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101 Best Connecticut Biotechnology Companies and Startups

This article showcases our top picks for the best Connecticut based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

Top Connecticut Biotechnology Startups

Data sourced from Crunchbase and SemRush.

HistoRx

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HistoRx is a biotech company developing personalized medicine to improve individualized patient care.

BioSafe Systems, LLC

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BioSafe Systems, LLC is a chemical company manufacturing biodegradable disease-control products.

Avara Norman Pharmaceutical Services

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Avara Norman Pharmaceutical Services is a pharmaceutical company.

Athena Therapeutics

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Athena Therapeutics has developed approaches to probe for, identify, and characterize altered states of NAD metabolism and flux.

Metrum Research Group

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Metrum Research Group specializes in quantitative analysis, training, biomedical modeling and drug development programs.

Protein Sciences

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Protein Sciences is a research company that provides the research and creation of new vaccines and other protective medicines.

PRIA Healthcare Management,

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Clinical Trial Reimbursement, Electronic Benefits Verification, Prior Authorizations, Patient-Based Appeals, Strategic Reimbursement

Biological Industries Ltd

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Manufacturer of life science research products in the field of cell culture and molecular biology.

Virscio

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Virscio is a biotechnology company that develops therapeutics for central nervous system disorders such as neurodegeneration, memory

Triumph Research Intelligence

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Triumph Research Intelligence is a risk-Based Monitoring Company.

Galata Chemicals, LLC

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Galata Chemicals, LLC is a chemical firm dealing in specialty chemicals.

Arrien Pharmaceuticals

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Arrien Pharmaceuticals is a small molecule-targeted therapeutics drug discovery and development company targeting cell signaling pathways.

CGI Pharmaceuticals

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CGI Pharmaceuticals, Inc. is a private, development-stage pharmaceutical company.

MinInvasive

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MinInvasive is a medical technology company that focuses on developing rotator cuff repair, the OmniCuff™ System platform.

ChemWerth

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ChemWerth is a full service generic drug development and supply company.

AlloMek Therapeutics LLC

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AlloMek Therapeutics LLC is a privately held pharmaceutical company committed to helping cancer patients

Verinomics

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Verinomics is a consultancy that offers data analysis, genomic and computational services for product development and trait discovery.

Culturelle

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Culturelle is a pharmaceutical company that specializes in probiotics and supplements ensure good digestive health.

Sheffield Pharmaceuticals, LLC

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Sheffield Pharmaceuticals is a pharmaceutical company providing health and beauty care services.

Smpl Bio

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Creating the tools to turn genomic research into medicine

CE3 Inc.

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CE3 is a pharmaceutical company providing gene therapy and cardio-vascular indication solutions.

Neurogen Corp

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Neurogen Corp. is a drug development company historically focusing on small-molecule drugs.

PhytoCeutica

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Phytoceutica, Inc. develops traditional Chinese medicine into FDA-approved prescription drugs for the treatment of cancer. It focuses on

Blue Thunder Technologies

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Distributor of Cleanroom Supplies

Optherion

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Optherion, Inc., a biotechnology company, develops diagnostic and disease-modifying therapeutics for the management and treatment of

Artificial Cell Technologies

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Artificial Cell Technologies is a Biotechnology technology.

IMCORP

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Avista Pharma Solutions a contract development and manufacturing and chemical process design organization

Arvys Proteins Inc.

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Arvys Proteins is a contract research organization offering custom protein services.

Affomix Corporation

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Affomix develops technology for the automated, high-throughput selection of human monoclonal antibodies.

Synowledge

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Synowledge is a global life sciences solutions company providing drug safety, regulatory affairs and relevant IT services.

IsoPlexis

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IsoPlexis is a life science technology company that develops a single-cell detection system identifying patient immune responses.

Purdue Pharma

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Purdue Pharma L.P., a pharmaceutical company committed to improving patients’ lives and serving the healthcare community.

Biohaven Pharmaceutical

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Biohaven is engaged in the identification and development of clinical stage neuroscience compounds targeting the glutamatergic system.

