This article showcases our top picks for the best Massachusetts based Therapeutics companies. These startups and companies are taking a variety of approaches to innovating the Therapeutics industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
Top Massachusetts Therapeutics Startups
Data sourced from Crunchbase and SemRush.
Pear Therapeutics
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Pear Therapeutics is a software-based digital therapeutics platform designed to treat disease and enhance the efficacy of pharmaceuticals.
Intellia Therapeutics
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Intellia Therapeutics is a genome editing company that develops curative gene-editing treatments.
Biofourmis
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Biofourmis is a biotechnology company that augments personalized care and therapies using digital therapeutics.
Relay Therapeutics
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Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.
Synlogic
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Synlogic is a biotechnology company that develops synthetic biotic medicines to perform metabolic functions to treat diseases.
Cedilla Therapeutics
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Cedilla Therapeutics is a biotechnology company that develops targeted small molecules for the treatment of cancer and other diseases.
Beam Therapeutics
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Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.
Xilio Therapeutics
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Xilio Therapeutics is a biopharmaceutical company focused on developing highly-potent, targeted immuno-oncology therapeutics.
Sarepta Therapeutics
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Sarepta Therapeutics focuses on the discovery and development of precision genetic medicine to treat rare diseases.
Stealth BioTherapeutics
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Stealth BioTherapeutics is a clinical-stage biotechnology company focused on the discovery and commercialization of novel therapies.
Akili Interactive Labs
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Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games.
Spero Therapeutics
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Spero Therapeutics is developing first in class therapeutics for treatment of Gram-negative infections.
Intergalactic Therapeutics
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Intergalactic Therapeutics is an ATP company, is revolutionizing gene therapies with a novel non-viral platform.
SeLux Diagnostics
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SeLux Diagnostics is a developer of the next-generation phenotyping platform that enables personalized antibiotic therapies for patients.
Laronde
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Laronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.
Finch Therapeutics
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Finch Therapeutics is a microbiome development company that serve patients with serious unmet medical needs.
Agenus
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Agenus develops and commercializes immunotherapies and vaccines for cancer and infectious diseases.
Skyhawk Therapeutics
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Skyhawk Therapeutics is a provvider of small molecule therapeutics designed to offer therapies that correct RNA expression.
Flexion Therapeutics
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Flexion Therapeutics is a biotechnology company that develops long-lasting intra-articular injection therapies to treat osteoarthritis.
Stoke Therapeutics
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Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for the treatment.
Rectify Pharmaceuticals
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Rectify Pharmaceuticals is a biotechnology company developing Positive Functional Modulators (PFMs), disease-modifying therapeutics.
C4 Therapeutics
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C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.
Tango Therapeutics
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Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.
SAGE Therapeutics
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SAGE Therapeutics develops and delivers novel medicines for most debilitating and disabling central nervous system disorders.
Translate Bio
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Translate Bio is a biotechnology company that specializes in biotechnology, RNA therapeutics, and rare diseases.
TScan Therapeutics
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TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.
1910 Genetics
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1910 Genetics is a biotechnology company integrating AI, computation, and biological automation to improve drug development.
Alnylam Pharmaceuticals
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Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
Groups Recover Together
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Groups Recover Together provides accessible and affordable medication-assisted treatment (MAT) for opioid addiction.
Nimbus Therapeutics
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Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company.
Cerevel Therapeutics
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Cerevel Therapeutics is a biopharmaceutical company.
MOMA Therapeutics
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MOMA Therapeutics operates as a biotechnology company.
Elevian
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Elevian develops medicines that restore youthful regenerative capacity with the potential to treat and prevent many age-related diseases.
Repertoire Immune Medicines
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Repertoire Immune Medicines is a clinical stage biotechnology company.
SQZ Biotech
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SQZ Biotech features a cell engineering technology designed to deliver a diverse set of materials into patient cells.
Ribon Therapeutics
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Ribon Therapeutics is a biotechnology company focused on the development of therapeutics treatments targeting stress support pathways.
Apellis Pharmaceuticals
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Apellis Pharmaceuticals focuses on developing novel therapeutics and drug delivery technologies to address chronic inflammatory diseases.
Kymera Therapeutics
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Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
Seres Therapeutics
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Seres Therapeutics is a microbiome therapeutics company focused on discovering and developing Ecobiotic therapeutic products.
Mersana Therapeutics
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Mersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines.
Tarveda Therapeutics
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Tarveda Therapeutics is a developer of miniature drug conjugates designed for the treatment of patients with a wide range of solid tumors.
Allurion Technologies
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Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
Magenta Therapeutics
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Magenta Therapeutics is a new biotechnology company developing therapeutics that unlock the power of stem cell biology.
Rhythm Pharmaceuticals
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Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
KSQ Therapeutics
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KSQ Therapeutics is using CRISPR technology within a powerful drug discovery engine to enable high-confidence drug development.
Candel Therapeutics
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Candel Therapeutics develops cancer immunotherapies designed to improve the lives of cancer patients and their families.
Evelo Biosciences
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Evelo Biosciences is dedicated to improving the lives of patients globally through the development of monoclonal microbials.
Adagio Therapeutics
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Adagio Therapeutics offers research and development of therapeutic pharmaceuticals related to COVID-19.
Dewpoint Therapeutics
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Dewpoint Therapeutics is a biotech company which develop a drug platform that targets biomolecular condensates.
Fractyl Health
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Fractyl Health is a biotechnology company that provides curative therapies for metabolic diseases.
