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101 Best Maryland Biotechnology Companies and Startups

This article showcases our top picks for the best Maryland based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top Maryland Biotechnology Startups

Data sourced from Crunchbase and SemRush.

Novavax

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Novavax is a clinical-stage biotechnology company focused on the discovery and development of innovative vaccines.

Haystack Oncology

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Haystack Oncology enables precision oncology to optimize treatment strategies.

Arcellx

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Arcellx is a clinical-stage biotechnology company that provides patients with immune cell therapies.

Sirnaomics

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Sirnaomics is a biopharmaceutical company developing therapeutics for critical human diseases by using RNA interference technology.

National Institutes of Health

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National Institutes of Health is a biomedical research facility that focuses on biomedical and health-related research.

GeneDx

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GeneDx, a division of BioReference Laboratories, is a global industry in genetics and genomics, providing testing to patients and families.

b.well Connected Health

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b.well Connected Health provides an integrated solution for consumer engagement, holistic health management, and cost containment.

REGENXBIO

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REGENXBIO develops adeno-associated viral vector-based therapeutics and research tools, offering NAV, a recombinant AAV-vector.

Precision Medicine Group

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Precision Value & Health is engineered to bring expertise to every juncture of the innovation and commercialization continuum.

TissueGene

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TissueGene is a biopharmaceutical company focused on developing regenerative therapies for the treatment of various orthopedic disorders.

Emergent BioSolutions

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Emergent BioSolutions develops, manufactures, and delivers a portfolio of medical countermeasures for biological and chemical threats.

NextCure

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NextCure is a biopharmaceutical company focused on discovering and developing next generation immuno-oncology-based drugs.

OpGen

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OpGen is a precision medicine company utilizing molecular diagnostics and bioinformatics to help combat infectious disease.

Senseonics

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Senseonics is a medical device startup company that focuses on the design, development, and commercialization of glucose monitoring systems.

Adaptive Phage Therapeutics

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Adaptive Phage Therapeutics provides therapeutic services intended to treat multi-drug resistant pathogenic bacteria.

Precigen

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Precigen is a life sciences company researching and developing bio-therapeutic control systems to minimize toxicity.

Integrated BioTherapeutics

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Integrated BioTherapeutics focuses on the discovery of novel vaccines and therapeutics for emerging infectious diseases.

RoosterBio

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RoosterBio is a biotechnology company, offers synthetic biology and regenerative medicine.

Gain Therapeutics

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Gain Therapeutics is a biotech company developing pharmacological chaperones drugs designed to treat rare metabolic disorders.

Personal Genome Diagnostics

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Personal Genome Diagnostics develops a patient-specific analysis of the cancer genome by using advanced tools and technologies.

Precision for Medicine

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Precision for Medicine is a specialized scientific services company helping life science innovators develop medical products.

PaxVax

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PaxVax is a start-up developing candidate oral vaccines for key infectious diseases.

Supernus Pharmaceuticals

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Supernus Pharmaceuticals is focused on developing and commercializing products for the treatment of central nervous system.

ValenzaBio

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ValenzaBio is developing safe and effective treatment options for patients with autoimmune and inflammatory diseases.

NexImmune

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NexImmune is a biopharmaceutical company developing novel immuno-therapeutics based on the proprietary artificial immune technology.

American Gene Technologies International

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AGT is pioneering gene therapy solutions to achieve permanent cures for human diseases, including a possible cure for HIV in clinical trials

SalubrisBio

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SalubrisBio is a clinical-stage biotechnology company dedicated to discovering and developing novel antibody and protein-based therapeutics.

BrainScope Company

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Brainscope is a medical neurotechnology company that improves brain health.

Vita Therapeutics

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Vita Therapeutics is a cell engineering company that develops life-transformative treatments.

Aziyo Biologics

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Aziyo is a developer of customized tissue products intended to restore health and mobility to the greatest number of patients.

Sensei Biotherapeutics

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Sensei Biotherapeutics is a clinical-stage biotechnology company specializing in the field of next-generation cancer immunotherapies.

