoTech is a pharmaceutical company offering pharmaceutical safety testing and drug metabolism services.

HMS Health

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HMS Health is your trusted partner for biomedical equipment repair and clinical engineering services.

Sigma-Aldrich

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Sigma-Aldrich solves the problems in life science by collaborating with the global scientific community.

Cadre Bioscience

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Cadre Bioscience aims to accelerate the development of early-stage therapeutics for multiple technology assets.

Biotech X-Ray Inc

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Biotech X-Ray is a radiologic technologist, provides same-day, high-quality, portable diagnostic imaging services at the patient’s bedside.

Legacy Pharmaceutical Packaging, LLC

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Legacy Pharmaceutical Packaging is a pharmaceuticals company providing bottle filling, blistering, and compliance services.

2-BBB Medicines BV

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2-BBB Medicines BV is a created to develop medicines for the treatment of devastating brain diseases.

Confluence Discovery Technologies

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Confluence is a contract research organization providing mechanistic enzymology, target validation, characterization, and more.

Osteo-Pharma

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Osteo-Pharma is a technology platform

Facio Therapies

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Facio Therapies is a single-minded pharmaceutical company.

Chestnut Labs

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Chestnut Labs provides food testing laboratory services.

Gateway Biotechnology

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Gateway Biotechnology works to develop drugs for hearing disorders such as hearing loss and tinnitus.

PTC Laboratories

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Since 1996, PTC Laboratories offers genetic testing in multiple areas of expertise including forensics, relationship and pharmacogenetics.

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