Rubius Therapeutics
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Rubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.
Decibel Therapeutics
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Decibel Therapeutics is a hearing company focused on discovering and developing new medicines to protect, repair, and restore hearing.
Axcella
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Axcella is a biotechnology company providing therapeutics development solutions.
Tessera Therapeutics
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Tessera Therapeutics is an early-stage life sciences company.
Affinia Therapeutics
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Affinia Therapeutics is a biotechnology company developing transformative AAV gene therapies for people with devastating diseases.
Pandion Therapeutics
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Pandion Therapeutics develops innovative modular proteins, antibodies, and bispecifics for autoimmune and inflammatory diseases.
X4 Pharmaceuticals
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X4 Pharmaceuticals a clinical-stage oncology company developing best-in-class oral small molecule CXCR4 antagonists for the treatment.
Intrinsic Therapeutics
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Intrinsic Therapeutics is a medical device company that develops therapies to treat disc herniations in the spine for discectomy patients.
Orna Therapeutics
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Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA (oRNA) therapeutics to treat various diseases
Strand Therapeutics
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Strand Therapeutics is a developer of a biotechnology platform intended to create gene therapies powered by synthetic biology.
Fulcrum Therapeutics
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Fulcrum Therapeutics is a biotechnology company developing new medicines to deliver a new future to patients.
LifeMine Therapeutics
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Discovering powerful new drugs from eukaryotic microbes by combining Genomics with AI and Synthetic Biology.
Garuda Therapeutics
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Garuda Therapeutics is developing off-the-shelf hematopoietic stem cell (HSC) therapies to treat severe and life-threatening diseases.
Jounce Therapeutics
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Jounce Therapeutics is developing cancer immune-therapies to harness the immune system to attack cancerous cells and tumors.
TCR2
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TCR2 is a discovery stage pharmaceutical company that developed a unique proprietary TRuC™ platform.
Mevion Medical Systems
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Mevion Medical Systems develops radiation therapies for the treatment of cancer.
Medrhythms
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Medrhythms utilizes sensors, music, and software to develop evidence-based, neurologic interventions to measure and improve walking.
Cogent Biosciences
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Cogent Biosciences is a biopharmaceutical company that develops therapies for solid cancer tumors.
CAMP4 Therapeutics
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CAMP4 Therapeutics is a biotechnology company.
Morphic Therapeutic
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Morphic Therapeutic is a biotechnology company developing a new generation of oral integrin therapies.
Immunitas Therapeutics
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Immunitas Therapeutics is a single cell genomics-based drug discovery company that modulates oncology targets.
Foghorn Therapeutics
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Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express,
Akebia Therapeutics
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Akebia Therapeutics develops treatments for ischemia and vascular diseases.
Ikena Oncology
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Ikena Oncology is a biotechnology company that advances new immunometabolic therapies for cancer.
Vigil Neuroscience
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Vigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases.
ConforMIS
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ConforMIS develops personalized, patient-specific implants and instrumentation for knee-related therapeutics.
Talaris Therapeutics
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Talaris Therapeutics is a operator of a biotechnology company engaged in the development of innovative cellular therapies.
Nuvalent
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Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer.
Jnana
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Jnana Therapeutics is a biotechnology company developing therapies that transform the lives of patients.
Oncorus
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Oncorus is an immuno-oncology company developing oncolytic viruses to fight cancer.
Imara
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Imara is provider of novel therapeutics for the people living with sickle cell disease and hemoglobinopathies.
Keros Therapeutics
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Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.
AVEO Oncology
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AVEO is a biopharmaceutical company that offers drug development strategies for targeted cancer therapeutics.
Yumanity Therapeutics
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Yumanity Therapeutics is a biotechnology company that transforms drug discovery for diseases caused by protein misfolding.
Deciphera Pharmaceuticals
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Deciphera Pharmaceuticals focuses on improving kinase inhibitor treatments.
Elicio Therapeutics
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Elicio Therapeutics develops an immuno-tumor vaccine to treat cancer.
Remix Therapeutics
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Remix Therapeutics is a biotechnology company that develops novel small molecule therapies.
Checkmate Pharmaceuticals
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Checkmate Pharma is a clinical stage biopharmaceutical company developing a new approach for cancer immunotherapy.
Casma Therapeutics
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Casma Therapeutics is a biotechnology company harnessing the natural cellular process of autophagy to design new medicines.
Solarea Bio
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Solarea Bio develops microbial therapeutics aimed to treat indications derived from chronic inflammation to aid human health.
Scholar Rock
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Scholar Rock is discovering and developing a new class of biologic therapies.
Semma Therapeutics
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Semma Therapeutics was founded to develop transformative therapies for Type 1 diabetes patients.
Compass Therapeutics, Inc.
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Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.
Werewolf Therapeutics
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Werewolf Therapeutics operates as an oncology biotherapeutics company.
Alzheon
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Alzheon is a clinical-stage biotechnology company focused on brain health, memory and aging, developing a pipeline of innovative.
Goldfinch Biopharma
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Goldfinch is a clinical-stage biotech company focused on discovering and developing precision therapies for patients with kidney disease.
Cerevance
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Cerevance is a developer of novel therapeutics intended to advance new medicines for serious neurological diseases.
Abata Therapeutics
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Abata Therapeutics is a biotech company focused on translating the biology of regulatory T cells (Tregs) into transformational medicine.
Abpro
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Abpro is a biotechnology company focused on therapeutics, diagnostics, and research.