RNAimmune

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RNAimmune is a biopharmaceutical company specializing in the discovery and development of mRNA-based therapeutics and vaccines.

Previse

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Previse is a life sciences company focused on the development and commercialization of diagnostic tests for cancer prevention.

20/20 Gene Systems

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20/20 GeneSystems (‘20/20’) was founded in May of 2000 to develop and promote an innovative proteomics product line that provides drug

Osiris Therapeutics

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Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions.

Altimmune

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Altimmune focused on the development of products to stimulate robust and durable immune responses for the prevention.

OncoImmune

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OncoImmune is a clinical-stage biopharmaceutical company that develops solutions for the treatment of cancer.

NeuralStem

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Neuralstem, a biotherapeutics company, aims to apply stem cell research and technology to treat diseases of the central nervous system.

GlycoMimetics

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GlycoMimetics is a biopharmaceutical company designing and developing small molecule therapeutics to treat various cancers.

Cartesian Therapeutics

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Pioneering Potent, Safer Cell Therapy in and Beyond Oncology

CSA Medical

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CSA Medical is a provider of innovative spray cryotherapy medical device solutions.

Northwest Biotherapeutics

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Northwest Biotherapeutics is a biotechnology company focused on developing and commercializing immunotherapy products to treat cancer.

Neuraly

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Neuraly is a startup biotech company.

VLP Therapeutics

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VLP is a biotech company with a mission to address unmet medical needs worldwide and expand the frontiers of vaccine treatment.

National Spine & Pain Centers

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National Spine & Pain Centers provides administrative services to interventional pain management clinics.

CoapTech

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CoapTech is an early-stage medical device company aiming to improve medical care delivery for patients young and old around the world.

MaxCyte

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MaxCyte specializes in cell modification technologies that enable the discovery, development, and manufacture of various classes.

Sonavex

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Sonavex is a developer of an imaging technology designed to visualize and quantify critical data to detect anastomotic blood clots.

RS BioTherapeutics

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RS BioTherapeutics is a research, development, and commercialization company focused on pulminary diseases.

BioFactura

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BioFactura is a biopharmaceutical research and manufacturing company

InventWood

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InventWood develops cellulose-based materials for environmental.

NeuroCytonix

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NeuroCytonix is a biomedical technology company that is centered on tissue creation and regeneration.

CellPhire

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Cellphire has developed a proprietary method for the stabilization of blood in the dry state

CASI Pharmaceuticals

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CASI focus on building a pipeline through mutually beneficial business development transactions.

Synthetic Biologics

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Synthetic Biologics is a biotechnology company developing biologics for the prevention and treatment of serious infectious diseases.

Ravgen

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Ravgen is a biotechnology company that specializes in non-invasive prenatal diagnostic testing.

TeraImmune

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Developer of cell therapeutics created for autoimmune diseases and immune-related disorders.

AsclepiX Therapeutics

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AsclepiX Therapeutics is a biotech company that develops novel therapeutics to revolutionize the treatment of retinal diseases and cancer.

Elixirgen Therapeutics

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Elixirgen Therapeutics is a biotechnology company focused on the development of therapies for genetic diseases and vaccines.

Veralox Therapeutics

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Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes.

Cerecor

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Cerecor discovers, develops and commercializes neuroscience drugs.

MyMD

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MyMD is a clinical-stage pharmaceutical company focused on the development of drug products.

Avalo Therapeutics

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Avalo Therapeutics is a clinical-stage biopharmaceutical company.

Seraxis

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Seraxis is a privately owned biotechnology company.

Origene Technologies

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OriGene Technologies is a research tool company that provides a commercial collection of full-length human cDNAs.

Nuo Therapeutics

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Nuo Therapeutics develops biological therapies to address the areas of wound care, inflammation, and angiogenesis.

Intralytix

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Intralytix is a biotechnology company focused on the discovery, production and marketing.

