This article showcases our top picks for the best Massachusetts based Life Science companies. These startups and companies are taking a variety of approaches to innovating the Life Science industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
Top Massachusetts Life Science Startups
Data sourced from Crunchbase and SemRush.
Algorand
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Algorand is a scalable, secure and decentralized digital currency and transactions platform.
Thermo Fisher Scientific
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Thermo Fisher Scientific is a science and pharma service provider of laboratory information management & scientific data systems.
SOPHiA GENETICS
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SOPHiA GENETICS is a biotechnology firm that aims to support healthcare professionals by maximizing the power of data-driven medicine.
Virtusa
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Virtusa is a leading worldwide provider of next-gen information technology (IT) consulting and outsourcing services
nference
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nference.inc, provides an AI based software platform that synthesizes siloed biomedical knowledge for insights and makes it computable.
Intergalactic Therapeutics
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Intergalactic Therapeutics is an ATP company, is revolutionizing gene therapies with a novel non-viral platform.
Akoya Biosciences
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Akoya Biosciences is a spatial biology company offering solutions for high-parameter tissue analysis from biomarker discovery to validation.
Voyager Therapeutics
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Voyager Therapeutics is a gene therapy company developing treatments for fatal and debilitating diseases of the central nervous system
TetraScience
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TetraScience is an R&D cloud data management company that empowers transformation in life sciences and drug discovery.
Quanterix
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Quanterix is a platform for single molecule analysis that supports clinical diagnostics, drug development, and life science researches.
Kytopen
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Kytopen developer of a cell therapy platform for non-viral delivery of molecules into hard-to-transfect immune cells.
Rectify Pharmaceuticals
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Rectify Pharmaceuticals is a biotechnology company developing Positive Functional Modulators (PFMs), disease-modifying therapeutics.
EGenesis
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EGenesis focuses on leveraging genome editing technology to deliver safe and effective human transplantable cells, tissues, and organs.
Repertoire Immune Medicines
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Repertoire Immune Medicines is a clinical stage biotechnology company.
SQZ Biotech
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SQZ Biotech features a cell engineering technology designed to deliver a diverse set of materials into patient cells.
Cellarity
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Cellarity’s platform digitizes the molecular information in cells to elucidate how they behave in health and disease.
Alloy Therapeutics
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Alloy Therapeutics is a biotech company that makes medicine by democratizing access to foundational drug discovery platforms and services.
Orbita
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Orbita provides software to improve patient engagement in digital healthcare through voice-first and conversational AI solutions.
Sherlock Biosciences
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Sherlock Biosciences is an engineering biology company offering unparalleled breadth and versatility for diagnostic solutions.
Axcella
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Axcella is a biotechnology company providing therapeutics development solutions.
Affinia Therapeutics
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Affinia Therapeutics is a biotechnology company developing transformative AAV gene therapies for people with devastating diseases.
Kojin Therapeutics
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Kojin is a biopharmaceutical company that develops new targeted therapeutics based on cell state and ferroptosis biology.
AffyImmune Therapeutics
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AffyImmune Therapeutics is a biopharmaceutical company developing genetically engineered immune cells to fight cancer.
Strand Therapeutics
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Strand Therapeutics is a developer of a biotechnology platform intended to create gene therapies powered by synthetic biology.
SmartLabs
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SmartLabs builds and operates enterprise-grade labs, including multi-use R&D labs, vivariums, process development, and manufacturing suites.
LifeMine Therapeutics
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Discovering powerful new drugs from eukaryotic microbes by combining Genomics with AI and Synthetic Biology.
Flare Therapeutics
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Flare Therapeutics is a biotechnology company targeting transcription factors to discover precision medicines for cancer and other diseases.
Broad Institute
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The Broad Institute brings together a diverse group of individuals from across its partner institutions to confront biomedical challenges.
Life Biosciences
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Life Biosciences is a developer of drugs designed to promote longevity and find treatments for age-related diseases.
Garuda Therapeutics
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Garuda Therapeutics is developing off-the-shelf hematopoietic stem cell (HSC) therapies to treat severe and life-threatening diseases.