Quantum SI

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Quantum SI offers Next Generation Protein Sequencing that makes diagnostics digital.

Arvinas

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Arvinas focuses on developing novel therapeutics to treat a variety of diseases including cancer, pro-inflammatory, and autoimmune.

Melinta

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Melinta Therapeutics is an antibiotics-focused company that develops and commercializes antibiotics to overcome drug-resistant infections.

SpringWorks Therapeutics

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SpringWorks Therapeutics is a biopharmaceutical company focused on developing medicines for patients with severe rare diseases and cancer.

Marinus Pharmaceuticals

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Marinus, a pharmaceutical company, reformulates, develops and commercializes drugs to treat neurological, psychiatric and pain disorders.

Cara Therapeutics

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Cara Therapeutics is a biotechnology company focused on developing therapeutics to treat diseases associated with pain and inflammation.

Rallybio

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Rallybio is an biotechnological research and development services intended to transform the lives of patients with a devastating disease.

Cybrexa Therapeutics

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A New Haven, CT-based cancer therapeutics company.

Ancera

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Ancera is a biotech company focused on the business of rapid cell separation and pathogen diagnostics.

Azitra

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Azitra is a clinical-stage medical dermatology company that leverages extensive scientific knowledge about the skin microbiome.

BioSig Technologies

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BioSig Technologies offers a platform for the minimization of noise and artifacts from cardiac recordings during electrophysiology studies.

Valisure

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Valisure is a digital pharmacy to chemically validate medications for quality and consistency.

P2 Science

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P2 Science develops a bio-refining process for the conversion of biomass such as vegetable oils into high-value specialty chemicals.

OncoSynergy

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OncoSynergy improves outcomes for patients with unmet needs in oncology with Resistance Mechanism Inhibitors (RMIs).

Oerth Bio

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Oerth Bio is a agriculture-focused biotech firm.

Biorez

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Biorez is a medicine company focused on the development of tendon and ligament healing.

Catalytic Data Science

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Catalytic Data Science is a life science R&D cloud platform that integrates and scales the scientific workflows for researchers.

Seranova Bio

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Seranova Bio develops companion diagnostics or therapeutics to treat autoimmune disease or other autoantibody-driven diseases.

InteRNA Technologies

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InteRNA Technologies provides drug discovery and development services.

Alphina Therapeutics

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Alphina Therapeutics is a biotechnology company that aims to leverage proprietary biomarkers and breakthrough insights for cancer patients.

AtlasXomics

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AtlasXomics is a biotechnology company accelerating spatial multi-omics for application in oncology, neurology, and aging.

Trevi Therapeutics

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Trevi Therapeutics develops drugs for treating uremic pruritus.

Simcha Therapeutics

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Simcha Therapeutics is a biopharmaceutical company developing engineered cytokine immunotherapy for cancer.

ZetrOZ

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ZetrOZ is an innovative ultrasound technology company focused on developing innovative ultrasound products and applications.

GE Healthcare

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GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care.

NanoViricides

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NanoViricides is a nano-biopharmaceutical company that develops therapeutics for patients suffering from life-threatening viral infections.

Kolltan Pharmaceuticals

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Kolltan Pharmaceuticals develops new-generation monoclonal antibody oncology therapeutics.

LambdaVision

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A commercializing a retinal implant to restore vision.

Torigen Pharmaceuticals

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Torigen Pharmaceuticals focuses on providing cancer care solutions for animals.

Intensity Therapeutics

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Intensity Therapeutics is a biopharmaceutical company that provides chemotherapy treatment for cancer patients.

Biowave Corporation

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Smarter neurotechnology medical devices that provide instant, long lasting pain relief.

Lumeda

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Lumeda is a biotechnology company that enables practical intraoperative photodynamic therapy for treating lung cancer.

EvolveImmune Therapeutics

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EvolveImmune Therapeutics transforms the discovery and development of novel immunotherapies.

Brain Tunnelgenix Technologies

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Brain Tunnelgenix Technologies produces non-invasive and continuous temperature measurement devices.

A.D.A.M.