Delfi Diagnostics

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Delfi Diagnostics detects cancer early, when it is most curable, using high precision non-invasive blood tests.

miRecule

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MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics.

Vigene Biosciences

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Vigene develops gene delivery technologies with the mission to advance biomedical research and to make gene therapy affordable.

Gliknik

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Gliknik develops therapies for patients with cancer and immune disorders.

Remedy Plan Therapeutics

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Remedy Plan is a pre-clinical cancer therapeutics company developing first-in-class small molecule drugs that differentiate cancer cells.

NovaSom

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NovaSom provides obstructive sleep apnea home testing devices with cardio-respiratory monitoring ability.

CiVi Biopharma

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CiVi Biopharma is a clinical stage research and development biotechnology company whose mission is to create novel cardiovascular.

CosmosID

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CosmosID is a bioinformatics company focused on rapid identification of microorganisms in metagenomic samples.

Synaps Dx

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Synaps Dx focuses on the research, development and commercialization for neurodegenerative disorders including Alzheimer’s Disease.

VerImmune

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VerImmune is an Immuno-Oncology company developing a first-in-class cancer therapy known as Anti-tumor Immune Redirection.

RegeneRx

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RegeneRx is a biopharmaceutical company that designs, researches, and develops novel peptides targeted at diseases with unmet medical needs.

Glyscend

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Glyscend develops a revolutionary approach to treating type 2 diabetes.

Foundation Fighting Blindness

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The Foundation intends to provide preventions, treatments & cures for people affected by entire spectrum of retinal degenerative diseases.

Vaccinogen

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Vaccinogen manufactures vaccines and other immunotherapeutic products for cancers and infectious diseases.

Sisu Global Health

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Sisu is a medical device company that designs and commercializes medical devices with and for emerging markets.

Profectus Biosciences

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Profectus Biosciences is a R&D company developing vaccine and small molecules to treat and prevent viral diseases and cancers.

Lifesprout

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LifeSprout offers revolutionary products for soft tissue replacement and regeneration

HeMemics Biotechnologies, Inc.

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The company develops a low-cost biosensor platform with graphene-based sensors to detect multiple pathogens in one test within 2 minutes.

The Howard Hughes Medical Institute

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The Howard Hughes Medical Institute, a non-profit medical research organization, aims to advance biomedical research and science education.

Akonni Biosystems

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Akonni Biosystems is a biotechnology company that develops and manufactures, genetic testing devices.

Novel Microdevices

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Novel Microdevices is a medical device startup that develops a handheld point-of-care medical device to facilitate molecular diagnostics.

ReGelTec

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ReGelTec is a medical device company.

Breethe

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Breethe is a medical device company that develops a compact artificial lung for patients with acute and chronic lung problems.

Cytimmune Sciences

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CytImmune Sciences focuses on the discovery, development and commercialization of multifunctional, tumor-targeted therapies.

Silvec Biologics

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Silvec Biologics offers therapy for trees using RNA-based molecules.

RevivBio

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RevivBio is a biotechnology company that focuses on microbial innovation.

Shuttle Pharmaceuticals

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Shuttle Pharmaceuticals is a clinical-stage pharmaceutical company utilizing proprietary technology to develop novel therapies.

Minnowtech

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Minnowtech develops aquaculture technologies to maximize aquafarmers’ cultivation efforts using integrated sensor-based systems.

Clear Guide Medical

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Clear Guide Medical is a privately-held company

AAVogen

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AAVogen is a biotech startup that develops gene therapeutics for muscle wasting diseases.

RLL

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RLL LLC is a biotechmology company that researches and manufactures high quality phytochemicals and extracts worldwide.

SynerGene Therapeutics

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SynerGene Therapeutics is a biotechnology company with focuses on developing gene-based nanotech cancer therapeutics and diagnostics.

J. Craig Venter Institute

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J. Craig Venter Institute is a non-profit organization engaged in the research of genomics.

Vixiar Medical

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Vixiar Medical develops non-invasive, cost-effective devices and systems for monitoring cardiopulmonary diseases.

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