TCR2
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TCR2 is a discovery stage pharmaceutical company that developed a unique proprietary TRuC™ platform.
Syros Pharmaceuticals
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Syros Pharmaceuticals is a life sciences company that focuses on treating diseases by mapping gene regulatory circuits.
Area9 Lyceum
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Area9 Lyceum is a cloud-based educational platform to provide online learning modules for schoolchildren, students and professionals.
Arbor Biotechnologies
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Unlocking nature’s biodiversity to create transformative products in human health and sustainability
Immunitas Therapeutics
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Immunitas Therapeutics is a single cell genomics-based drug discovery company that modulates oncology targets.
Foghorn Therapeutics
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Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express,
Leap Therapeutics
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Leap Therapeutics is a clinical-stage biopharmaceutical company.
Black Diamond Therapeutics
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Black Diamond Therapeutics is a precision oncology medicine company pioneering the discovery and development of small molecule.
Elucidata
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Elucidata delivers ML-ready biomedical molecular data that is curated to accelerate drug discovery.
Scorpion Therapeutics
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Scorpion Therapeutics is a precision oncology company that broadens the reach and impact of precision medicine for cancer patients.
Conagen
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Conagen, a biotechnology company that focuses on bio-production of ingredients for food, pharmaceutical, and renewable materials industries.
Vigil Neuroscience
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Vigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases.
Surface Oncology
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Surface Oncology was created to advance next-generation approaches to cancer immunotherapy based on proprietary insights.
Nuvalent
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Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer.
Platelet BioGenesis
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Platelet BioGenesis specializes in the fields of biotechnology, platelets, and drug discovery.
Ventus Therapeutics
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Ventus Therapeutics is a biopharmaceutical company developing novel small molecule medicines that target the innate immune system
Glympse Bio
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Glympse Bio is a biotechnology company that transforms disease detection and predict treatment response.
Variantyx
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Variantyx offers a comprehensive set of advanced genomic diagnostic products and services with a focus on whole genome sequencing.
Ovation
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Ovation is a scientific data company providing a cloud-based LIMS for molecular diagnostic laboratories.
Renovia
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Renovia is a developer of prescription digital therapeutics that focuses on improving the lives of women with pelvic floor disorders.
Pyramid Biosciences
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Pyramid Biosciences is a provider of biotechnological services.
Q-State Biosciences
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Q-State has developed world-leading technologies and proprietary approaches for probing rare and genetic CNS conditions.
New Health Sciences
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New Health Sciences develops a technology to extend the shelf life of refrigerated red blood cells using novel storage methods.
Senda Biosciences
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Senda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans.
Werewolf Therapeutics
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Werewolf Therapeutics operates as an oncology biotherapeutics company.
Cerevance
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Cerevance is a developer of novel therapeutics intended to advance new medicines for serious neurological diseases.
Atalanta Therapeutics
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Atalanta Therapeutics is a biotechnology company pioneering new treatment options for neurodegenerative diseases.
Aktis Oncology
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Aktis Oncology is a biotechnology company discovering and developing a novel class of targeted radiopharmaceuticals.
AavantiBio
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AavantiBio is a biopharmaceutical company that provides gene transfer and gene editing therapies to treat genetic diseases.
Monocl
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Monocl empowers life science professionals with the complete global expert solution for impactful outreach and strategic engagement.
HotSpot Therapeutics
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HotSpot Therapeutics is a developer of a therapy platform designed to discover medicines and provide proper treatment.
Aerovate Therapeutics
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Aerovate Therapeutics is a biotechnology company focused on developing drugs for rare cardiopulmonary disease.
Clora
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Clora is an intelligent platform that matches life science companies with flexible, on-demand expertise.
Myeloid Therapeutics
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Myeloid Therapeutics is an immunology company focused on combining immunologic insights with cutting-edge technologies.
iSpecimen
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iSpecimen is the marketplace for human biospecimens, providing researchers with the samples they need from the patients they want.
Collegium Pharmaceutical
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Collegium Pharmaceutical is a specialty pharmaceutical company focused on the development of products for the treatment of chronic pain.
nQ Medical
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nQ Medical is a neurotechnology company allowing Data Defined Disease Management via digital biomarkers using AI.