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A.D.A.M. is a biotech company that specializes in on-demand 3D-bioprinting with a primary focus in bone implants.

Thetis Pharmaceuticals

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Thetis Pharmaceuticals is a biopharmaceutical company.

SurgiQuest

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SurgiQuest is a surgical device company in the field of minimally-invasive access technology.

ProteoWise

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ProteoWise offers a technology that provides a unique combination of high information content, high throughput, and low cost.

Precipio Diagnostics

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Precipio Diagnostics is a cancer diagnostics reference laboratory delivering advanced diagnostics, advice and personalized medicine.

ReNetX Bio

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ReNetX Bio is a technology platform help to restore function in patients who are suffering from spinal cord injuries, stroke and glaucoma.

Cytogel Pharma

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Cytogel Pharma is a biopharmaceutical development company that pursues strategic opportunities for pharmaceutical product development.

Biodel

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Biodel is a biopharmaceutical company developing and commercializing therapeutics for the treatment of diabetes.

MD SolarSciences

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MD SolarSciences is a skincare products manufacturing company.

Mederi Therapeutics

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Mederi Therapeutics manufactures medical devices that deliver radio frequency energy to treat diseases affecting the human digestive system.

Ikonisys

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Ikonisys is transforming diagnostic medicine by enabling early, accurate and non-invasive disease detection.

Biorasis

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Biorasis commercializes wireless, needle implantable, miniaturized sensor platforms for real-time glucose monitoring.

CaroGen

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CaroGen develops vaccine candidates targeting hepatitis B and C, and other viral agents.

CyVek

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CyVek engages in the development of a technology platform for measuring analytics in biological samples.

Alexion Pharmaceuticals

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Alexion Pharmaceuticals is a biopharmaceutical company that engages in the development and commercialization of mid-to-late-stage therapies.

Bactana Corp.

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Bactana Develops Novel Probiotics and Postbiotics to Support Sustainable Livestock Farming & Companion Animal Health

Perosphere

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Perosphere is a private specialty pharmaceutical company developing rescue medications.

AxioMx

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AxioMx offers antibody discovery and development services for the research and diagnostics marketplace.

NED Biosystems

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NED Biosystems Developing proprietary combination cancer therapy. Other IP includes diagnostics.

Shoreline Biome

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Shoreline Biome is a developer of microbiome technologies and products created to identify and quantify the bacteria in human microbiome.

Vesselon

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Vesselon is a medical device company developing novel therapeutic Immuno-Oncology complexes.

BioRelix

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BioRelix is engaged in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases.

ImStem Biotechnology

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ImStem Biotechnology is a drug-research platform designed to focus on treatment of heart, vascular and blood system and autoimmune diseases.

Oscillo Biosciences

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Oscillo Biosciences, a biotech company, aims to preserve and restore memory and cognition in people with Alzheimer’s disease and dementias.

Treeline Biosciences

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Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.

Aponia Laboratories

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Aponia Laboratories is a pharmaceutical company producing a series of clinically proven prescription pain relief products.

CMD Bioscience

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CMD Bioscience develops molecular software applications for pharmaceutical, biotech and life sciences companies.

Magellan Health Services

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Magellan Health Services is a healthcare management organization that focuses on managing behavioral healthcare and diagnostic imaging.

BioXcel Therapeutics

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BioXcel Therapeutics is a clinical stage biopharmaceutical company focused on drug development that utilizes novel artificial intelligence.

Affinimark Technologies

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Affinimark Technologies is a bioscience company developing medical diagnostic products for unmet medical needs.

Cogstate Ltd.

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Cogstate is a multi-faceted cognitive assessment and training company

Auxilium Pharmaceuticals

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Auxilium Pharmaceuticals (NASDAQ: AUXL) was founded in 1999 to develop and market pharmaceutical products that focus on urology and sexual

CyOmics

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CyOmics develops and commercializes products that improve workflows and outcomes in Life Sciences and Diagnostics.

Transposon Therapeutics

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Transposon Therapeutics specializes in developing therapeutics for debilitating and life-threatening diseases.

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