SalioGen Therapeutics
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SalioGen advances in genetic therapies using its Exact DNA Integration Technology platform, a mammal-derived genome engineering technology.
Apic Bio
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Apic Bio is a gene therapy company that develops treatment options for rare, undertreated neurological and liver diseases.
Akero Therapeutics
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Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.
Emulate
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Emulate creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health.
Aulos Bioscience
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Aulos Bioscience is dedicated to revolutionizing patient care in cancer with highly differentiated immuno-oncology therapeutics.
Twentyeight-Seven Therapeutics
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Twentyeight-Seven Therapeutics is a developer of microRNAs designed to target regulatory proteins.
Bicara Therapeutics
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Bicara Therapeutics is developing a pipeline of bifunctional antibodies that exploit the recent advances in immuno-oncology.
Walden Biosciences
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Walden Biosciences is a biotechnology company focused on transforming the treatment of kidney disease.
Hopewell Therapeutics
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Hopewell Therapeutics is a Synthetic Lipid-based drug delivery company for gene therapy and gene editing.
Hydra Biosciences
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Hydra Biosciences develops novel drugs to treat pain, inflammation, cardiovascular and other diseases using ion channels.
Mercy BioAnalytics
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Mercy BioAnalytics is a biotechnology company that aims to improve and save the lives of people through the early detection of cancer.
Eirion Therapeutics
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Eirion Therapeutics is a clinical-stage biopharmaceutical company that is developing next-generation prescription products.
Samsara Therapeutics
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Samsara Therapeutics is a biopharmaceutical company that aims to discover therapeutics to treat rare genetic and neurodegenerative disease.
Meenta
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Our vision is to make all of the world’s scientific equipment and clinical tests accessible to everyone.
Civetta Therapeutics
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Civetta Therapeutics is a cancer therapeutics company to advance new medicines through small molecule targeting of beta-propeller domains.
Totient
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Totient is an AI-driven biotechnology company that leverages tertiary lymphoid structures.
Thrive Bioscience
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Thrive sells instruments and software that automate with extensive imaging, analytics, and AI manual and stem cell culture.
EdenRoc Sciences
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EdenRoc Sciences is a privately backed holding or operating company managing bioscience and pharmaceutical startup companies.
Zikani Therapeutics
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Zikani Therapeutics is a new anti-infective company founded to advance groundbreaking technology.
seqWell
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SeqWell’s is a biotechnology company that specializes in the fields of gene sequencing and laboratory services.
Aviceda Therapeutics
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Aviceda Therapeutics is a late-stage, pre-clinical biotech company developing drugs for treating glyco-immune diseases.
Civitas Therapeutics
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Civitas Therapeutics is a biopharmaceutical company that focuses on developing pulmonary delivery therapies.
Ajax Therapeutics
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Ajax Therapeutics is a biotechnology company developing therapies to target cytokine signaling pathways that drive hematologic malignancies.
Tego
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Tego is a complete solution for asset tracking and data management, at the edge.
Proclara Biosciences
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Proclara is pioneering a new approach to treating neurodegenerative diseases.
Imbria Pharmaceuticals
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Imbria Pharmaceuticals is a biotechnology company with locations in San Diego, CA, and Boston, MA.
Mitra Biotech
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Mitra Biotech is a biotechnology company that specializes in providing personalized cancer treatment.
Courtagen Life Sciences
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Courtagen Life Sciences is a biotech company that provides proteomic and genomic products and services to the life sciences industry.
Humedica
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Humedica is a healthcare informatics company providing SaaS-based clinical business intelligence solutions.
LabMinds
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Solution Preparation via Automation – The Revo ® solution preparation system utilizes robotics, artificial intelligence and machine learning
Aptus Health
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Aptus Health provides digital health engagement solutions for healthcare providers and patients.
Nereid Therapeutics
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Nereid Therapeutics is discovering new disease treatments by applying research and technologies in biomolecular condensates.
MitoLab
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MitoLab is a biotechnology company building a scalable platform for mitochondrial genome engineering.
Flex Pharma
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Flex Pharma develops clinically proven products and treatments for muscle cramps and spasms.